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Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds

Toxicology letters, 2007-05, Vol.170 (3), p.214-222

2007

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Improving the applicability of (Q)SARs for percutaneous penetration in regulatory risk assessment

Human & experimental toxicology, 2008-04, Vol.27 (4), p.269-276

2008

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Molecular Aspects of Paracetamol-Induced Hepatotoxicity and its Mechanism-Based Prevention

Drug metabolism reviews, 1992, Vol.24 (3), p.367-407

1992

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Evaluation of three physiologically based pharmacokinetic (PBPK) modeling tools for emergency risk assessment after acute dichloromethane exposure

Toxicology letters, 2015-01, Vol.232 (1), p.21-27

2015

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Does EU legislation allow the use of the Benchmark dose (BMD) approach for risk assessment?

Regulatory toxicology and pharmacology, 2013-11, Vol.67 (2), p.182-188

2013

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Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors

Toxicology in vitro, 2011-04, Vol.25 (3), p.589-604

2011

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Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

Computational toxicology, 2019-02, Vol.9, p.61-72

2019

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Paracetamol (Acetaminophen)-Induced Toxicity: Molecular and Biochemical Mechanisms, Analogues and Protective Approaches

Critical reviews in toxicology, 2001, Vol.31 (1), p.55-138

2001

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Hydrogen atom abstraction of 3,5-disubstituted analogues of paracetamol by horseradish peroxidase and cytochrome P450

Xenobiotica, 1998-09, Vol.28 (9), p.855-875

1998

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Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol

Xenobiotica, 1996-06, Vol.26 (6), p.647-666

1996

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Toxicological profile for o-benzyl-p-chlorophenol

Journal of applied toxicology, 1998-07, Vol.18 (4), p.271-279

1998

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Non-tryptophan fluorescence of crystallins from normal and cataractous human lenses

Investigative ophthalmology & visual science, 1987-07, Vol.28 (7), p.1157-1163

1987

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Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes

Biochemical pharmacology, 1994-10, Vol.48 (8), p.1631-1640

1994

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Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment

Regulatory toxicology and pharmacology, 2004-02, Vol.39 (1), p.5-11

2004

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Cytotoxicity of paracetamol and 3,5-dihalogenated analogues: Role of cytochrome P-450 and formation of GSH conjugates and protein adducts

Toxicology in vitro, 1997-02, Vol.11 (1), p.9-19

1997

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The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity

Toxicology and applied pharmacology, 1989-09, Vol.100 (3), p.517-528

1989

Volltextzugriff (PDF)

Biotransformation of 1,2-dihydronaphthalene and 1,2-dihydroanthracene by rat liver microsomes and purified cytochromes P-450. Formation of arene hydrates of naphthalene and anthracene

Chemical research in toxicology, 1993-11, Vol.6 (6), p.808-812

1993

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Distribution of aromatic and fluorescent compounds within single human lenses

Experimental eye research, 1987-06, Vol.44 (6), p.817-824

1987

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Lanthionine, a protein cross-link in cataractous human lenses

Experimental eye research, 1987-05, Vol.44 (5), p.691-695

1987

Volltextzugriff (PDF)

Comparative and age-dependent aspects of crystallin size and distribution in human, rabbit, bovine, rat, chicken, duck, frog and dogfish lenses

Comparative biochemistry and physiology. B, Comparative biochemistry, 1983, Vol.76 (1), p.47

1983

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Age-related variations in the distribution of crystallins within the bovine lens

Experimental eye research, 1986-12, Vol.43 (6), p.1019-1030

1986

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The concentration-dependent aggregation of calf and human crystallins

Experimental eye research, 1986-12, Vol.43 (6), p.1135-1139

1986

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Variation in proportion and molecular weight of native crystallins from single human lenses upon aging and formation of nuclear cataract

Experimental eye research, 1983-01, Vol.37 (6), p.627-637

1983

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Size heterogeneity of the water-soluble proteins from human fetal lenses upon development

Developments in ophthalmology, 1989, Vol.17, p.128

1989

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A Comparison of Two Methods for the Determination of Thallium in Urine: Differential Pulse Anodic Stripping Voltammetry and Flameless Atomic Absorption Spectrophotometry

Annals of clinical biochemistry, 1983-09, Vol.20 (5), p.321-326

1983

Volltextzugriff (PDF)

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Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds

Improving the applicability of (Q)SARs for percutaneous penetration in regulatory risk assessment

Molecular Aspects of Paracetamol-Induced Hepatotoxicity and its Mechanism-Based Prevention

Evaluation of three physiologically based pharmacokinetic (PBPK) modeling tools for emergency risk assessment after acute dichloromethane exposure

Does EU legislation allow the use of the Benchmark dose (BMD) approach for risk assessment?

Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors

Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

Paracetamol (Acetaminophen)-Induced Toxicity: Molecular and Biochemical Mechanisms, Analogues and Protective Approaches

Hydrogen atom abstraction of 3,5-disubstituted analogues of paracetamol by horseradish peroxidase and cytochrome P450

Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol

Toxicological profile for o-benzyl-p-chlorophenol

Non-tryptophan fluorescence of crystallins from normal and cataractous human lenses

Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes

Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment

Cytotoxicity of paracetamol and 3,5-dihalogenated analogues: Role of cytochrome P-450 and formation of GSH conjugates and protein adducts

The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity

Biotransformation of 1,2-dihydronaphthalene and 1,2-dihydroanthracene by rat liver microsomes and purified cytochromes P-450. Formation of arene hydrates of naphthalene and anthracene

Distribution of aromatic and fluorescent compounds within single human lenses

Lanthionine, a protein cross-link in cataractous human lenses

Comparative and age-dependent aspects of crystallin size and distribution in human, rabbit, bovine, rat, chicken, duck, frog and dogfish lenses

Age-related variations in the distribution of crystallins within the bovine lens

The concentration-dependent aggregation of calf and human crystallins

Variation in proportion and molecular weight of native crystallins from single human lenses upon aging and formation of nuclear cataract

Size heterogeneity of the water-soluble proteins from human fetal lenses upon development

A Comparison of Two Methods for the Determination of Thallium in Urine: Differential Pulse Anodic Stripping Voltammetry and Flameless Atomic Absorption Spectrophotometry

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