UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment

International journal of molecular sciences, 2021-05, Vol.22 (10), p.5262

2021

Volltextzugriff (PDF)

Combined in vivo effect of N-acylethanolamine-hydrolyzing acid amidase and glycogen synthase kinase-3β inhibition to treat multiple sclerosis

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116677, Article 116677

2024

Volltextzugriff (PDF)

Editorial: Protein-Protein Interactions: Drug Discovery for the Future

Frontiers in chemistry, 2021-11, Vol.9, p.811190-811190

2021

Volltextzugriff (PDF)

Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6917-6934

2013

Volltextzugriff (PDF)

A Novel Metal Iodide Promoted Three-Component Synthesis of Substituted Pyrrolidines

Organic letters, 2002-09, Vol.4 (18), p.3147-3150

2002

Volltextzugriff (PDF)

A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators

European respiratory review, 2018-06, Vol.27 (148), p.170124

2018

Volltextzugriff (PDF)

Synthesis, Structure-Activity, and Structure-Stability Relationships of 2-Substituted-N-(4-oxo-3-oxetanyl) N-Acylethanolamine Acid Amidase (NAAA) Inhibitors

ChemMedChem, 2014-02, Vol.9 (2), p.323-336

2014

Volltextzugriff (PDF)

Synthesis, Structure−Activity Relationships, and Characterization of Novel Nonsteroidal and Selective Androgen Receptor Modulators

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.7186-7191

2009

Volltextzugriff (PDF)

Copper Phosphoramidite Catalyzed Enantioselective Ring-Opening of Oxabicyclic Alkenes: Remarkable Reversal of Stereocontrol

Organic letters, 2002-08, Vol.4 (16), p.2703-2705

2002

Volltextzugriff (PDF)

Highly Enantioselective Regiodivergent and Catalytic Parallel Kinetic Resolution

Angewandte Chemie (International ed.), 2001-03, Vol.40 (5), p.930-932

2001

Volltextzugriff (PDF)

Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N‑Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13327-13355

2021

Volltextzugriff (PDF)

Inhibition of N-acylethanolamine-hydrolyzing acid amidase reduces T cell infiltration in a mouse model of multiple sclerosis

Pharmacological research, 2021-10, Vol.172, p.105816-105816, Article 105816

2021

Volltextzugriff (PDF)

A Combinatorial Scaffold Approach Based upon a Multicomponent Reaction

Organic letters, 2003-05, Vol.5 (9), p.1551-1554

2003

Volltextzugriff (PDF)

Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro‑1H‑pyrido[4,3‑b]indoles as a Novel Class of CFTR Potentiators

Journal of medicinal chemistry, 2020-10, Vol.63 (19), p.11169-11194

2020

Volltextzugriff (PDF)

Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure–activity relationship (SAR) studies

European journal of medicinal chemistry, 2016-03, Vol.111, p.138-159

2016

Volltextzugriff (PDF)

Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H -pyrido[4,3- b ]indoles as a Novel Class of CFTR Potentiators

Journal of medicinal chemistry, 2020-10, Vol.63 (19), p.11169-11194

2020

Volltextzugriff (PDF)

Discovery of a New Class of Highly Potent Inhibitors of Acid Ceramidase: Synthesis and Structure–Activity Relationship (SAR)

Journal of medicinal chemistry, 2013-05, Vol.56 (9), p.3518-3530

2013

Volltextzugriff (PDF)

A Potent Systemically Active N‑Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation

ACS chemical biology, 2015-08, Vol.10 (8), p.1838-1846

2015

Volltextzugriff (PDF)

Activity-Based Probe for N‑Acylethanolamine Acid Amidase

ACS chemical biology, 2015-09, Vol.10 (9), p.2057-2064

2015

Volltextzugriff (PDF)

2-Oxopyridine-1-carboxylates, highly reactive carbamoylating agents of β-hydroxy α-aminoacids

Tetrahedron letters, 2015-05, Vol.56 (22), p.2887-2891

2015

Volltextzugriff (PDF)

Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign

European journal of medicinal chemistry, 2020-03, Vol.189, p.112047-112047, Article 112047

2020

Volltextzugriff (PDF)

Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure–Activity Relationships

Synthesis (Stuttgart), 2016-09, Vol.48 (17), p.2739-2756

2016

Volltextzugriff (PDF)

Synthesis, Biological Evaluation, and 3D QSAR Study of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters as N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.10101-10111

2014

Volltextzugriff (PDF)

3-Aminoazetidin-2-one Derivatives as N-Acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration

ChemMedChem, 2014-07, Vol.9 (7), p.1602-1614

2014

Volltextzugriff (PDF)

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel

Science advances, 2020-02, Vol.6 (8), p.eaay9669-eaay9669

2020

Volltextzugriff (PDF)

1 – 25 von 120

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(106)
Mit Volltextzugriff
(113)

Publikationsform

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(69)
Life Sciences & Biomedicine
(51)
Humans
(31)
Physical Sciences
(16)
Animals
(15)
Chemistry
(15)
Pharmacology & Pharmacy
(15)
Female
(13)
Chemistry, Medicinal
(11)
Chemistry, Organic
(11)
Male
(11)
Amidohydrolases - Antagonists & Inhibitors
(10)
Structure-Activity Relationship
(10)
Middle Aged
(9)
Enzyme Inhibitors - Pharmacology
(8)
Surgery
(8)
Mice
(7)
Rats
(7)
Adult
(6)
Aged
(6)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment

Combined in vivo effect of N-acylethanolamine-hydrolyzing acid amidase and glycogen synthase kinase-3β inhibition to treat multiple sclerosis

Editorial: Protein-Protein Interactions: Drug Discovery for the Future

Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

A Novel Metal Iodide Promoted Three-Component Synthesis of Substituted Pyrrolidines

A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators

Synthesis, Structure-Activity, and Structure-Stability Relationships of 2-Substituted-N-(4-oxo-3-oxetanyl) N-Acylethanolamine Acid Amidase (NAAA) Inhibitors

Synthesis, Structure−Activity Relationships, and Characterization of Novel Nonsteroidal and Selective Androgen Receptor Modulators

Copper Phosphoramidite Catalyzed Enantioselective Ring-Opening of Oxabicyclic Alkenes: Remarkable Reversal of Stereocontrol

Highly Enantioselective Regiodivergent and Catalytic Parallel Kinetic Resolution

Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N‑Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration

Inhibition of N-acylethanolamine-hydrolyzing acid amidase reduces T cell infiltration in a mouse model of multiple sclerosis

A Combinatorial Scaffold Approach Based upon a Multicomponent Reaction

Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro‑1H‑pyrido[4,3‑b]indoles as a Novel Class of CFTR Potentiators

Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure–activity relationship (SAR) studies

Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H -pyrido[4,3- b ]indoles as a Novel Class of CFTR Potentiators

Discovery of a New Class of Highly Potent Inhibitors of Acid Ceramidase: Synthesis and Structure–Activity Relationship (SAR)

A Potent Systemically Active N‑Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation

Activity-Based Probe for N‑Acylethanolamine Acid Amidase

2-Oxopyridine-1-carboxylates, highly reactive carbamoylating agents of β-hydroxy α-aminoacids

Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign

Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure–Activity Relationships

Synthesis, Biological Evaluation, and 3D QSAR Study of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters as N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

3-Aminoazetidin-2-one Derivatives as N-Acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel

Suchergebnisse filtern