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Cell-based strategies for IVD repair: clinical progress and translational obstacles

Nature reviews. Rheumatology, 2021-03, Vol.17 (3), p.158-175

2021

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Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties

Nature communications, 2020-03, Vol.11 (1), p.1420-1420, Article 1420

2020

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Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration

Arthritis research & therapy, 2014-08, Vol.16 (5), p.416, Article 416

2014

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Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

Scientific reports, 2017-08, Vol.7 (1), p.8935-11, Article 8935

2017

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Nerves are more abundant than blood vessels in the degenerate human intervertebral disc

Arthritis research & therapy, 2015-12, Vol.17 (370), p.370-370, Article 370

2015

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Site-Directed Differentiation of Human Adipose-Derived Mesenchymal Stem Cells to Nucleus Pulposus Cells Using an Injectable Hydroxyl-Functional Diblock Copolymer Worm Gel

Biomacromolecules, 2021-02, Vol.22 (2), p.837-845

2021

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Syndecan-4 in intervertebral disc and cartilage: Saint or synner?

Matrix biology, 2016-05, Vol.52-54, p.355-362

2016

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Combinatorial conditioning of adipose derived‐mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration

JOR-spine, 2019-12, Vol.2 (4), p.e1072-n/a

2019

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Degeneration of the intervertebral disc with new approaches for treating low back pain

Journal of neurosurgical sciences, 2015-03, Vol.59 (1), p.47

2015

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Inhibiting IL‐1 signaling pathways to inhibit catabolic processes in disc degeneration

Journal of orthopaedic research, 2017-01, Vol.35 (1), p.74-85

2017

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Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration

The Journal of biological chemistry, 2013-06, Vol.288 (23), p.16761-16774

2013

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Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction?

Oncotarget, 2016-01, Vol.7 (3), p.2189-2200

2016

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Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc

Oncotarget, 2015-07, Vol.6 (21), p.18338-18354

2015

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Recombinant IL-1Ra Stimulation of Native NP Cells Inhibits a Multitude of Pathological Features

Global Spine Journal, 2014-05, Vol.4 (1_suppl), p.s-0034-1376600-s-0034-1376600

2014

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Human Degenerate Discs Show Increased Activation of Intracellular Signalling Pathways of IL-1

Global Spine Journal, 2014-05, Vol.4 (1_suppl), p.s-0034-1376601-s-0034-1376601

2014

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Role of Semaphorins in Angiogenesis and Innervation in Human Intervertebral Disc Degeneration

Global Spine Journal, 2014-05, Vol.4 (1_suppl), p.s-0034-1376599-s-0034-1376599

2014

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Immunohistochemical analysis of protein expression in formalin fixed paraffin embedded human intervertebral disc tissues

JOR-spine, 2020-09, Vol.3 (3), p.e1098-n/a

2020

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Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells

The Journal of biological chemistry, 2013-06, Vol.288 (23), p.16761-16774

2013

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Harmonization and standardization of nucleus pulposus cell extraction and culture methods

JOR-spine, 2023-03, Vol.6 (1), p.e1238-n/a

2023

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Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells

Oncotarget, 2015-05, Vol.6 (14), p.11945-11958

2015

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Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity

Bioorganic & medicinal chemistry, 2004-01, Vol.12 (2), p.319-326

2004

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SCH 57790, a selective muscarinic M2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals

European journal of pharmacology, 2001-11, Vol.431 (2), p.189-200

2001

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Improving the Oral Efficacy of CNS Drug Candidates: Discovery of Highly Orally Efficacious Piperidinyl Piperidine M2 Muscarinic Receptor Antagonists

Journal of medicinal chemistry, 2002-12, Vol.45 (25), p.5415-5418

2002

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SCH 57790, a selective muscarinic M 2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals

European journal of pharmacology, 2001-11, Vol.431 (2), p.189-200

2001

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Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway

International journal of experimental pathology, 2002-02, Vol.83 (1), p.1-20

2002

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Cell-based strategies for IVD repair: clinical progress and translational obstacles

Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties

Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

Nerves are more abundant than blood vessels in the degenerate human intervertebral disc

Site-Directed Differentiation of Human Adipose-Derived Mesenchymal Stem Cells to Nucleus Pulposus Cells Using an Injectable Hydroxyl-Functional Diblock Copolymer Worm Gel

Syndecan-4 in intervertebral disc and cartilage: Saint or synner?

Combinatorial conditioning of adipose derived‐mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration

Degeneration of the intervertebral disc with new approaches for treating low back pain

Inhibiting IL‐1 signaling pathways to inhibit catabolic processes in disc degeneration

Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration

Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction?

Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc

Recombinant IL-1Ra Stimulation of Native NP Cells Inhibits a Multitude of Pathological Features

Human Degenerate Discs Show Increased Activation of Intracellular Signalling Pathways of IL-1

Role of Semaphorins in Angiogenesis and Innervation in Human Intervertebral Disc Degeneration

Immunohistochemical analysis of protein expression in formalin fixed paraffin embedded human intervertebral disc tissues

Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells

Harmonization and standardization of nucleus pulposus cell extraction and culture methods

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity

SCH 57790, a selective muscarinic M2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals

Improving the Oral Efficacy of CNS Drug Candidates: Discovery of Highly Orally Efficacious Piperidinyl Piperidine M2 Muscarinic Receptor Antagonists

SCH 57790, a selective muscarinic M 2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals

Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway

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