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Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification

Nature communications, 2021-02, Vol.12 (1), p.731-14, Article 731

2021

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Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (52), p.18625-18630

2014

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Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

PloS one, 2015-09, Vol.10 (9), p.e0138780-e0138780

2015

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Optimizing high-throughput viral vector characterization with density gradient equilibrium analytical ultracentrifugation

European biophysics journal, 2023-07, Vol.52 (4-5), p.387-392

2023

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Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (47), p.18966-18971

2011

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A Spiking Neural Network Model of the Lateral Geniculate Nucleus on the SpiNNaker Machine

Frontiers in neuroscience, 2017-08, Vol.11, p.454-454

2017

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Allostery in Hsp70 Chaperones Is Transduced by Subdomain Rotations

Journal of molecular biology, 2009-05, Vol.388 (3), p.475-490

2009

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Molecular dynamics investigation of DNA fragments bound to the anti-HIV protein SAMHD1 reveals alterations in allosteric communications

Journal of molecular graphics & modelling, 2024-06, Vol.129, p.108748-108748, Article 108748

2024

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Molecular dynamics simulations shows real-time lid opening in Hsp70 chaperone

Journal of molecular graphics & modelling, 2024-06, Vol.129, p.108726-108726, Article 108726

2024

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Molecular dynamics investigation of a redox switch in the anti‐HIV protein SAMHD1

Proteins, structure, function, and bioinformatics, 2019-09, Vol.87 (9), p.748-759

2019

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Dimeric Hold States of Anti-HIV Protein SAMHD1 are Redox Tunable

Journal of chemical information and modeling, 2020-12, Vol.60 (12), p.6377-6391

2020

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Molecular dynamics simulations suggest novel allosteric modes in the Hsp70 chaperone protein

Journal of biomolecular structure & dynamics, 2023-12, p.1-19

2023

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A comparison of data quality using quartz vs. sapphire cell windows in analytical ultracentrifugation

European biophysics journal, 2020-12, Vol.49 (8), p.719-727

2020

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Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations

Proteins, structure, function, and bioinformatics, 2017-07, Vol.85 (7), p.1266-1275

2017

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MicroRNA Regulation of Oxidative Stress

Oxidative medicine and cellular longevity, 2017-01, Vol.2017 (1), p.2872156-2872156

2017

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Allosteric Signal Transduction in HIV‑1 Restriction Factor SAMHD1 Proceeds via Reciprocal Handshake across Monomers

Journal of chemical information and modeling, 2017-10, Vol.57 (10), p.2523-2538

2017

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Cover Image, Volume 85, Issue 7

Proteins, structure, function, and bioinformatics, 2017-07, Vol.85 (7)

2017

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Purity and DNA content of AAV capsids assessed by analytical ultracentrifugation and orthogonal biophysical techniques

European journal of pharmaceutics and biopharmaceutics, 2023-08, Vol.189, p.68-83

2023

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Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations

Proteins, structure, function, and bioinformatics, 2017-10, Vol.85 (10), p.1962-1962

2017

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Toward Understanding How Cleavage & Polyadenylation Factor 6 Interacts with the HIV-1 Capsid Hexamer

Biophysical journal, 2014-01, Vol.106 (2), p.61a-61a

2014

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Allosteric Activation of SAMHD1 Protein by Deoxynucleotide Triphosphate (dNTP)-dependent Tetramerization Requires dNTP Concentrations That Are Similar to dNTP Concentrations Observed in Cycling T Cells

The Journal of biological chemistry, 2016-10, Vol.291 (41), p.21407-21413

2016

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Forging a far-right friendship: How Israel became a model for Modi's India

Green left weekly, 2024-05 (1406), p.1-4d

Akash Bhattacharya

2024

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Rhesus Monkey TRIM5α SPRY Domain Recognizes Multiple Epitopes That Span Several Capsid Monomers on the Surface of the HIV-1 Mature Viral Core

Journal of molecular biology, 2013-12, Vol.425 (24), p.5032-5044

2013

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Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect

Scientific reports, 2016-08, Vol.6 (1), p.31353-31353, Article 31353

2016

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Virtual Screening and Molecular Docking of Flavone Derivatives as a Potential Anticancer Drug in the Presence of Dexamethasone

Biointerface Research in Applied Chemistry, 2023-06, Vol.13 (3), p.215

2023

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Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

Optimizing high-throughput viral vector characterization with density gradient equilibrium analytical ultracentrifugation

Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface

A Spiking Neural Network Model of the Lateral Geniculate Nucleus on the SpiNNaker Machine

Allostery in Hsp70 Chaperones Is Transduced by Subdomain Rotations

Molecular dynamics investigation of DNA fragments bound to the anti-HIV protein SAMHD1 reveals alterations in allosteric communications

Molecular dynamics simulations shows real-time lid opening in Hsp70 chaperone

Molecular dynamics investigation of a redox switch in the anti‐HIV protein SAMHD1

Dimeric Hold States of Anti-HIV Protein SAMHD1 are Redox Tunable

Molecular dynamics simulations suggest novel allosteric modes in the Hsp70 chaperone protein

A comparison of data quality using quartz vs. sapphire cell windows in analytical ultracentrifugation

Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations

MicroRNA Regulation of Oxidative Stress

Allosteric Signal Transduction in HIV‑1 Restriction Factor SAMHD1 Proceeds via Reciprocal Handshake across Monomers

Cover Image, Volume 85, Issue 7

Purity and DNA content of AAV capsids assessed by analytical ultracentrifugation and orthogonal biophysical techniques

Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations

Toward Understanding How Cleavage & Polyadenylation Factor 6 Interacts with the HIV-1 Capsid Hexamer

Allosteric Activation of SAMHD1 Protein by Deoxynucleotide Triphosphate (dNTP)-dependent Tetramerization Requires dNTP Concentrations That Are Similar to dNTP Concentrations Observed in Cycling T Cells

Forging a far-right friendship: How Israel became a model for Modi's India

Rhesus Monkey TRIM5α SPRY Domain Recognizes Multiple Epitopes That Span Several Capsid Monomers on the Surface of the HIV-1 Mature Viral Core

Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect

Virtual Screening and Molecular Docking of Flavone Derivatives as a Potential Anticancer Drug in the Presence of Dexamethasone

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