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Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists

The Journal of pharmacology and experimental therapeutics, 2015-02, Vol.352 (2), p.281-290

2015

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Nonclinical and clinical pharmacology evidence for cardiovascular safety of saxagliptin

Cardiovascular diabetology, 2017-09, Vol.16 (1), p.113-113, Article 113

2017

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Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections

Journal of biomolecular screening, 2016-02, Vol.21 (2), p.187-193

2016

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Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3

Biochemical pharmacology, 2009-05, Vol.77 (9), p.1522-1530

2009

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A comprehensive analysis of liver safety across zibotentan oncology trials: knowledge of the past offers new perspectives on the present

Expert opinion on drug safety, 2024-04, Vol.23 (4), p.477-486

2024

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Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine

Molecular therapy. Methods & clinical development, 2018-06, Vol.9, p.330-346

2018

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A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin

Regulatory toxicology and pharmacology, 2019-04, Vol.103, p.166-173

2019

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Integrating efficacy and safety: Telemetry and echocardiography in a pig model of myocardial infarction

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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Response to letter from Dr Oliviera in relation to our publication: A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin

Regulatory toxicology and pharmacology, 2019-08, Vol.106, p.347-348

2019

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Rat pre- and postnatal development study with esomeprazole magnesium trihydrate: Lack of F1 bone effects

Reproductive toxicology (Elmsford, N.Y.), 2015-08, Vol.56, p.25-25

2015

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Evaluating the safety pharmacology of a novel modified mRNA therapeutic for patients with ischaemic vascular disease

Journal of pharmacological and toxicological methods, 2018-09, Vol.93, p.151-151

2018

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Dynamic Instability of Microtubules Assembled from Microtubule-Associated Protein-Free Tubulin: Neither Variability of Growth and Shortening Rates nor “Rescue” Requires Microtubule-Associated Proteins

Biochemistry (Easton), 2004-08, Vol.43 (34), p.11144-11144

2004

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Hypersensitivity Events, Including Potentially Hypersensitivity-Related Skin Events, with Dapagliflozin in Patients with Type 2 Diabetes Mellitus: A Pooled Analysis

Clinical drug investigation, 2016-11, Vol.36 (11), p.925-933

2016

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Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats

Toxicologic pathology, 2018-02, Vol.46 (2), p.147-157

2018

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Dynamic Instability of Microtubules Assembled from Microtubule-Associated Protein-Free Tubulin: Neither Variability of Growth and Shortening Rates nor “Rescue” Requires Microtubule-Associated Proteins

Biochemistry (Easton), 1996-10, Vol.35 (42), p.13656-13663

1996

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Regulation and stability of microtubules from the Atlantic cod, Gadus morhua

Billger, Martin Anders

1993

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Preclinical Toxicology Evaluation

Early Drug Development, 2018, p.499-526

2018

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Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules

Cell calcium (Edinburgh), 1988, Vol.9 (1), p.33-44

1988

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Microtubule-Associated Proteins-Dependent Colchicine Stability of Acetylated Cold-Labile Brain Microtubules from the Atlantic Cod, Gadus morhua

The Journal of cell biology, 1991-04, Vol.113 (2), p.331-338

1991

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Distribution of acetylated tubulin in cultured cells and tissues from the Atlantic cod ( Gadus morhua). Role of acetylation in cold adaptation and drug stability

Cell biology international, 1995-09, Vol.19 (9), p.749-758

1995

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Microtubule-associated protein 2 appears in axons of cultured dorsal root ganglia and spinal cord neurons after rotavirus infection

Journal of neuroscience research, 1993-10, Vol.36 (2), p.173-182

1993

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Assembly of Atlantic Cod ( Gadus morhua) Brain Microtubules at Different Temperatures: Dependency of Microtubule-Associated Proteins Is Relative to Temperature

Archives of biochemistry and biophysics, 1993-11, Vol.307 (1), p.200-205

1993

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Calpain processing of brain microtubules from the Atlantic Cod, Gadus morhua

Molecular and cellular biochemistry, 1993-04, Vol.121 (1), p.85-92

1993

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Coassembly of bovine and cod microtubule proteins: The ratio of the different tubulins within hybrid microtubules determines the ability to assemble at low temperatures, MAPs dependency and effects of Ca2

Cell motility and the cytoskeleton, 1997, Vol.38 (3), p.297-307

1997

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Studies of the interaction of chemicals with microtubule assembly in vitro can be used as an assay for detection of cytotoxic chemicals and possible inducers of aneuploidy

Mutation research, 1988-10, Vol.201 (2), p.303-311

1988

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Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists

Nonclinical and clinical pharmacology evidence for cardiovascular safety of saxagliptin

Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections

Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3

A comprehensive analysis of liver safety across zibotentan oncology trials: knowledge of the past offers new perspectives on the present

Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine

A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin

Integrating efficacy and safety: Telemetry and echocardiography in a pig model of myocardial infarction

Response to letter from Dr Oliviera in relation to our publication: A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin

Rat pre- and postnatal development study with esomeprazole magnesium trihydrate: Lack of F1 bone effects

Evaluating the safety pharmacology of a novel modified mRNA therapeutic for patients with ischaemic vascular disease

Dynamic Instability of Microtubules Assembled from Microtubule-Associated Protein-Free Tubulin: Neither Variability of Growth and Shortening Rates nor “Rescue” Requires Microtubule-Associated Proteins

Hypersensitivity Events, Including Potentially Hypersensitivity-Related Skin Events, with Dapagliflozin in Patients with Type 2 Diabetes Mellitus: A Pooled Analysis

Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats

Dynamic Instability of Microtubules Assembled from Microtubule-Associated Protein-Free Tubulin: Neither Variability of Growth and Shortening Rates nor “Rescue” Requires Microtubule-Associated Proteins

Regulation and stability of microtubules from the Atlantic cod, Gadus morhua

Preclinical Toxicology Evaluation

Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules

Microtubule-Associated Proteins-Dependent Colchicine Stability of Acetylated Cold-Labile Brain Microtubules from the Atlantic Cod, Gadus morhua

Distribution of acetylated tubulin in cultured cells and tissues from the Atlantic cod ( Gadus morhua). Role of acetylation in cold adaptation and drug stability

Microtubule-associated protein 2 appears in axons of cultured dorsal root ganglia and spinal cord neurons after rotavirus infection

Assembly of Atlantic Cod ( Gadus morhua) Brain Microtubules at Different Temperatures: Dependency of Microtubule-Associated Proteins Is Relative to Temperature

Calpain processing of brain microtubules from the Atlantic Cod, Gadus morhua

Coassembly of bovine and cod microtubule proteins: The ratio of the different tubulins within hybrid microtubules determines the ability to assemble at low temperatures, MAPs dependency and effects of Ca2

Studies of the interaction of chemicals with microtubule assembly in vitro can be used as an assay for detection of cytotoxic chemicals and possible inducers of aneuploidy

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