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Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells

The Journal of biological chemistry, 1994-02, Vol.269 (8), p.6026-6030

1994

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Candidate ligand for the c‐kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors

The EMBO journal, 1990-10, Vol.9 (10), p.3287-3294

1990

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Molecular bases of dominant negative and loss of function mutations at the murine c‐kit/white spotting locus: W37, Wv, W41 and W

The EMBO journal, 1990-06, Vol.9 (6), p.1805-1813

1990

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Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation

Clinical cancer research, 2005-06, Vol.11 (11), p.4182-4190

2005

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Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells

The Journal of biological chemistry, 1993-07, Vol.268 (19), p.14189-14201

1993

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The kit-ligand (steel factor) and its receptor c-kit/W : pleiotropic roles in gametogenesis and melanogenesis

Development (Cambridge), 1993-01, Vol.119 (Supplement), p.125-137

1993

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A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

Nature cell biology, 2016-02, Vol.18 (2), p.157-167

2016

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Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand

Cell, 2002-05, Vol.109 (5), p.625-637

2002

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Differential roles of PI3‐kinase and Kit tyrosine 821 in Kit receptor‐mediated proliferation, survival and cell adhesion in mast cells

The EMBO journal, 1995-02, Vol.14 (3), p.473-483

1995

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Gonadal expression of c-kit encoded at the W locus of the mouse

Development (Cambridge), 1990-12, Vol.110 (4), p.1057-1069

1990

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Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

Molecular biology of the cell, 1992-03, Vol.3 (3), p.349-362

1992

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Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice

Genes & development, 1989-06, Vol.3 (6), p.816-826

1989

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c-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling

Molecular biology of the cell, 1997-05, Vol.8 (5), p.909-922

1997

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Role of kit-ligand in proliferation and suppression of apoptosis in mast cells : basis for radiosensitivity of white spotting and steel mutant mice

The Journal of experimental medicine, 1994-06, Vol.179 (6), p.1777-1787

1994

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Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C

The Journal of biological chemistry, 1994-12, Vol.269 (50), p.31991-31998

1994

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Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors

Clinical cancer research, 2003-08, Vol.9 (9), p.3329-3337

2003

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Gene Expression in Gastrointestinal Stromal Tumors Is Distinguished by KIT Genotype and Anatomic Site

Clinical cancer research, 2004-05, Vol.10 (10), p.3282-3290

2004

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Gastrointestinal Stromal Tumors in a Mouse Model by Targeted Mutation of the Kit Receptor Tyrosine Kinase

Proceedings of the National Academy of Sciences - PNAS, 2003-05, Vol.100 (11), p.6706-6711

2003

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Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus

The EMBO journal, 1988-04, Vol.7 (4), p.1003-1011

1988

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Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature

Journal of pediatric hematology/oncology, 2005-04, Vol.27 (4), p.179-187

2005

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Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

The EMBO journal, 1998-11, Vol.17 (21), p.6250-6262

1998

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Avian bic, a Gene Isolated from a Common Retroviral Site in Avian Leukosis Virus-Induced Lymphomas That Encodes a Noncoding RNA, Cooperates with c-myc in Lymphomagenesis and Erythroleukemogenesis

Journal of Virology, 2002-05, Vol.76 (9), p.4275-4286

2002

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Multiple gastrointestinal stromal tumors in type I neurofibromatosis: a pathologic and molecular study

Modern pathology, 2005-04, Vol.18 (4), p.475-484

2005

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W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis

Development (Cambridge), 1993-07, Vol.118 (3), p.705-717

1993

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Point mutation in Kit receptor tyrosine kinase reveals essential roles for Kit signaling in spermatogenesis and oogenesis without affecting other Kit responses

The EMBO journal, 2000-03, Vol.19 (6), p.1312-1326

2000

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Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells

Candidate ligand for the c‐kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors

Molecular bases of dominant negative and loss of function mutations at the murine c‐kit/white spotting locus: W37, Wv, W41 and W

Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation

Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells

The kit-ligand (steel factor) and its receptor c-kit/W : pleiotropic roles in gametogenesis and melanogenesis

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand

Differential roles of PI3‐kinase and Kit tyrosine 821 in Kit receptor‐mediated proliferation, survival and cell adhesion in mast cells

Gonadal expression of c-kit encoded at the W locus of the mouse

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice

c-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling

Role of kit-ligand in proliferation and suppression of apoptosis in mast cells : basis for radiosensitivity of white spotting and steel mutant mice

Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C

Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors

Gene Expression in Gastrointestinal Stromal Tumors Is Distinguished by KIT Genotype and Anatomic Site

Gastrointestinal Stromal Tumors in a Mouse Model by Targeted Mutation of the Kit Receptor Tyrosine Kinase

Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus

Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

Avian bic, a Gene Isolated from a Common Retroviral Site in Avian Leukosis Virus-Induced Lymphomas That Encodes a Noncoding RNA, Cooperates with c-myc in Lymphomagenesis and Erythroleukemogenesis

Multiple gastrointestinal stromal tumors in type I neurofibromatosis: a pathologic and molecular study

W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis

Point mutation in Kit receptor tyrosine kinase reveals essential roles for Kit signaling in spermatogenesis and oogenesis without affecting other Kit responses

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