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Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations

PLoS genetics, 2023-08, Vol.19 (8), p.e1010903-e1010903

2023

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A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome

Molecular and cellular biology, 2018-01, Vol.38 (1)

2018

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Dinoflagellate tandem array gene transcripts are highly conserved and not polycistronic

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (39), p.15793-15798

2012

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Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways

eLife, 2019-12, Vol.8

2019

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Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells

PloS one, 2013-10, Vol.8 (10), p.e77390

2013

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UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

Cell stem cell, 2021-01, Vol.28 (1), p.48-62.e6

2021

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Abstract 2635: Targeting virus-induced vulnerabilities using synthetic lethality as a new class of host-based antivirals

The Journal of biological chemistry, 2023, Vol.299 (3), p.103343, Article 103343

2023

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Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development

Genetics (Austin), 2020-04, Vol.214 (4), p.1103-1120

2020

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Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells

Molecular cell, 2020-09, Vol.79 (5), p.846-856.e8

2020

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Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

Molecular cell, 2023-11, Vol.83 (22), p.4078-4092.e6

2023

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A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Aging cell, 2021-04, Vol.20 (4), p.e13331-n/a

2021

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Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Blood, 2022-11, Vol.140 (Supplement 1), p.8825-8826

2022

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A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7

Antioxidants & redox signaling, 2018-01, Vol.28 (1), p.62-77

2018

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Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

The Journal of cell biology, 2022-11, Vol.221 (11), p.1

2022

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Abstract C4: TLN-4601 is a novel tumor selective pro-apoptotic agent acting independently of Bax, Bak or Bcl-2 expression

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.C4-C4

2009

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3082 – EXPLORING GLUCOCORTICOID SENSITIVITY MODULATORS IN HUMAN ACUTE MYELOID LEUKEMIA

Experimental hematology, 2020-08, Vol.88, p.S63-S63

2020

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Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids

Blood, 2018-11, Vol.132 (Supplement 1), p.4675-4675

2018

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Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex

Science advances, 2021-10, Vol.7 (44), p.eabi5797

2021

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S-Phase and M-Phase Timing Are under Independent Circadian Control in the Dinoflagellate Lingulodinium

Journal of biological rhythms, 2008-10, Vol.23 (5), p.400-408

2008

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Abstract 3058: miRNA networks mediate the tumor suppressive function of FOXO proteins

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.3058-3058

2013

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Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP

Apoptosis (London), 2013-10, Vol.18 (10), p.1154-1162

2013

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299 - The Peroxidase PRDX1 Is Regulating FOXO3 Signaling in a Redox Dependent Manner

Free radical biology & medicine, 2014-11, Vol.76, p.S127-S127

2014

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The Peroxidase PRDX1 Is Regulating FOXO3 Signaling in a Redox Dependent Manner

Free radical biology & medicine, 2014-11, Vol.76, p.S127

2014

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Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations

A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome

Dinoflagellate tandem array gene transcripts are highly conserved and not polycistronic

Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways

Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

Abstract 2635: Targeting virus-induced vulnerabilities using synthetic lethality as a new class of host-based antivirals

Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development

Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells

Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

Abstract C4: TLN-4601 is a novel tumor selective pro-apoptotic agent acting independently of Bax, Bak or Bcl-2 expression

3082 – EXPLORING GLUCOCORTICOID SENSITIVITY MODULATORS IN HUMAN ACUTE MYELOID LEUKEMIA

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids

Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

S-Phase and M-Phase Timing Are under Independent Circadian Control in the Dinoflagellate Lingulodinium

Abstract 3058: miRNA networks mediate the tumor suppressive function of FOXO proteins

Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP

299 - The Peroxidase PRDX1 Is Regulating FOXO3 Signaling in a Redox Dependent Manner

The Peroxidase PRDX1 Is Regulating FOXO3 Signaling in a Redox Dependent Manner

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