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Non-Associative Learning in Larval Zebrafish

Neuropsychopharmacology (New York, N.Y.), 2008-04, Vol.33 (5), p.1206-1215

2008

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Circadian Programs of Transcriptional Activation, Signaling, and Protein Turnover Revealed by Microarray Analysis of Mammalian Cells

Current biology, 2002-04, Vol.12 (7), p.551-557

2002

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Epigenetic opportunities and challenges in cancer

Drug discovery today, 2010, Vol.15 (1), p.65-70

2010

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Epigenetic therapies for non-oncology indications

Drug discovery today, 2010-12, Vol.15 (23), p.1008-1014

2010

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Rapid Resetting of the Mammalian Circadian Clock

The Journal of neuroscience, 1999-01, Vol.19 (2), p.828-835

1999

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The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse

The Journal of pharmacology and experimental therapeutics, 2007-02, Vol.320 (2), p.552-558

2007

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The Epigenetics of Normal Pregnancy

Obstetric Medicine, 2013-03, Vol.6 (1), p.3-7

2013

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4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.280-284

2006

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Novel Orally Bioavailable γ-Secretase Inhibitors with Excellent in Vivo Activity

Journal of medicinal chemistry, 2009-06, Vol.52 (11), p.3441-3444

2009

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A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (2), p.373-378

2005

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A comparative assessment of γ-secretase activity in transgenic and non-transgenic rodent brain

Journal of neuroscience methods, 2006-10, Vol.157 (2), p.246-252

2006

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Epigenetic therapies for non-oncology indication

Drug discovery today, 2010, Vol.15 (23-24), p.1008-1014

2010

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Quantitative Measurement of Changes in Amyloid-β(40) in the Rat Brain and Cerebrospinal Fluid following Treatment with the γ-Secretase Inhibitor LY-411575 [ N 2 -[(2 S )-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]- N 1 -[(7 S )-5-methyl-6-oxo-6,7-dihydro-5 H -dibenzo[ b , d ]azepin-7-yl]-l-alaninamide]

The Journal of pharmacology and experimental therapeutics, 2005-05, Vol.313 (2), p.902-908

2005

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In Vivo Characterization of Aβ(40) Changes in Brain and Cerebrospinal Fluid Using the Novel γ-Secretase Inhibitor N -[ cis -4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the Rat

The Journal of pharmacology and experimental therapeutics, 2006-05, Vol.317 (2), p.786-790

2006

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In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the rat

The Journal of pharmacology and experimental therapeutics, 2006-05, Vol.317 (2), p.786

2006

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Quantitative measurement of changes in amyloid-beta(40) in the rat brain and cerebrospinal fluid following treatment with the gamma-secretase inhibitor LY-411575 [N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide]

The Journal of pharmacology and experimental therapeutics, 2005-05, Vol.313 (2), p.902

2005

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Application of microarray technology to identify novel components of the mammalian circadian clock

Nature genetics, 1999-11, Vol.23 (S3), p.42-42

1999

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Chapter 11 Entrainment of the circadian clock

Progress in Brain Research, 1996, Vol.111, p.147-174

1996

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Transfusion reactions: prevention, diagnosis, and treatment

The Lancet (British edition), 2016-12, Vol.388 (10061), p.2825-2836

2016

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Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Molecular cell, 2018-11, Vol.72 (3), p.510-524.e12

2018

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Martini 3: a general purpose force field for coarse-grained molecular dynamics

Nature methods, 2021-04, Vol.18 (4), p.382-388

2021

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FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga

The Journal of infectious diseases, 2016-10, Vol.214 (suppl 3), p.S319-S325

2016

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Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2

The Journal of clinical investigation, 2022-12, Vol.132 (24), p.1-16

2022

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Acute exercise alters brain glucose metabolism in aging and Alzheimer's disease

The Journal of physiology, 2024-09

2024

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A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

The New England journal of medicine, 2013-12, Vol.369 (24), p.2283-2293

2013

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Non-Associative Learning in Larval Zebrafish

Circadian Programs of Transcriptional Activation, Signaling, and Protein Turnover Revealed by Microarray Analysis of Mammalian Cells

Epigenetic opportunities and challenges in cancer

Epigenetic therapies for non-oncology indications

Rapid Resetting of the Mammalian Circadian Clock

The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse

The Epigenetics of Normal Pregnancy

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Novel Orally Bioavailable γ-Secretase Inhibitors with Excellent in Vivo Activity

A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

A comparative assessment of γ-secretase activity in transgenic and non-transgenic rodent brain

Epigenetic therapies for non-oncology indication

In Vivo Characterization of Aβ(40) Changes in Brain and Cerebrospinal Fluid Using the Novel γ-Secretase Inhibitor N -[ cis -4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the Rat

In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the rat

Quantitative measurement of changes in amyloid-beta(40) in the rat brain and cerebrospinal fluid following treatment with the gamma-secretase inhibitor LY-411575 [N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide]

Application of microarray technology to identify novel components of the mammalian circadian clock

Chapter 11 Entrainment of the circadian clock

Transfusion reactions: prevention, diagnosis, and treatment

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Martini 3: a general purpose force field for coarse-grained molecular dynamics

FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga

Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2

Acute exercise alters brain glucose metabolism in aging and Alzheimer's disease

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

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