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Animal Transcription Networks as Highly Connected, Quantitative Continua

Developmental cell, 2011-10, Vol.21 (4), p.611-626

Biggin, Mark D.

2011

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Statistics requantitates the central dogma

Science (American Association for the Advancement of Science), 2015-03, Vol.347 (6226), p.1066-1067

2015

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System wide analyses have underestimated protein abundances and the importance of transcription in mammals

PeerJ (San Francisco, CA), 2014-02, Vol.2, p.e270-e270

2014

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The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding

Genome biology, 2011-04, Vol.12 (4), p.R34-R34, Article R34

2011

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Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development

PLoS genetics, 2011-02, Vol.7 (2), p.e1001290-e1001290

2011

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Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species

PLoS biology, 2010-03, Vol.8 (3), p.e1000343-e1000343

2010

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Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

Genome biology, 2009-01, Vol.10 (7), p.R80-R80, Article R80

2009

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DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21330-21335

2012

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Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm

PLoS biology, 2008-02, Vol.6 (2), p.e27-e27

2008

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NELF and GAGA Factor Are Linked to Promoter-Proximal Pausing at Many Genes in Drosophila

Molecular and Cellular Biology, 2008-05, Vol.28 (10), p.3290-3300

2008

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A Quantitative Spatiotemporal Atlas of Gene Expression in the Drosophila Blastoderm

Cell, 2008-04, Vol.133 (2), p.364-374

2008

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Large-scale turnover of functional transcription factor binding sites in Drosophila

PLoS computational biology, 2006-10, Vol.2 (10), p.e130-e130

2006

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A conserved developmental patterning network produces quantitatively different output in multiple species of Drosophila

PLoS genetics, 2011-10, Vol.7 (10), p.e1002346-e1002346

2011

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Quantitating translational control: mRNA abundance-dependent and independent contributions and the mRNA sequences that specify them

Nucleic acids research, 2017-11, Vol.45 (20), p.11821-11836

2017

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Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution II: dynamics

Genome biology, 2006-01, Vol.7 (12), p.R124-R124

2006

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Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline

Genome biology, 2006-01, Vol.7 (12), p.R123-R123

2006

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Dynamic reprogramming of chromatin accessibility during Drosophila embryo development

Genome biology, 2011-05, Vol.12 (5), p.R43-R43

2011

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Survey of large protein complexes in D. vulgaris reveals great structural diversity

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (39), p.16580-16585

2009

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Nonparametric identification of regulatory interactions from spatial and temporal gene expression data

BMC bioinformatics, 2010-08, Vol.11 (1), p.413-413, Article 413

2010

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Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (3), p.900-908

2019

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MyoD, a Lesson in Widespread DNA Binding

Developmental cell, 2010-04, Vol.18 (4), p.505-506

Biggin, Mark D.

2010

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Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome

Chromosoma, 2008-02, Vol.117 (1), p.89-102

2008

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Zeste maintains repression of Ubx transgenes: support for a new model of Polycomb repression

Development (Cambridge), 2002-03, Vol.129 (6), p.1339-1343

2002

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Quantitative Tagless Copurification: A Method to Validate and Identify Protein-Protein Interactions

Molecular & cellular proteomics, 2016-06, Vol.15 (6), p.2186-2202

2016

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Bacterial Interactomes: Interacting Protein Partners Share Similar Function and Are Validated in Independent Assays More Frequently Than Previously Reported

Molecular & cellular proteomics, 2016-05, Vol.15 (5), p.1539-1555

2016

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Animal Transcription Networks as Highly Connected, Quantitative Continua

Statistics requantitates the central dogma

System wide analyses have underestimated protein abundances and the importance of transcription in mammals

The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding

Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development

Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species

Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila

Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm

NELF and GAGA Factor Are Linked to Promoter-Proximal Pausing at Many Genes in Drosophila

A Quantitative Spatiotemporal Atlas of Gene Expression in the Drosophila Blastoderm

Large-scale turnover of functional transcription factor binding sites in Drosophila

A conserved developmental patterning network produces quantitatively different output in multiple species of Drosophila

Quantitating translational control: mRNA abundance-dependent and independent contributions and the mRNA sequences that specify them

Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution II: dynamics

Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline

Dynamic reprogramming of chromatin accessibility during Drosophila embryo development

Survey of large protein complexes in D. vulgaris reveals great structural diversity

Nonparametric identification of regulatory interactions from spatial and temporal gene expression data

Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy

MyoD, a Lesson in Widespread DNA Binding

Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome

Zeste maintains repression of Ubx transgenes: support for a new model of Polycomb repression

Quantitative Tagless Copurification: A Method to Validate and Identify Protein-Protein Interactions

Bacterial Interactomes: Interacting Protein Partners Share Similar Function and Are Validated in Independent Assays More Frequently Than Previously Reported

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