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Engineered RBCs Encapsulating Antigen Induce Multi-Modal Antigen-Specific Tolerance and Protect Against Type 1 Diabetes

Frontiers in immunology, 2022-04, Vol.13, p.869669-869669

2022

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Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice

Frontiers in immunology, 2022-10, Vol.13, p.1015585-1015585

2022

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693 SQZ-AAC-HPV-101: initial data from a phase I dose escalation/expansion study of SQZ-AAC-HPV, a red blood cell-based therapeutic cancer vaccine for HPV16+ solid tumors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A785-A785

2023

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692 COMMANDER-001: safety data from a phase I/II dose escalation/expansion study of SQZ-eAPC-HPV, a cell-based mRNA therapeutic cancer vaccine for HPV16+ solid tumors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A784-A784

2023

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594 SQZ-PBMC-HPV-101: Increased overall survival in a subset of patients with recurrent, locally advanced, or metastatic HPV16+ tumors treated with cell-based vaccine, SQZ-PBMC-HPV

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A676-A676

2023

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165 Activating antigen carriers generated with microfluidics cell squeezing drive effective anti-tumor responses

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A98-A99

2020

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Porous PLGA microparticles: AI-700, an intravenously administered ultrasound contrast agent for use in echocardiography

Journal of controlled release, 2005-11, Vol.108 (1), p.21-32

2005

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156 RBC-derived, activating antigen carriers (SQZ AACs) prime potent T cell responses and drive tumor regression in vivo

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A166-A166

2021

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211 SQZ™ eAPCs generated from PBMCs by delivery of multiple mRNAs encoding for antigens, costimulatory proteins, and engineered cytokines

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A224-A224

2021

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Local anesthetics and mode of delivery : Bupivacaine versus ropivacaine versus levobupivacaine

Anesthesia and analgesia, 2007-09, Vol.105 (3), p.756-763

2007

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170 Microfluidics cell squeezing enables potent cellular vaccines in murine models through direct cytosolic loading and direct CD8 T cell priming

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A102-A102

2020

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Noncompaction Cardiomyopathy: Case Report and Echocardiographic Findings

Journal of cardiothoracic and vascular anesthesia, 2009-04, Vol.23 (2), p.200-202

2009

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Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (46), p.E10907-E10914

2018

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Abstract 1524: Peripheral blood mononuclear cells engineered via microfluidic Cell Squeeze® technology to generate APCs that drive mutant-KRas-specific CD8+ T cell responses

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1524-1524

2021

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Formation of microparticulate protein powder using a supercritical fluid antisolvent

Biotechnology and bioengineering, 1993-02, Vol.41 (3), p.341-346

1993

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Abstract 1523: Cell Squeeze® delivery of antigen-encoding mRNA enables human PBMCs to drive antigen-specific CD8+ T cell responses for diverse clinical applications

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1523-1523

2021

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Abstract 1525: Enhancing potency of antigen presenting cells via signal 2/3 mRNA engineering through Cell Squeeze® technology

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1525-1525

2021

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Abstract 1445: Tumor-specific T cell engineering for enhanced effector function via microfluidic delivery of bioactive molecules

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1445-1445

2019

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Abstract 3187: Engineering a new generation of cell therapies for solid tumor oncology using the SQZ platform

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3187-3187

2019

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1743-P: Engineering Erythrocytes with the SQZ Cell Therapy Platform to Enhance Immunotolerance

Diabetes (New York, N.Y.), 2019-06, Vol.68 (Supplement_1)

2019

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573. Vector Free Genome Editing of Immune Cells for Cell Therapy

Molecular therapy, 2016-05, Vol.24, p.S229-S229

2016

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The automated malnutrition assessment

Nutrition (Burbank, Los Angeles County, Calif.), 2013, Vol.29 (1), p.113-121

2013

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Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid tumors: SQZ-PBMC-HPV-101

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.2536-2536

2021

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Subarachnoid Small-Dose Bupivacaine Versus Lidocaine for Cervical Cerclage

Anesthesia and analgesia, 2003-07, Vol.97 (1), p.56-61

2003

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Vector-Free Engineering of Antigen Presenting Cells for Adoptive Immunotherapies for the Treatment of Cancer

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.73-73.18

2017

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Engineered RBCs Encapsulating Antigen Induce Multi-Modal Antigen-Specific Tolerance and Protect Against Type 1 Diabetes

Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice

693 SQZ-AAC-HPV-101: initial data from a phase I dose escalation/expansion study of SQZ-AAC-HPV, a red blood cell-based therapeutic cancer vaccine for HPV16+ solid tumors

692 COMMANDER-001: safety data from a phase I/II dose escalation/expansion study of SQZ-eAPC-HPV, a cell-based mRNA therapeutic cancer vaccine for HPV16+ solid tumors

594 SQZ-PBMC-HPV-101: Increased overall survival in a subset of patients with recurrent, locally advanced, or metastatic HPV16+ tumors treated with cell-based vaccine, SQZ-PBMC-HPV

165 Activating antigen carriers generated with microfluidics cell squeezing drive effective anti-tumor responses

Porous PLGA microparticles: AI-700, an intravenously administered ultrasound contrast agent for use in echocardiography

156 RBC-derived, activating antigen carriers (SQZ AACs) prime potent T cell responses and drive tumor regression in vivo

211 SQZ™ eAPCs generated from PBMCs by delivery of multiple mRNAs encoding for antigens, costimulatory proteins, and engineered cytokines

Local anesthetics and mode of delivery : Bupivacaine versus ropivacaine versus levobupivacaine

170 Microfluidics cell squeezing enables potent cellular vaccines in murine models through direct cytosolic loading and direct CD8 T cell priming

Noncompaction Cardiomyopathy: Case Report and Echocardiographic Findings

Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo

Abstract 1524: Peripheral blood mononuclear cells engineered via microfluidic Cell Squeeze® technology to generate APCs that drive mutant-KRas-specific CD8+ T cell responses

Formation of microparticulate protein powder using a supercritical fluid antisolvent

Abstract 1523: Cell Squeeze® delivery of antigen-encoding mRNA enables human PBMCs to drive antigen-specific CD8+ T cell responses for diverse clinical applications

Abstract 1525: Enhancing potency of antigen presenting cells via signal 2/3 mRNA engineering through Cell Squeeze® technology

Abstract 1445: Tumor-specific T cell engineering for enhanced effector function via microfluidic delivery of bioactive molecules

Abstract 3187: Engineering a new generation of cell therapies for solid tumor oncology using the SQZ platform

1743-P: Engineering Erythrocytes with the SQZ Cell Therapy Platform to Enhance Immunotolerance

573. Vector Free Genome Editing of Immune Cells for Cell Therapy

The automated malnutrition assessment

Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid tumors: SQZ-PBMC-HPV-101

Subarachnoid Small-Dose Bupivacaine Versus Lidocaine for Cervical Cerclage

Vector-Free Engineering of Antigen Presenting Cells for Adoptive Immunotherapies for the Treatment of Cancer

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