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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

Diabetologia, 2007-04, Vol.50 (4), p.752-763

2007

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Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload

Diabetologia, 2009-11, Vol.52 (11), p.2369-2373

2009

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G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

Diabetologia, 2012-10, Vol.55 (10), p.2682-2692

2012

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Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

Diabetologia, 2011-07, Vol.54 (7), p.1766-1776

2011

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Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

Diabetologia, 2012-11, Vol.55 (11), p.2999-3009

2012

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Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice

Diabetologia, 2011-06, Vol.54 (6), p.1447-1456

2011

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Cross-talk between the unfolded protein response and nuclear factor-[kappa]B signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

Diabetologia, 2012-11, Vol.55 (11), p.2999

2012

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Diverse roles for protein kinase C δ and protein kinase C ε in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C δ

Diabetologia, 2009-12, Vol.52 (12), p.2616-2620

2009

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Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells

British journal of cancer, 2013-12, Vol.109 (12), p.3034-3041

2013

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Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo

Diabetologia, 2011-02, Vol.54 (2), p.380-389

2011

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Ceramide Generation Is Sufficient to Account for the Inhibition of the Insulin-stimulated PKB Pathway in C2C12 Skeletal Muscle Cells Pretreated with Palmitate

The Journal of biological chemistry, 1999-08, Vol.274 (34), p.24202-24210

1999

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Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle

Diabetologia, 2007-08, Vol.50 (8), p.1732-1742

2007

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Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

Diabetes (New York, N.Y.), 1997-02, Vol.46 (2), p.169-178

1997

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Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

Diabetes (New York, N.Y.), 1997-02, Vol.46 (2), p.169-178

1997

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G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

Diabetologia, 2012-10, Vol.55 (10), p.2682-2692

2012

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Protein Kinase Cδ Activation by Interleukin-1β Stabilizes Inducible Nitric-oxide Synthase mRNA in Pancreatic β-Cells

The Journal of biological chemistry, 2001-02, Vol.276 (7), p.5368-5374

2001

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Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice

The EMBO journal, 2004-02, Vol.23 (3), p.582-593

2004

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Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets

Diabetes (New York, N.Y.), 2000-03, Vol.49 (3), p.392-398

2000

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Inhibition of PKCα induces a PKCδ-dependent apoptotic program in salivary epithelial cells

Cell death and differentiation, 2003-03, Vol.10 (3), p.269-277

2003

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Structural subtypes of the dopamine D2 receptor are functionally distinct : expression of the cloned D2A and D2B subtypes in a heterologous cell line

Molecular endocrinology (Baltimore, Md.), 1992-06, Vol.6 (6), p.920-926

1992

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Protein Kinase Cι Activity Is Necessary for Bcr-Abl-mediated Resistance to Drug-induced Apoptosis

The Journal of biological chemistry, 1999-02, Vol.274 (7), p.3927-3930

1999

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Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat

American journal of physiology: endocrinology and metabolism, 1999-12, Vol.277 (6), p.E1070-E1076

1999

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Inhibition of glycogen synthesis by fatty acid in C2C12 muscle cells is independent of PKC-alpha , -epsilon , and -theta

American journal of physiology: endocrinology and metabolism, 2002-06, Vol.282 (6), p.E1204

2002

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Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells

Diabetes (New York, N.Y.), 1999-12, Vol.48 (12), p.2383-2389

1999

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Acute reversal of lipid-induced muscle insulin resistance is associated with rapid alteration in PKC-theta localization

American journal of physiology: endocrinology and metabolism, 2000-11, Vol.279 (5), p.E1196-E1201

2000

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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice

Cross-talk between the unfolded protein response and nuclear factor-[kappa]B signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

Diverse roles for protein kinase C δ and protein kinase C ε in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C δ

Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells

Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo

Ceramide Generation Is Sufficient to Account for the Inhibition of the Insulin-stimulated PKB Pathway in C2C12 Skeletal Muscle Cells Pretreated with Palmitate

Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle

Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

Protein Kinase Cδ Activation by Interleukin-1β Stabilizes Inducible Nitric-oxide Synthase mRNA in Pancreatic β-Cells

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice

Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets

Inhibition of PKCα induces a PKCδ-dependent apoptotic program in salivary epithelial cells

Structural subtypes of the dopamine D2 receptor are functionally distinct : expression of the cloned D2A and D2B subtypes in a heterologous cell line

Protein Kinase Cι Activity Is Necessary for Bcr-Abl-mediated Resistance to Drug-induced Apoptosis

Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat

Inhibition of glycogen synthesis by fatty acid in C2C12 muscle cells is independent of PKC-alpha , -epsilon , and -theta

Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells

Acute reversal of lipid-induced muscle insulin resistance is associated with rapid alteration in PKC-theta localization

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