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Evaluation of gastrointestinal drug supersaturation and precipitation: Strategies and issues

International journal of pharmaceutics, 2013-08, Vol.453 (1), p.25-35

2013

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Drug precipitation–permeation interplay: Supersaturation in an absorptive environment

European journal of pharmaceutics and biopharmaceutics, 2012-10, Vol.82 (2), p.424-428

2012

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Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation

European journal of pharmaceutics and biopharmaceutics, 2019-07, Vol.140, p.141-148

2019

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Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates

International journal of pharmaceutics, 2024-01, Vol.649, p.123654-123654, Article 123654

2024

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Small Oligomeric Micelles Based on End Group Modified mPEG−Oligocaprolactone with Monodisperse Hydrophobic Blocks

Macromolecules, 2007-01, Vol.40 (1), p.116-122

2007

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Usefulness of the BioGIT system in screening for differences in early exposure in the fasted state on an a priori basis

International journal of pharmaceutics, 2023-03, Vol.634, p.122670-122670, Article 122670

2023

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Screening for Differences in Early Exposure in the Fasted State with in Vitro Methodologies can be Challenging: Experience with the BioGIT System

Journal of pharmaceutical sciences, 2023-08, Vol.112 (8), p.2240-2248

2023

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Linking In Vitro Intrinsic Dissolution Rate and Thermodynamic Solubility with Pharmacokinetic Profiles of Bedaquiline Long-Acting Aqueous Microsuspensions in Rats

Molecular pharmaceutics, 2021-03, Vol.18 (3), p.952-965

2021

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Drug Supersaturation in Simulated Human Intestinal Fluids Representing Different Nutritional States

Journal of pharmaceutical sciences, 2010-11, Vol.99 (11), p.4525-4534

2010

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Current status and future opportunities for incorporation of dissolution data in PBPK modeling for pharmaceutical development and regulatory applications: OrBiTo consortium commentary

European journal of pharmaceutics and biopharmaceutics, 2020-10, Vol.155, p.55-68

2020

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Supersaturation in human gastric fluids

European journal of pharmaceutics and biopharmaceutics, 2012-05, Vol.81 (1), p.184-189

2012

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Preclinical Bioavailability Strategy for Decisions on Clinical Drug Formulation Development: An In Depth Analysis

Molecular pharmaceutics, 2018-07, Vol.15 (7), p.2633-2645

2018

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Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine

European journal of pharmaceutical sciences, 2013-04, Vol.49 (1), p.27-32

2013

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IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies

European journal of pharmaceutics and biopharmaceutics, 2020-11, Vol.156, p.50-63

2020

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IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

European journal of pharmaceutical sciences, 2017-01, Vol.96, p.610-625

2017

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Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs

Journal of pharmaceutical sciences, 2016-09, Vol.105 (9), p.2864-2872

2016

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IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

European journal of pharmaceutical sciences, 2017-01, Vol.96, p.626-642

2017

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IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

European journal of pharmaceutical sciences, 2017-01, Vol.96, p.598-609

2017

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Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

Molecular pharmaceutics, 2017-12, Vol.14 (12), p.4161-4169

2017

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Osteotomies around the knee alter alignment of the ankle and hindfoot: a systematic review of biomechanical and clinical studies

EFORT Open Reviews, 2023-11, Vol.8 (11), p.818-829

2023

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Evaluation of gastrointestinal drug supersaturation and precipitation: Strategies and issues

Drug precipitation–permeation interplay: Supersaturation in an absorptive environment

Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation

Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates

Small Oligomeric Micelles Based on End Group Modified mPEG−Oligocaprolactone with Monodisperse Hydrophobic Blocks

Usefulness of the BioGIT system in screening for differences in early exposure in the fasted state on an a priori basis

Screening for Differences in Early Exposure in the Fasted State with in Vitro Methodologies can be Challenging: Experience with the BioGIT System

Linking In Vitro Intrinsic Dissolution Rate and Thermodynamic Solubility with Pharmacokinetic Profiles of Bedaquiline Long-Acting Aqueous Microsuspensions in Rats

Drug Supersaturation in Simulated Human Intestinal Fluids Representing Different Nutritional States

Current status and future opportunities for incorporation of dissolution data in PBPK modeling for pharmaceutical development and regulatory applications: OrBiTo consortium commentary

Supersaturation in human gastric fluids

Preclinical Bioavailability Strategy for Decisions on Clinical Drug Formulation Development: An In Depth Analysis

Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

Osteotomies around the knee alter alignment of the ankle and hindfoot: a systematic review of biomechanical and clinical studies

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