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Two-pore channels and disease

Biochimica et biophysica acta. Molecular cell research, 2018-11, Vol.1865 (11), p.1678-1686

2018

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Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers

Biochimica et biophysica acta. Molecular cell research, 2019-07, Vol.1866 (7), p.1151-1161

2019

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Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx

Journal of cell science, 2016-10, Vol.129 (20), p.3859-3867

2016

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Comparison of serum creatine kinase and aspartate aminotransferase activity in dogs with Neospora meningoencephalitis and noninfectious meningoencephalitis

Journal of veterinary internal medicine, 2022-01, Vol.36 (1), p.141-145

2022

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Raman Spectroscopy to Monitor Post-Translational Modifications and Degradation in Monoclonal Antibody Therapeutics

Analytical chemistry (Washington), 2020-08, Vol.92 (15), p.10381-10389

2020

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Enzymatic Late‐Stage Modifications: Better Late Than Never

Angewandte Chemie (International ed.), 2021-07, Vol.60 (31), p.16824-16855

International ed. in English, 2021

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An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

Cell reports (Cambridge), 2017-02, Vol.18 (7), p.1636-1645

2017

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Corticosteroid monotherapy versus combined cytarabine continuous rate infusion and corticosteroid therapy in dogs with meningoencephalitis of unknown origin: A blinded, randomized, controlled trial

Journal of veterinary internal medicine, 2024-05, Vol.38 (3), p.1618-1625

2024

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Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals

Journal of cell science, 2013-01, Vol.126 (Pt 1), p.60-66

2013

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A computational model of lysosome-ER Ca2+ microdomains

Journal of cell science, 2014-07, Vol.127 (Pt 13), p.2934-2943

2014

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Coupling acidic organelles with the ER through Ca2+ microdomains at membrane contact sites

Cell calcium (Edinburgh), 2015-10, Vol.58 (4), p.387-396

2015

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The lysosomotrope GPN mobilises Ca2+ from acidic organelles

Journal of cell science, 2021-03, Vol.134 (6)

2021

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Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

Journal of cell science, 2015-01, Vol.128 (2), p.232-238

2015

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Polymer hydrogels for glutathione-mediated protein release

European polymer journal, 2017-02, Vol.87, p.468-477

2017

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Quantification of protein glycation using vibrational spectroscopy

Analyst (London), 2020-05, Vol.145 (1), p.3686-3696

2020

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Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction

Angewandte Chemie International Edition, 2024-04, Vol.63 (18), p.e202314869-n/a

International ed. in English, 2024

Volltextzugriff (PDF)

Biochemical characterization of a glycoside hydrolase family 43 β-D-galactofuranosidase from the fungus Aspergillus niger

Enzyme and microbial technology, 2023-03, Vol.164, p.110170-110170, Article 110170

2023

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HCO+ Dissociative Recombination: A Significant Driver of Nonthermal Hydrogen Loss at Mars

Journal of geophysical research. Planets, 2023-01, Vol.128 (1), p.n/a

2023

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Endoplasmic reticulum and lysosomal Ca2+ stores are remodelled in GBA1 -linked Parkinson disease patient fibroblasts

Cell calcium (Edinburgh), 2016-01, Vol.59 (1), p.12-20

2016

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Nonthermal Hydrogen Loss at Mars: Contributions of Photochemical Mechanisms to Escape and Identification of Key Processes

Journal of geophysical research. Planets, 2023-08, Vol.128 (8), p.n/a

2023

Volltextzugriff (PDF)

Connecting Ca2+ and lysosomes to Parkinson disease

Messenger (Los Angeles, Calif.), 2016-06, Vol.5 (1-2), p.76-86

Kilpatrick, Bethan S

2016

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Connecting Ca 2+ and lysosomes to Parkinson disease

Messenger (Los Angeles, Calif.), 2016-06, Vol.5 (1-2), p.76-86

Kilpatrick, Bethan S

2016

Volltextzugriff (PDF)

Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction

Angewandte Chemie, 2024-04, Vol.136 (18), p.n/a

2024

Volltextzugriff (PDF)

An Endosomal NAADP-Sensitive Two-Pore Ca 2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

Cell reports (Cambridge), 2017-02, Vol.18 (7), p.1636-1645

2017

Volltextzugriff (PDF)

Methods for monitoring lysosomal morphology

Lysosomes and Lysosomal Diseases, 2015, Vol.126, p.1-19

2015

Volltextzugriff (PDF)

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Two-pore channels and disease

Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers

Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx

Comparison of serum creatine kinase and aspartate aminotransferase activity in dogs with Neospora meningoencephalitis and noninfectious meningoencephalitis

Raman Spectroscopy to Monitor Post-Translational Modifications and Degradation in Monoclonal Antibody Therapeutics

Enzymatic Late‐Stage Modifications: Better Late Than Never

An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

Corticosteroid monotherapy versus combined cytarabine continuous rate infusion and corticosteroid therapy in dogs with meningoencephalitis of unknown origin: A blinded, randomized, controlled trial

Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals

A computational model of lysosome-ER Ca2+ microdomains

Coupling acidic organelles with the ER through Ca2+ microdomains at membrane contact sites

The lysosomotrope GPN mobilises Ca2+ from acidic organelles

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

Polymer hydrogels for glutathione-mediated protein release

Quantification of protein glycation using vibrational spectroscopy

Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction

Biochemical characterization of a glycoside hydrolase family 43 β-D-galactofuranosidase from the fungus Aspergillus niger

HCO+ Dissociative Recombination: A Significant Driver of Nonthermal Hydrogen Loss at Mars

Endoplasmic reticulum and lysosomal Ca2+ stores are remodelled in GBA1 -linked Parkinson disease patient fibroblasts

Nonthermal Hydrogen Loss at Mars: Contributions of Photochemical Mechanisms to Escape and Identification of Key Processes

Connecting Ca2+ and lysosomes to Parkinson disease

Connecting Ca 2+ and lysosomes to Parkinson disease

Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction

An Endosomal NAADP-Sensitive Two-Pore Ca 2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

Methods for monitoring lysosomal morphology

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