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A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion

Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6293), p.1535-1542

2016

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Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.13833-13838

2016

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Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer

Nature communications, 2022-01, Vol.13 (1), p.45-45, Article 45

2022

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Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

Nature communications, 2023-06, Vol.14 (1), p.3652-3652, Article 3652

2023

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An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6539), p.257

2021

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The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

Immunological reviews, 2014-07, Vol.260 (1), p.8-20

2014

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The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice

PloS one, 2015-07, Vol.10 (7), p.e0131991

2015

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Altered Innate Defenses in the Neonatal Gastrointestinal Tract in Response to Colonization by Neuropathogenic Escherichia coli

Infection and Immunity, 2013-09, Vol.81 (9), p.3264-3275

2013

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Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

Cell host & microbe, 2018-01, Vol.23 (1), p.27-40.e7

2018

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Antenatal Ureaplasma Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies

International journal of molecular sciences, 2024-04, Vol.25 (7), p.4000

2024

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Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection

Scientific reports, 2017-03, Vol.7 (1), p.83-83, Article 83

2017

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The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function

The Journal of experimental medicine, 2019-11, Vol.216 (11), p.2602-2618

2019

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NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation

Cell reports (Cambridge), 2021-04, Vol.35 (1), p.108949-108949, Article 108949

2021

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Forming a mucus barrier along the colon

Science (American Association for the Advancement of Science), 2020-10, Vol.370 (6515), p.402-403

2020

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Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice

The Journal of biological chemistry, 2020-11, Vol.295 (46), p.15712-15726

2020

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Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection

Cell reports (Cambridge), 2023-02, Vol.42 (2), p.112084-112084, Article 112084

2023

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Non-invasive model of neuropathogenic Escherichia coli infection in the neonatal rat

Journal of visualized experiments, 2014-10 (92), p.e52018-e52018

2014

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Loss of Trefoil Factor 2 Sensitizes Rat Pups to Systemic Infection with the Neonatal Pathogen Escherichia coli K1

Infection and immunity, 2019-05, Vol.87 (5)

2019

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Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity

EBioMedicine, 2018-07, Vol.33, p.134-143

2018

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New developments in goblet cell mucus secretion and function

Mucosal immunology, 2015-07, Vol.8 (4), p.712-719

2015

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Dietary destabilisation of the balance between the microbiota and the colonic mucus barrier

Gut microbes, 2019-01, Vol.10 (2), p.246-250

2019

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Rainbow trout gastrointestinal mucus, mucin production, mucin glycosylation and response to lipopolysaccharide

Fish & shellfish immunology, 2022-03, Vol.122, p.181-190

2022

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Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons

Scientific reports, 2023-08, Vol.13 (1), p.13701-13701, Article 13701

2023

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Functional mucous layer and healing of proximal colonic anastomoses in an experimental model

British journal of surgery, 2017-04, Vol.104 (5), p.619-630

2017

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Antenatal IUreaplasma/I Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies

International journal of molecular sciences, 2024-04, Vol.25 (7)

2024

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A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer

Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice

Altered Innate Defenses in the Neonatal Gastrointestinal Tract in Response to Colonization by Neuropathogenic Escherichia coli

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

Antenatal Ureaplasma Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies

Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection

The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function

NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation

Forming a mucus barrier along the colon

Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice

Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection

Non-invasive model of neuropathogenic Escherichia coli infection in the neonatal rat

Loss of Trefoil Factor 2 Sensitizes Rat Pups to Systemic Infection with the Neonatal Pathogen Escherichia coli K1

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity

New developments in goblet cell mucus secretion and function

Dietary destabilisation of the balance between the microbiota and the colonic mucus barrier

Rainbow trout gastrointestinal mucus, mucin production, mucin glycosylation and response to lipopolysaccharide

Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons

Functional mucous layer and healing of proximal colonic anastomoses in an experimental model

Antenatal IUreaplasma/I Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies

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