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Polyoxometalates as Potential Next‐Generation Metallodrugs in the Combat Against Cancer

Angewandte Chemie International Edition, 2019-03, Vol.58 (10), p.2980-2999

International ed. in English, 2019

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The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectives

Chemical communications (Cambridge, England), 2018, Vol.54 (10), p.1153-1169

2018

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Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity

Scientific reports, 2019-03, Vol.9 (1), p.4022-4022, Article 4022

2019

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Heterologous expression and characterization of functional mushroom tyrosinase (AbPPO4)

Scientific reports, 2017-05, Vol.7 (1), p.1810-10, Article 1810

2017

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A Peptide‐Induced Self‐Cleavage Reaction Initiates the Activation of Tyrosinase

Angewandte Chemie International Edition, 2019-05, Vol.58 (22), p.7475-7479

International ed. in English, 2019

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The Structure of a Plant Tyrosinase from Walnut Leaves Reveals the Importance of "Substrate-Guiding Residues" for Enzymatic Specificity

Angewandte Chemie (International ed.), 2015-12, Vol.54 (49), p.14677-14680

International ed. in English, 2015

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Three recombinantly expressed apple tyrosinases suggest the amino acids responsible for mono- versus diphenolase activity in plant polyphenol oxidases

Scientific reports, 2017-08, Vol.7 (1), p.8860-13, Article 8860

2017

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Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer

Scientific reports, 2024-08, Vol.14 (1), p.18093-12, Article 18093

2024

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Conversion of walnut tyrosinase into a catechol oxidase by site directed mutagenesis

Scientific reports, 2020-02, Vol.10 (1), p.1659, Article 1659

2020

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The use of polyoxometalates in protein crystallography – An attempt to widen a well-known bottleneck

Coordination chemistry reviews, 2015-09, Vol.299, p.22-38

2015

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Ten Good Reasons for the Use of the Tellurium-Centered Anderson–Evans Polyoxotungstate in Protein Crystallography

Accounts of chemical research, 2017-06, Vol.50 (6), p.1441-1448

2017

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The potential of hexatungstotellurate(VI) to induce a significant entropic gain during protein crystallization

IUCrJ, 2017-11, Vol.4 (Pt 6), p.734-740

2017

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Flavofun: Exploration of fungal flavoproteomes

Frontiers in catalysis, 2022-12, Vol.2

2022

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In situ formation of the first proteinogenically functionalized [TeW 6 O 24 O 2 (Glu)] 7- structure reveals unprecedented chemical and geometrical features of the Anderson-type cluster

Chemical communications (Cambridge, England), 2016-10, Vol.52 (83), p.12286-12289

2016

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The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms

PloS one, 2018-06, Vol.13 (6), p.e0199639-e0199639

2018

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Polyoxometalates: more than a phasing tool in protein crystallography

ChemTexts (Cham), 2018-01, Vol.4 (3), p.10-27, Article 10

2018

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Transition metal-substituted Keggin polyoxotungstates enabling covalent attachment to proteinase K upon co-crystallization

Chemical communications (Cambridge, England), 2019-09, Vol.55 (77), p.11519-11522

2019

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X‑ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H‑indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5894-5903

2016

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Binding of a Fatty Acid-Functionalized Anderson-Type Polyoxometalate to Human Serum Albumin

Inorganic chemistry, 2020-04, Vol.59 (8), p.5243-5246

2020

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Loop 6 and the β‐hairpin flap are structural hotspots that determine cofactor specificity in the FMN‐dependent family of ene‐reductases

The FEBS journal, 2024-04, Vol.291 (7), p.1560-1574

2024

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The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectivesElectronic supplementary information (ESI) available: Additional MIC tables, additional compound figures and additional structure-relationship graphs. See DOI: 10.1039/c7cc07549a

2018-01

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The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectives† †Electronic supplementary information (ESI) available: Additional MIC tables, additional compound figures and additional structure-relationship graphs. See DOI: 10.1039/c7cc07549a

Chemical communications (Cambridge, England), 2018-01, Vol.54 (10), p.1153-1169

2018

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Eine peptidvermittelte Selbstspaltungsreaktion initiiert die Tyrosinaseaktivierung

Angewandte Chemie, 2019-05, Vol.131 (22), p.7553-7557

2019

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In situ formation of the first proteinogenically functionalized [TeW6O24O2(Glu)]7− structure reveals unprecedented chemical and geometrical features of the Anderson-type clusterElectronic supplementary information (ESI) available: Full experimental details and additional figures are provided. See DOI: 10.1039/c6cc07004c

2016-10

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In situ formation of the first proteinogenically functionalized [TeW6O24O2(Glu)]7– structure reveals unprecedented chemical and geometrical features of the Anderson-type cluster† †Electronic supplementary information (ESI) available: Full experimental details and additional figures are provided. See DOI: 10.1039/c6cc07004c Click here for additional data file. Click here for additional data file. Click here for additional data file

Chemical communications (Cambridge, England), 2016-09, Vol.52 (83), p.12286-12289

2016

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Polyoxometalates as Potential Next‐Generation Metallodrugs in the Combat Against Cancer

The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectives

Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity

Heterologous expression and characterization of functional mushroom tyrosinase (AbPPO4)

A Peptide‐Induced Self‐Cleavage Reaction Initiates the Activation of Tyrosinase

The Structure of a Plant Tyrosinase from Walnut Leaves Reveals the Importance of "Substrate-Guiding Residues" for Enzymatic Specificity

Three recombinantly expressed apple tyrosinases suggest the amino acids responsible for mono- versus diphenolase activity in plant polyphenol oxidases

Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer

Conversion of walnut tyrosinase into a catechol oxidase by site directed mutagenesis

The use of polyoxometalates in protein crystallography – An attempt to widen a well-known bottleneck

Ten Good Reasons for the Use of the Tellurium-Centered Anderson–Evans Polyoxotungstate in Protein Crystallography

The potential of hexatungstotellurate(VI) to induce a significant entropic gain during protein crystallization

Flavofun: Exploration of fungal flavoproteomes

In situ formation of the first proteinogenically functionalized [TeW 6 O 24 O 2 (Glu)] 7- structure reveals unprecedented chemical and geometrical features of the Anderson-type cluster

The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms

Polyoxometalates: more than a phasing tool in protein crystallography

Transition metal-substituted Keggin polyoxotungstates enabling covalent attachment to proteinase K upon co-crystallization

X‑ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H‑indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

Binding of a Fatty Acid-Functionalized Anderson-Type Polyoxometalate to Human Serum Albumin

Loop 6 and the β‐hairpin flap are structural hotspots that determine cofactor specificity in the FMN‐dependent family of ene‐reductases

The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectivesElectronic supplementary information (ESI) available: Additional MIC tables, additional compound figures and additional structure-relationship graphs. See DOI: 10.1039/c7cc07549a

The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectives† †Electronic supplementary information (ESI) available: Additional MIC tables, additional compound figures and additional structure-relationship graphs. See DOI: 10.1039/c7cc07549a

Eine peptidvermittelte Selbstspaltungsreaktion initiiert die Tyrosinaseaktivierung

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