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Discovery and Pharmacological Evaluation of a Diphenethylamine Derivative (HS665), a Highly Potent and Selective κ Opioid Receptor Agonist

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10302-10306

2012

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Structural determinants of diphenethylamines for interaction with the κ opioid receptor: Synthesis, pharmacology and molecular modeling studies

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4769-4774

2016

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Comparative Molecular Field Analysis of the Binding of the Stereoisomers of Fenoterol and Fenoterol Derivatives to the β2 Adrenergic Receptor

Journal of medicinal chemistry, 2007-06, Vol.50 (12), p.2903-2915

2007

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Synthesis and Pharmacological Activities of 6-Glycine Substituted 14-Phenylpropoxymorphinans, a Novel Class of Opioids with High Opioid Receptor Affinities and Antinociceptive Potencies

Journal of medicinal chemistry, 2011-02, Vol.54 (4), p.980-988

2011

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Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1

The Journal of pharmacology and experimental therapeutics, 1997-11, Vol.283 (2), p.735

1997

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Discovery and biological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist

BMC pharmacology & toxicology, 2012-09, Vol.13 (S1), p.A43-A43, Article A43

2012

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 21. Novel 4-Alkoxy and 14-Phenylpropoxy Derivatives of the μ Opioid Receptor Antagonist Cyprodime

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.3242-3247

2004

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Identification of novel ligands interacting with kappa opioid receptors

BMC pharmacology, 2011-09, Vol.11 (S2), p.A15-A15, Article A15

2011

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Determination of activity for nociceptin in the mouse vas deferens

European journal of pharmacology, 1996-04, Vol.302 (1), p.R1-R2

1996

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Synthesis and Biological Evaluation of 14‐Alkoxymorphinans. Part 19: Effect of 14‐ O ‐Benzylation on the Opioid Receptor Affinity and Antagonist Potency of Naltrexone

Helvetica chimica acta, 2003-01, Vol.86 (7), p.2335-2341

2003

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 19

Helvetica chimica acta, 2003-07, Vol.86 (7), p.2335-2341

2003

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Synthesis and Biological Evaluation of α- and β-6-Amido Derivatives of 17-Cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxymorphinan: Potential Alcohol-Cessation Agents

Journal of medicinal chemistry, 2008-03, Vol.51 (6), p.1913-1924

2008

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Structural Determinants of Opioid Activity in the Orvinols and Related Structures. Ethers of 7,8-Cyclopenta-Fused Analogs of Buprenorphine

Helvetica chimica acta, 2000-04, Vol.83 (4), p.687-693

2000

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Synthesis and biological evaluation of alpha- and beta-6-amido derivatives of 17-cyclopropylmethyl-3, 14beta-dihydroxy-4, 5alpha-epoxymorphinan: potential alcohol-cessation agents

Journal of medicinal chemistry, 2008-03, Vol.51 (6), p.1913

2008

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 15. Novel δ opiod receptor antagonists with high affinity and selectivity in the 14-alkoxy-substituted indolomorphinan series

Helvetica chimica acta, 1998, Vol.81 (5-8), p.1064-1069

1998

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Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor

Journal of medicinal chemistry, 2007-06, Vol.50 (12), p.2903-2915

2007

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Comparative Molecular Field Analysis of the Binding of the Stereoisomers of Fenoterol and Fenoterol Derivatives to the β 2 Adrenergic Receptor

Journal of medicinal chemistry, 2007-06, Vol.50 (12), p.2903-2915

2007

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Comparison of κ2-opioid receptors in guinea pig brain and guinea pig ileum membranes

European journal of pharmacology, 1993-02, Vol.231 (2), p.251-258

1993

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Binding, pharmacological and immunological profiles of the δ-selective opioid receptor antagonist HS 378

Life sciences (1973), 2001-08, Vol.69 (15), p.1775-1782

2001

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Synthesis and characterization of substituted benzoylhydrazones of naloxone

