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practical approach for exploration and modeling of the design space of a bacterial vaccine cultivation process

Biotechnology and bioengineering, 2009-10, Vol.104 (3), p.492-504

2009

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Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production

Engineering in life sciences, 2013-05, Vol.13 (3), p.212-223

2013

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Determination of amino acids using o-phthalaldehyde-2-mercaptoethanol derivatization effect of reaction conditions

Journal of Chromatography A, 1996-02, Vol.724 (1), p.159-167

1996

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Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes

Genome Biology, 2007-01, Vol.8 (7), p.R136-R136

2007

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Animal Cell Technology: Developments towards the 21st Century

2012

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Gene-expression-based quality scores indicate optimal harvest point in Bordetella pertussis cultivation for vaccine production

Biotechnology and bioengineering, 2009-08, Vol.103 (5), p.900-908

2009

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Modeling Neisseria meningitidis B metabolism at different specific growth rates

Biotechnology and bioengineering, 2008-12, Vol.101 (5), p.1022-1035

2008

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Scale-up for bulk production of vaccine against meningococcal disease

Vaccine, 2007-08, Vol.25 (34), p.6399-6408

2007

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Evaluation of a critical process parameter: Oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis

Biotechnology and bioengineering, 2009, Vol.102 (1), p.161-167

2009

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PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease

Vaccine, 2007-04, Vol.25 (16), p.2994-3000

2007

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Improving the cellular pertussis vaccine: Increased potency and consistency

Vaccine, 2008-01, Vol.26 (5), p.653-663

2008

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Gonococci and Meningococci: Epidemiology, Genetics, Immunochemistry and Pathogenesis

Reprinted from ANTONIE VAN LEEUWENHOEK, 54:6., 2012

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Effect of relevant culture parameters on Pertussis Toxin expression by Bordetella pertussis

Biologicals, 2006-09, Vol.34 (3), p.213-220

2006

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Animal Cell Technology

1, 1996

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Death rate in a small air-lift loop reactor of vero cells grown on solid microcarriers and in macroporous microcarriers

Cytotechnology (Dordrecht), 1997, Vol.23 (1-3), p.61-75

1997

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Fed-batch cultivation of Bordetella pertussis: Metabolism and Pertussis Toxin production

Biologicals, 2006-12, Vol.34 (4), p.289-297

2006

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Dual-substrate utilization by Bordetella pertussis

Applied microbiology and biotechnology, 2001-11, Vol.57 (4), p.489-493

2001

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Effect of dilution rate on growth, productivity, cell cycle and size, and shear sensitivity of a hybridoma cell in a continuous culture

Biotechnology and bioengineering, 1993-02, Vol.41 (4), p.429-439

1993

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Comparison of four bifunctional reagents for coupling peptides to proteins and the effect of the three moieties on the immunogenicity of the conjugates

Journal of immunological methods, 1989-06, Vol.120 (1), p.133-143

1989

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On-line estimation of the biomass activity during animal-cell cultivations

Biotechnology and bioengineering, 1996-07, Vol.51 (2), p.206-214

1996

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A combined cell-cycle and metabolic model for the growth of hybridoma cells in steady-state continuous culture

Biotechnology and bioengineering, 1995-10, Vol.48 (1), p.49-65

1995

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Effect of serum concentration on hybridoma viable cell density and production of monoclonal antibodies in cstrs and on shear sensitivity in air-lift loop reactors

Biotechnology and bioengineering, 1992-04, Vol.39 (9), p.891-897

1992

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A New WHO International Reference Reagent for Use in Potency Assays of Inactivated Poliomyelitis Vaccine

Biologicals, 1997-03, Vol.25 (1), p.59-64

1997

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Determination of amino acids using 0-phthalaldehyde-2-mercaptoethanol derivation. Effect of reaction conditions

Journal of Chromatography. A, Including electrophoresis and other separation methods, 1996, Vol.724

1996

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On-line estimation of the biomass activity during animal-cell cultivations

Biotechnology and bioengineering, 1996, Vol.50

1996

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practical approach for exploration and modeling of the design space of a bacterial vaccine cultivation process

Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production

Determination of amino acids using o-phthalaldehyde-2-mercaptoethanol derivatization effect of reaction conditions

Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes

Animal Cell Technology: Developments towards the 21st Century

Gene-expression-based quality scores indicate optimal harvest point in Bordetella pertussis cultivation for vaccine production

Modeling Neisseria meningitidis B metabolism at different specific growth rates

Scale-up for bulk production of vaccine against meningococcal disease

Evaluation of a critical process parameter: Oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis

PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease

Improving the cellular pertussis vaccine: Increased potency and consistency

Gonococci and Meningococci: Epidemiology, Genetics, Immunochemistry and Pathogenesis

Effect of relevant culture parameters on Pertussis Toxin expression by Bordetella pertussis

Animal Cell Technology

Death rate in a small air-lift loop reactor of vero cells grown on solid microcarriers and in macroporous microcarriers

Fed-batch cultivation of Bordetella pertussis: Metabolism and Pertussis Toxin production

Dual-substrate utilization by Bordetella pertussis

Effect of dilution rate on growth, productivity, cell cycle and size, and shear sensitivity of a hybridoma cell in a continuous culture

Comparison of four bifunctional reagents for coupling peptides to proteins and the effect of the three moieties on the immunogenicity of the conjugates

On-line estimation of the biomass activity during animal-cell cultivations

A combined cell-cycle and metabolic model for the growth of hybridoma cells in steady-state continuous culture

Effect of serum concentration on hybridoma viable cell density and production of monoclonal antibodies in cstrs and on shear sensitivity in air-lift loop reactors

A New WHO International Reference Reagent for Use in Potency Assays of Inactivated Poliomyelitis Vaccine

Determination of amino acids using 0-phthalaldehyde-2-mercaptoethanol derivation. Effect of reaction conditions

On-line estimation of the biomass activity during animal-cell cultivations

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