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Why are antiepileptic drugs used for nonepileptic conditions?

Epilepsia (Copenhagen), 2012-12, Vol.53 (s7), p.26-33

Bialer, Meir

2012

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How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?

Epilepsia (Copenhagen), 2012-12, Vol.53 (s8), p.3-11

Bialer, Meir

2012

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Key factors in the discovery and development of new antiepileptic drugs

Nature reviews. Drug discovery, 2010-01, Vol.9 (1), p.68-82

2010

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Development of new antiepileptic drugs: challenges, incentives, and recent advances

Lancet neurology, 2007-09, Vol.6 (9), p.793-804

2007

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Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development

Epilepsia (Copenhagen), 2018-10, Vol.59 (10), p.1811-1841

2018

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Stereoselective Analysis of the Antiseizure Activity of Fenfluramine and Norfenfluramine in Mice: Is l -Norfenfluramine a Better Follow-Up Compound to Racemic-Fenfluramine?

International journal of molecular sciences, 2024-02, Vol.25 (5), p.2522

2024

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Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)

Epilepsy research, 2013-01, Vol.103 (1), p.2-30

2013

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Chemical properties of antiepileptic drugs (AEDs)

Advanced drug delivery reviews, 2012-07, Vol.64 (10), p.887-895

Bialer, Meir

2012

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Critical Aspects Affecting Cannabidiol Oral Bioavailability and Metabolic Elimination, and Related Clinical Implications

CNS drugs, 2020-08, Vol.34 (8), p.795-800

2020

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Does cannabidiol have antiseizure activity independent of its interactions with clobazam? An appraisal of the evidence from randomized controlled trials

Epilepsia (Copenhagen), 2020-06, Vol.61 (6), p.1082-1089

2020

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Synthesis and Enantioselective Pharmacokinetic/Pharmacodynamic Analysis of New CNS-Active Sulfamoylphenyl Carbamate Derivatives

International journal of molecular sciences, 2021-03, Vol.22 (7), p.3361

2021

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Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.1078-1082

2019

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Lorcaserin for Dravet Syndrome: A Potential Advance Over Fenfluramine?

CNS drugs, 2022-02, Vol.36 (2), p.113-122

2022

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Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase

International journal of molecular sciences, 2017-09, Vol.18 (9), p.1912

2017

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Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice

Bipolar disorders, 2015-09, Vol.17 (6), p.615-625

2015

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Cannabidiol in the treatment of epilepsy: Current evidence and perspectives for further research

Neuropharmacology, 2021-03, Vol.185, p.108442, Article 108442

2021

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Response: Cannabidiol antiseizure activity and its interactions with clobazam: “It’s déjà vu all over again” Yogi Berra

Epilepsia (Copenhagen), 2020-08, Vol.61 (8), p.1793-1794

2020

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Pharmacokinetic and pharmacodynamic analysis of (2S,3S)‐sec‐butylpropylacetamide (SPD) in rats and pigs—A CNS‐active stereoisomer of SPD

Epilepsia (Copenhagen), 2020-01, Vol.61 (1), p.149-156

2020

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Therapeutic drug monitoring of the newer antiepileptic drugs

Therapeutic drug monitoring, 2003-06, Vol.25 (3), p.347-363

2003

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Generic Products of Antiepileptic Drugs (AEDs): Is It an Issue?

Epilepsia (Copenhagen), 2007-10, Vol.48 (10), p.1825-1832

Bialer, Meir

2007

Volltextzugriff (PDF)

The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

Disease models & mechanisms, 2012-01, Vol.5 (1), p.115-124

2012

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Effects of CYP4F2 Polymorphism on Response to Warfarin During Induction Phase: A Prospective, Open-Label, Observational Cohort Study

Clinical therapeutics, 2012-04, Vol.34 (4), p.811-823

2012

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The Interplay Between Liver First-Pass Effect and Lymphatic Absorption of Cannabidiol and Its Implications for Cannabidiol Oral Formulations

Clinical pharmacokinetics, 2020-12, Vol.59 (12), p.1493-1500

2020

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Effect of Topiramate or Carbamazepine on the Pharmacokinetics of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol in Healthy Obese and Nonobese Female Subjects

Epilepsia (Copenhagen), 2003-04, Vol.44 (4), p.540-549

2003

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New GABATargeting Therapies for the Treatment of Seizures and Epilepsy: I. Role of GABA as a Modulator of Seizure Activity and Recently Approved Medications Acting on the GABA System

CNS drugs, 2023-09, Vol.37 (9), p.755-779

2023

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Why are antiepileptic drugs used for nonepileptic conditions?

How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?

Key factors in the discovery and development of new antiepileptic drugs

Development of new antiepileptic drugs: challenges, incentives, and recent advances

Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development

Stereoselective Analysis of the Antiseizure Activity of Fenfluramine and Norfenfluramine in Mice: Is l -Norfenfluramine a Better Follow-Up Compound to Racemic-Fenfluramine?

Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)

Chemical properties of antiepileptic drugs (AEDs)

Critical Aspects Affecting Cannabidiol Oral Bioavailability and Metabolic Elimination, and Related Clinical Implications

Does cannabidiol have antiseizure activity independent of its interactions with clobazam? An appraisal of the evidence from randomized controlled trials

Synthesis and Enantioselective Pharmacokinetic/Pharmacodynamic Analysis of New CNS-Active Sulfamoylphenyl Carbamate Derivatives

Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative

Lorcaserin for Dravet Syndrome: A Potential Advance Over Fenfluramine?

Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase

Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice

Cannabidiol in the treatment of epilepsy: Current evidence and perspectives for further research

Response: Cannabidiol antiseizure activity and its interactions with clobazam: “It’s déjà vu all over again” Yogi Berra

Pharmacokinetic and pharmacodynamic analysis of (2S,3S)‐sec‐butylpropylacetamide (SPD) in rats and pigs—A CNS‐active stereoisomer of SPD

Therapeutic drug monitoring of the newer antiepileptic drugs

Generic Products of Antiepileptic Drugs (AEDs): Is It an Issue?

The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

Effects of CYP4F2 Polymorphism on Response to Warfarin During Induction Phase: A Prospective, Open-Label, Observational Cohort Study

The Interplay Between Liver First-Pass Effect and Lymphatic Absorption of Cannabidiol and Its Implications for Cannabidiol Oral Formulations

Effect of Topiramate or Carbamazepine on the Pharmacokinetics of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol in Healthy Obese and Nonobese Female Subjects

New GABATargeting Therapies for the Treatment of Seizures and Epilepsy: I. Role of GABA as a Modulator of Seizure Activity and Recently Approved Medications Acting on the GABA System

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