Synapse (New York, N.Y.), 1996-10, Vol.24 (2), p.193-201

1996

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Synthesis and biological evaluation of 14-alkoxymorphinans. 21. Novel 4-alkoxy and 14-phenylpropoxy derivatives of the μ opioid receptor antagonist cvprodime

Journal of medicinal chemistry, 2004, Vol.47 (12), p.3242-3247

2004

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Structural Determinants of Opioid Activity in the Orvinols and Related Structures: Ethers of Orvinol and Isoorvinol

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1852-1857

2000

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Opioid receptor assays

Current Protocols in Pharmacology, 2001-05, Vol.Chapter 4 (1), p.Unit4.8-Unit4.8

Berzetei-Gurske, I

2001

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 19. Effect of 14-O-Benzylation on the Opioid Receptor Affinity and Antagonist Potency of Naltrexone

ChemInform, 2003-10, Vol.34 (41), p.no-no

2003

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Characterization of rabbit ear artery opioid receptors using a δ-selective agonist and antagonist

European journal of pharmacology, 1987-07, Vol.139 (1), p.61-66

1987

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Discovery and Pharmacological Evaluation of a Diphenethylamine Derivative (HS665), a Highly Potent and Selective κ Opioid Receptor Agonist

Structural determinants of diphenethylamines for interaction with the κ opioid receptor: Synthesis, pharmacology and molecular modeling studies

Comparative Molecular Field Analysis of the Binding of the Stereoisomers of Fenoterol and Fenoterol Derivatives to the β2 Adrenergic Receptor

Synthesis and Pharmacological Activities of 6-Glycine Substituted 14-Phenylpropoxymorphinans, a Novel Class of Opioids with High Opioid Receptor Affinities and Antinociceptive Potencies

Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1

Discovery and biological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 21. Novel 4-Alkoxy and 14-Phenylpropoxy Derivatives of the μ Opioid Receptor Antagonist Cyprodime

Identification of novel ligands interacting with kappa opioid receptors

Determination of activity for nociceptin in the mouse vas deferens

Synthesis and Biological Evaluation of 14‐Alkoxymorphinans. Part 19: Effect of 14‐ O ‐Benzylation on the Opioid Receptor Affinity and Antagonist Potency of Naltrexone

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 19

Synthesis and Biological Evaluation of α- and β-6-Amido Derivatives of 17-Cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxymorphinan: Potential Alcohol-Cessation Agents

Structural Determinants of Opioid Activity in the Orvinols and Related Structures. Ethers of 7,8-Cyclopenta-Fused Analogs of Buprenorphine

Synthesis and biological evaluation of alpha- and beta-6-amido derivatives of 17-cyclopropylmethyl-3, 14beta-dihydroxy-4, 5alpha-epoxymorphinan: potential alcohol-cessation agents

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 15. Novel δ opiod receptor antagonists with high affinity and selectivity in the 14-alkoxy-substituted indolomorphinan series

Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor

Comparative Molecular Field Analysis of the Binding of the Stereoisomers of Fenoterol and Fenoterol Derivatives to the β 2 Adrenergic Receptor

Comparison of κ2-opioid receptors in guinea pig brain and guinea pig ileum membranes

Binding, pharmacological and immunological profiles of the δ-selective opioid receptor antagonist HS 378

Synthesis and characterization of substituted benzoylhydrazones of naloxone

Synthesis and biological evaluation of 14-alkoxymorphinans. 21. Novel 4-alkoxy and 14-phenylpropoxy derivatives of the μ opioid receptor antagonist cvprodime

Structural Determinants of Opioid Activity in the Orvinols and Related Structures: Ethers of Orvinol and Isoorvinol

Opioid receptor assays

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 19. Effect of 14-O-Benzylation on the Opioid Receptor Affinity and Antagonist Potency of Naltrexone

Characterization of rabbit ear artery opioid receptors using a δ-selective agonist and antagonist

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