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Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.131-141

2019

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Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.216-223

2017

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The Promises of Quantitative Proteomics in Precision Medicine

Journal of pharmaceutical sciences, 2017-03, Vol.106 (3), p.738-744

2017

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Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.943-952

2018

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Interindividual variability in hepatic expression of human sulfotransferase 2A1: Absolute quantification by LC-MS/MS proteomics and effect of ethnicity, genotype, age and gender

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S16-S16

2019

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Critical Issues and Optimized Practices in Quantification of Protein Abundance Level to Determine Interindividual Variability in DMET Proteins by LC‐MS/MS Proteomics

Clinical pharmacology and therapeutics, 2018-04, Vol.103 (4), p.619-630

2018

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Effect of oral testosterone on the plasma steroid metabolomics in humans

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S58-S58

2018

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Quantitative Proteomics Reveals Changes in Transporter Protein Abundance in Liver, Kidney and Brain of Mice by Pregnancy

Drug metabolism letters, 2018, Vol.12 (2), p.145-152

2018

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Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats

FEBS letters, 2007-05, Vol.581 (10), p.2027-2035

2007

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ADME QPrOmicstm mrm database: A repository of validated LC-MS/MS methods for ADME protein quantification

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S42-S42

2017

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Critical issues and optimized practices in quantification of protein abundance level to determine inter-individual variability in DMET proteins by LC-MS/MS proteomics

Clinical pharmacology and therapeutics, 2017-09, Vol.103 (4), p.619-630

2017

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Best Practices for Robust LC‐MS/MS Quantification of Drug Metabolizing Enzymes and Transporters to Predict Inter‐Individual Variability: Case Examples of Hepatic Cytosolic ADHs and ALDH1A1

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice

Drug metabolism and disposition, 2018-08, Vol.46 (8), p.1226-1240

2018

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In Vivo-to-In Vitro Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach

Drug metabolism and disposition, 2021-06, Vol.49 (6), p.470-478

2021

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Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.818-831

2019

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Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism

Biochemical pharmacology, 2018-10, Vol.156, p.32-42

2018

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Age-dependent Protein Abundance of Cytosolic Alcohol and Aldehyde Dehydrogenases in Human Liver

Drug metabolism and disposition, 2017-09, Vol.45 (9), p.1044-1048

2017

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In Vitro–to–In Vivo Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach

Drug metabolism and disposition, 2021-06, Vol.49 (6), p.470-478

2021

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Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.216-223

2017

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Fractional Contribution of UGT2B15 and UGT2B17 in Testosterone Glucuronidation in Human Liver Microsomes and Its Variability

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation

Cephalalgia, 2014-02, Vol.34 (2), p.136-147

2014

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Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes

Journal of hepatology, 2021-05, Vol.74 (5), p.1132-1144

2021

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Effect of TRPA1 activator allyl isothiocyanate (AITC) on rat dural and pial arteries

Pharmacological reports, 2019-08, Vol.71 (4), p.565-572

2019

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Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver

The Journal of pharmacology and experimental therapeutics, 2017-11, Vol.363 (2), p.265-274

2017

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Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex

Drug metabolism and disposition, 2018-06, Vol.46 (6), p.888-896

2018

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Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

The Promises of Quantitative Proteomics in Precision Medicine

Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study

Interindividual variability in hepatic expression of human sulfotransferase 2A1: Absolute quantification by LC-MS/MS proteomics and effect of ethnicity, genotype, age and gender

Critical Issues and Optimized Practices in Quantification of Protein Abundance Level to Determine Interindividual Variability in DMET Proteins by LC‐MS/MS Proteomics

Effect of oral testosterone on the plasma steroid metabolomics in humans

Quantitative Proteomics Reveals Changes in Transporter Protein Abundance in Liver, Kidney and Brain of Mice by Pregnancy

Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats

ADME QPrOmicstm mrm database: A repository of validated LC-MS/MS methods for ADME protein quantification

Critical issues and optimized practices in quantification of protein abundance level to determine inter-individual variability in DMET proteins by LC-MS/MS proteomics

Best Practices for Robust LC‐MS/MS Quantification of Drug Metabolizing Enzymes and Transporters to Predict Inter‐Individual Variability: Case Examples of Hepatic Cytosolic ADHs and ALDH1A1

PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice

In Vivo-to-In Vitro Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach

Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism

Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism

Age-dependent Protein Abundance of Cytosolic Alcohol and Aldehyde Dehydrogenases in Human Liver

In Vitro–to–In Vivo Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Fractional Contribution of UGT2B15 and UGT2B17 in Testosterone Glucuronidation in Human Liver Microsomes and Its Variability

Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation

Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes

Effect of TRPA1 activator allyl isothiocyanate (AITC) on rat dural and pial arteries

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver

Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex

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