UB Paderborn / Katalog / Suche / in CDI

Hepatic Steatosis and Thyroid Function Tests in Overweight and Obese Children

International Journal of Endocrinology, 2013-01, Vol.2013, p.381014-8

2013

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Acetyl‐CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

Hepatology (Baltimore, Md.), 2018-12, Vol.68 (6), p.2197-2211

2018

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Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study

Hepatology (Baltimore, Md.), 2017-08, Vol.66 (2), p.324-334

2017

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Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers

Neuropsychopharmacology (New York, N.Y.), 2022-02, Vol.47 (3), p.696-703

2022

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Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion

Scientific reports, 2019-03, Vol.9 (1), p.3803-3803, Article 3803

2019

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MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes

Diabetes (New York, N.Y.), 2014-09, Vol.63 (9), p.3141-3148

2014

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Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals

International Journal of Endocrinology, 2013-01, Vol.2013, p.870487-7

2013

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Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis[S]

Journal of lipid research, 2009-10, Vol.50 (10), p.2072-2082

2009

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Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model

Cellular and molecular gastroenterology and hepatology, 2018-01, Vol.5 (1), p.83-98.e10

2018

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A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes

Journal of lipid research, 2008-12, Vol.49 (12), p.2657-2663

2008

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901-P: Evaluation of the Analytical Performance of YSI 2900D Compared with YSI 2300 STAT Plus for Glucose Concentration Measurements

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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Whole-Body Glycolysis Measured by the Deuterated-Glucose Disposal Test Correlates Highly With Insulin Resistance In Vivo

Diabetes care, 2007-05, Vol.30 (5), p.1143-1149

2007

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Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption

The journal of clinical endocrinology and metabolism, 2020-04, Vol.105 (4), p.e1235-e1249

2020

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Potential Mechanisms Leading to the Abnormal Lipid Profile in Patients With Rheumatoid Arthritis Versus Healthy Volunteers and Reversal by Tofacitinib

Arthritis & rheumatology (Hoboken, N.J.), 2015-03, Vol.67 (3), p.616-625

2015

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Inhibition of fatty acid synthase with FT‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non‐alcoholic fatty liver disease: Results from two early‐phase randomized trials

Diabetes, obesity & metabolism, 2021-03, Vol.23 (3), p.700-710

2021

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low α-linolenic intake during early life increases adiposity in the adult guinea pig

Nutrition & metabolism, 2010-01, Vol.7 (1), p.8-8

2010

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Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

The Journal of clinical investigation, 2009-05, Vol.119 (5), p.1322-1334

2009

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Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood

Hepatology (Baltimore, Md.), 2017-01, Vol.65 (1), p.78-88

2017

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106-LB: Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Subjects with T1DM and T2DM

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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107-LB: Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Healthy Subjects (HS)

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease

The Journal of clinical investigation, 2021-12, Vol.131 (24), p.1-11

2021

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Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans

American journal of physiology: endocrinology and metabolism, 2018-07, Vol.315 (1), p.E126-E132

2018

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Intestinal bile acid sequestration improves glucose control by stimulating hepatic miR-182-5p in type 2 diabetes

American journal of physiology: Gastrointestinal and liver physiology, 2018-11, Vol.315 (5), p.G810-G823

2018

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Organic Anion Transporting Polypeptide Inhibition Dramatically Increases Plasma Exposure but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure of Firsocostat

Clinical pharmacology and therapeutics, 2021-05, Vol.109 (5), p.1334-1341

2021

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Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10512-10526

2014

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Hepatic Steatosis and Thyroid Function Tests in Overweight and Obese Children

Acetyl‐CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study

Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers

Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion

MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals

Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis[S]

Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model

A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes

901-P: Evaluation of the Analytical Performance of YSI 2900D Compared with YSI 2300 STAT Plus for Glucose Concentration Measurements

Whole-Body Glycolysis Measured by the Deuterated-Glucose Disposal Test Correlates Highly With Insulin Resistance In Vivo

Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption

Potential Mechanisms Leading to the Abnormal Lipid Profile in Patients With Rheumatoid Arthritis Versus Healthy Volunteers and Reversal by Tofacitinib

Inhibition of fatty acid synthase with FT‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non‐alcoholic fatty liver disease: Results from two early‐phase randomized trials

low α-linolenic intake during early life increases adiposity in the adult guinea pig

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood

106-LB: Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Subjects with T1DM and T2DM

107-LB: Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Healthy Subjects (HS)

Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease

Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans

Intestinal bile acid sequestration improves glucose control by stimulating hepatic miR-182-5p in type 2 diabetes

Organic Anion Transporting Polypeptide Inhibition Dramatically Increases Plasma Exposure but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure of Firsocostat

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes

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