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Novel Phthalazin-1(2H)-One Derivatives Displaying a Dithiocarbamate Moiety as Potential Anticancer Agents

Molecules (Basel, Switzerland), 2022-11, Vol.27 (23), p.8115

2022

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Phthalazin-1(2H)-one as a remarkable scaffold in drug discovery

European journal of medicinal chemistry, 2015-06, Vol.97, p.462-482

2015

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The New Pharmacological Chaperones PBXs Increase α-Galactosidase A Activity in Fabry Disease Cellular Models

Biomolecules (Basel, Switzerland), 2021-12, Vol.11 (12), p.1856

2021

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Stereoselective synthesis of 2,3,4-trisubstituted tetrahydrothiophenes

Tetrahedron letters, 2009-12, Vol.50 (50), p.6941-6943

2009

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4-[(tert-Butyl-diphenyl-sil-yloxy)meth-yl]pyridazin-3(2H)-one

Acta crystallographica. Section E, Structure reports online, 2013-12, Vol.69 (Pt 12), p.o1859-o1860

2013

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2-Benzyl-5-methoxyisoindoline-1,3-dione

Acta crystallographica. Section E, Structure reports online, 2013-10, Vol.69 (10), p.o1594-o1595

2013

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Stilbene-pyridazinone hybrids: design, synthesis and in vitro antiplatelet activity screening

Bioorganic chemistry, 2024-09, Vol.150, p.107615, Article 107615

2024

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Design and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality

Organic & biomolecular chemistry, 2005-05, Vol.3 (10), p.2016-2025

2005

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Geometry, topology, and atom-weights assembly descriptors to predicting A1 adenosine receptors agonists

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (10), p.2641-2645

2005

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Molecular recognition at purine and pyrimidine nucleotide (P2) receptors

Current topics in medicinal chemistry, 2004-01, Vol.4 (8), p.805-819

2004

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Recent advances in the synthesis of phthalazin-1(2H)-one core as a relevant pharmacophore in medicinal chemistry

European journal of medicinal chemistry, 2019-01, Vol.161, p.468-478

2019

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PBXs: New pharmacological chaperones to increase α-galactosidase A activity in Fabry disease cellular models

Molecular genetics and metabolism, 2023-02, Vol.138 (2), p.107255, Article 107255

2023

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Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

European journal of medicinal chemistry, 2017-10, Vol.139, p.1-11

2017

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Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson’s disease therapy

Bioorganic chemistry, 2020-11, Vol.104, p.104203, Article 104203

2020

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Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2H)-one derivatives as novel cholinesterase inhibitors

RSC advances, 2016-01, Vol.6 (52), p.46170-46185

2016

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Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors

Bioorganic chemistry, 2021-10, Vol.115, p.105203-105203, Article 105203

2021

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Novel compounds of hybrid structure pyridazinone–coumarin as potent inhibitors of platelet aggregation

Future medicinal chemistry, 2019-08, Vol.11 (16), p.2051-2062

2019

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New platelet aggregation inhibitors based on pyridazinone moiety

European journal of medicinal chemistry, 2015-04, Vol.94, p.113-122

2015

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Novel Pyridazin-3(2H)‑one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity

ACS medicinal chemistry letters, 2022-03, Vol.13 (3), p.463-469

2022

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Synthesis of a Greek tobacco lactonic natural product and its analogues

Tetrahedron letters, 2012-08, Vol.53 (33), p.4293-4295

2012

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New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6624-6627

2010

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Synthesis and cytostatic activity of purine nucleosides derivatives of allofuranose

European journal of medicinal chemistry, 2010-12, Vol.45 (12), p.6114-6119

2010

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New antiplatelet and vasorelaxant agents based on the pyridazinone moiety (1054.6)

The FASEB journal, 2014-04, Vol.28 (S1), p.n/a

2014

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Antiaggregatory activity in human platelets of potent antagonists of the P2Y1 receptor

Biochemical pharmacology, 2004-11, Vol.68 (10), p.1995-2002

2004

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Complete assignment of the (1)H and (13)C NMR spectra of cis and trans isonucleoside derivatives of purine with a tetrahydropyran ring

Magnetic resonance in chemistry, 2010-06, Vol.48 (6), p.483-485

2010

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Novel Phthalazin-1(2H)-One Derivatives Displaying a Dithiocarbamate Moiety as Potential Anticancer Agents

Phthalazin-1(2H)-one as a remarkable scaffold in drug discovery

The New Pharmacological Chaperones PBXs Increase α-Galactosidase A Activity in Fabry Disease Cellular Models

Stereoselective synthesis of 2,3,4-trisubstituted tetrahydrothiophenes

4-[(tert-Butyl-diphenyl-sil-yloxy)meth-yl]pyridazin-3(2H)-one

2-Benzyl-5-methoxyisoindoline-1,3-dione

Stilbene-pyridazinone hybrids: design, synthesis and in vitro antiplatelet activity screening

Design and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality

Geometry, topology, and atom-weights assembly descriptors to predicting A1 adenosine receptors agonists

Molecular recognition at purine and pyrimidine nucleotide (P2) receptors

Recent advances in the synthesis of phthalazin-1(2H)-one core as a relevant pharmacophore in medicinal chemistry

PBXs: New pharmacological chaperones to increase α-galactosidase A activity in Fabry disease cellular models

Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson’s disease therapy

Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2H)-one derivatives as novel cholinesterase inhibitors

Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors

Novel compounds of hybrid structure pyridazinone–coumarin as potent inhibitors of platelet aggregation

New platelet aggregation inhibitors based on pyridazinone moiety

Novel Pyridazin-3(2H)‑one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity

Synthesis of a Greek tobacco lactonic natural product and its analogues

New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities

Synthesis and cytostatic activity of purine nucleosides derivatives of allofuranose

New antiplatelet and vasorelaxant agents based on the pyridazinone moiety (1054.6)

Antiaggregatory activity in human platelets of potent antagonists of the P2Y1 receptor

Complete assignment of the (1)H and (13)C NMR spectra of cis and trans isonucleoside derivatives of purine with a tetrahydropyran ring

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