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X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

The New England journal of medicine, 2015-05, Vol.372 (22), p.2097-2107

2015

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Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (24), p.13680-13688

2020

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La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs

eLife, 2017-04, Vol.6

2017

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The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer

Nucleic acids research, 2016-02, Vol.44 (3), p.1227

2016

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LARP1 on TOP of ribosome production

Wiley interdisciplinary reviews. RNA, 2018-09, Vol.9 (5), p.e1480-n/a

2018

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IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a

Science signaling, 2018-10, Vol.11 (551)

2018

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Capturing the Mechanism Underlying TOP mRNA Binding to LARP1

Structure (London), 2019-12, Vol.27 (12), p.1771-1781.e5

2019

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Genomic study of TEX15 variants: prevalence and allelic heterogeneity in men with spermatogenic failure

Frontiers in genetics, 2023-05, Vol.14, p.1134849-1134849

2023

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Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants

Molecular and Cellular Biology, 2010-10, Vol.30 (20), p.4965-4976

2010

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The ϕ29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition

The EMBO journal, 2006-03, Vol.25 (6), p.1335-1343

2006

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The LARP1 La-Module recognizes both ends of TOP mRNAs

RNA biology, 2021-02, Vol.18 (2), p.248-258

2021

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Controversies around the function of LARP1

RNA biology, 2021-02, Vol.18 (2), p.207-217

2021

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Pathogenic Variants in ZSWIM7 Cause Primary Ovarian Insufficiency

The journal of clinical endocrinology and metabolism, 2022-05, Vol.107 (6), p.e2359-e2364

2022

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mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1

Nucleic acids research, 2021-04, Vol.49 (6), p.3461

2021

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Heterozygous TP63 pathogenic variants in isolated primary ovarian insufficiency

Journal of assisted reproduction and genetics, 2023-09, Vol.40 (9), p.2211-2218

2023

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The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence

Nucleic acids research, 2015-09, Vol.43 (16), p.8077

2015

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A native to amyloidogenic transition regulated by a backbone trigger

Nature structural & molecular biology, 2006-03, Vol.13 (3), p.202-208

2006

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The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis

Nature structural & molecular biology, 2011-12, Vol.18 (12), p.1371

2011

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Reovirus Nonstructural Protein σNS Acts as an RNA Stability Factor Promoting Viral Genome Replication

Journal of virology, 2018-08, Vol.92 (15)

2018

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Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases

The EMBO journal, 2007-07, Vol.26 (14), p.3494-3505

2007

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Effects of Tcte1 knockout on energy chain transportation and spermatogenesis: implications for male infertility

Human reproduction open, 2024, Vol.2024 (2), p.hoae020-hoae020

2024

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SnapShot: Telomeres and Telomerase

Cell, 2012-11, Vol.151 (5), p.1138-1138.e1

2012

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Correction of X-ray intensities from single crystals containing lattice-translocation defects

Acta crystallographica. Section D, Biological crystallography., 2005-01, Vol.61 (1), p.67-74

2005

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A Specific Subdomain in φ29 DNA Polymerase Confers Both Processivity and Strand-Displacement Capacity

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (18), p.6407-6412

2005

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Secondary-Structure Changes Impact LARP1/mRNA Binding: Simulations and Experiments Suggest New Avenues for Anti-Cancer Drug Discovery

Biophysical journal, 2020-02, Vol.118 (3), p.297a-297a

2020

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X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs

The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer

LARP1 on TOP of ribosome production

IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a

Capturing the Mechanism Underlying TOP mRNA Binding to LARP1

Genomic study of TEX15 variants: prevalence and allelic heterogeneity in men with spermatogenic failure

Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants

The ϕ29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition

The LARP1 La-Module recognizes both ends of TOP mRNAs

Controversies around the function of LARP1

Pathogenic Variants in ZSWIM7 Cause Primary Ovarian Insufficiency

mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1

Heterozygous TP63 pathogenic variants in isolated primary ovarian insufficiency

The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence

A native to amyloidogenic transition regulated by a backbone trigger

The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis

Reovirus Nonstructural Protein σNS Acts as an RNA Stability Factor Promoting Viral Genome Replication

Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases

Effects of Tcte1 knockout on energy chain transportation and spermatogenesis: implications for male infertility

SnapShot: Telomeres and Telomerase

Correction of X-ray intensities from single crystals containing lattice-translocation defects

A Specific Subdomain in φ29 DNA Polymerase Confers Both Processivity and Strand-Displacement Capacity

Secondary-Structure Changes Impact LARP1/mRNA Binding: Simulations and Experiments Suggest New Avenues for Anti-Cancer Drug Discovery

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