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Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures

Frontiers in pharmacology, 2021-12, Vol.12, p.766082-766082

2021

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Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta

Laboratory investigation, 2021-12, Vol.101 (12), p.1605-1617

2021

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Pre‐synaptic C‐terminal truncated tau is released from cortical synapses in Alzheimer's disease

Journal of neurochemistry, 2015-05, Vol.133 (3), p.368-379

2015

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Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization

Neurobiology of disease, 2015-10, Vol.82, p.552-560

2015

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Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue

International journal of molecular sciences, 2022-05, Vol.23 (9), p.5257

2022

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Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease

Neurobiology of disease, 2018-06, Vol.114, p.120-128

2018

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Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model

Molecular brain, 2021-04, Vol.14 (1), p.70-70, Article 70

2021

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Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model

Molecular brain, 2021-07, Vol.14 (1), p.1-108, Article 108

2021

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Matrix metalloproteinase‐7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation

Journal of neurochemistry, 2006-04, Vol.97 (1), p.44-56

2006

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A Rose by Any Other Name? The Potential Consequences of Microglial Heterogeneity During CNS Health and Disease

Neurotherapeutics, 2007-10, Vol.4 (4), p.571-579

2007

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Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization

Journal of neuroimmunology, 2012-06, Vol.247 (1), p.1-8

2012

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Nanoscale Extracellular Vesicle Analysis in Alzheimer’s Disease Diagnosis and Therapy

International journal of alzheimer's disease, 2016, Vol.2016 (2016), p.1-10

2016

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Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease

Neurobiology of disease, 2015-02, Vol.74, p.32-40

2015

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Enhanced neuronal expression of major histocompatibility complex class I leads to aberrations in neurodevelopment and neurorepair

Journal of neuroimmunology, 2011-03, Vol.232 (1), p.8-16

2011

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Neurons Preferentially Respond to Self-MHC Class I Allele Products Regardless of Peptide Presented

The Journal of immunology (1950), 2010-01, Vol.184 (2), p.816-823

2010

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Brain extracellular vesicles from Alzheimer’s Disease and Down Syndrome patients mediate spread of senescence‐like phenotype in vitro

Alzheimer's & dementia, 2023-12, Vol.19 (S12), p.n/a

2023

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Phenotypic Status Explored in Parietal Cortex of Alzheimer’s Patients and Non‐Demented Controls that Vary on the Spectrum of Neuropathological AD

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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Basic Science and Pathogenesis - Part 2

Alzheimer's & dementia, 2023-12, Vol.19 Suppl 13, p.e073956

2023

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P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Alzheimer's & dementia, 2019-07, Vol.15, p.P1294-P1295

2019

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Pharmacological Rescue of Long-Term Potentiation in Alzheimer Diseased Synapses

The Journal of neuroscience, 2017-02, Vol.37 (5), p.1197-1212

2017

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Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases

The American journal of pathology, 2016, Vol.186 (1), p.185-198

2016

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Evaluation of an Allosteric BACE Inhibitor Peptide to Identify Mimetics that Can Interact with the Loop F Region of the Enzyme and Prevent APP Cleavage

Journal of molecular biology, 2018-05, Vol.430 (11), p.1566-1576

2018

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Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer’s disease cortex

Journal of neuroscience methods, 2024-06, Vol.406, p.110137, Article 110137

2024

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Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4

The American journal of pathology, 2019-08, Vol.189 (8), p.1621-1636

2019

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Analysis of cell‐type specific exosomes isolated from cryopreserved human brain

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures

Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta

Pre‐synaptic C‐terminal truncated tau is released from cortical synapses in Alzheimer's disease

Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization

Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue

Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease

Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model

Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model

Matrix metalloproteinase‐7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation

A Rose by Any Other Name? The Potential Consequences of Microglial Heterogeneity During CNS Health and Disease

Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization

Nanoscale Extracellular Vesicle Analysis in Alzheimer’s Disease Diagnosis and Therapy

Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease

Enhanced neuronal expression of major histocompatibility complex class I leads to aberrations in neurodevelopment and neurorepair

Neurons Preferentially Respond to Self-MHC Class I Allele Products Regardless of Peptide Presented

Brain extracellular vesicles from Alzheimer’s Disease and Down Syndrome patients mediate spread of senescence‐like phenotype in vitro

Phenotypic Status Explored in Parietal Cortex of Alzheimer’s Patients and Non‐Demented Controls that Vary on the Spectrum of Neuropathological AD

Basic Science and Pathogenesis - Part 2

P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Pharmacological Rescue of Long-Term Potentiation in Alzheimer Diseased Synapses

Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases

Evaluation of an Allosteric BACE Inhibitor Peptide to Identify Mimetics that Can Interact with the Loop F Region of the Enzyme and Prevent APP Cleavage

Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer’s disease cortex

Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4

Analysis of cell‐type specific exosomes isolated from cryopreserved human brain

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