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The Use of Microdosing in the Development of Small Organic and Protein Therapeutics

Journal of Nuclear Medicine, 2017-08, Vol.58 (8), p.1188-1195

Bergstrom, Mats

2017

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Two binding sites for [ H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

Journal of cerebral blood flow and metabolism, 2010-09, Vol.30 (9), p.1608-1618

2010

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CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis

Arthritis research & therapy, 2023-08, Vol.25 (1), p.158-158, Article 158

2023

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Validation of an automated UPLC-MS/MS method for methylmalonic acid in serum/plasma and its application on clinical samples

Scandinavian journal of clinical and laboratory investigation, 2022-07, Vol.82 (4), p.342-347

2022

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Cerebral Blood Flow Changes After Treatment of Social Phobia with the Neurokinin-1 Antagonist GR205171, Citalopram, or Placebo

Biological psychiatry (1969), 2005-07, Vol.58 (2), p.132-142

2005

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In vivo activity of bupropion at the human dopamine transporter as measured by positron emission tomography

Biological psychiatry (1969), 2003-10, Vol.54 (8), p.800-805

2003

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Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

Biological psychiatry (1969), 2004-05, Vol.55 (10), p.1007-1012

2004

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Detection of Drugs in Oral Fluid Samples Using a Commercially Available Collection Device: Agreement with Urine Testing and Evaluation of A and B Samples Obtained from Employees at Different Workplace Settings with Uncontrolled Sampling Procedures

Journal of analytical toxicology, 2021-01, Vol.44 (9), p.1004-1011

2021

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Cross-species/cross-modality physiologically based pharmacokinetics for biologics: 89Zr-labelled albumin-binding domain antibody GSK3128349 in humans

mAbs, 2020-01, Vol.12 (1), p.1832861

2020

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The biodistribution and clearance of AlbudAb, a novel biopharmaceutical medicine platform, assessed via PET imaging in humans

EJNMMI research, 2019-05, Vol.9 (1), p.45-12, Article 45

2019

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Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI

EJNMMI research, 2019-12, Vol.9 (1), p.1-11, Article 113

2019

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A simple validated multi‐analyte method for detecting drugs in oral fluid by ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS)

Drug testing and analysis, 2018-06, Vol.10 (6), p.1001-1008

2018

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Detection of anabolic androgenic steroids in serum samples

Drug testing and analysis, 2023-06, Vol.15 (6), p.678-688

2023

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In vivo binding of [68 Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours — impact of peptide mass

Nuclear medicine and biology, 2010-04, Vol.37 (3), p.265-275

2010

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Tesofensine, a novel triple monoamine re-uptake inhibitor with anti-obesity effects: Dopamine transporter occupancy as measured by PET

European neuropsychopharmacology, 2014-02, Vol.24 (2), p.251-261

2014

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Phase 0, Including Microdosing Approaches: Applying the Three Rs and Increasing the Efficiency of Human Drug Development

Alternatives to laboratory animals, 2018-12, Vol.46 (6), p.335-346

2018

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Radiopharmaceuticals for oncology drug development: a pharmaceutical industry perspective

Current pharmaceutical design, 2009-03, Vol.15 (9), p.957

2009

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The importance of high specific radioactivity in the performance of Ga-68-labeled peptide

Nuclear medicine and biology, 2008-07, Vol.35 (5), p.529

2008

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In Vitro and In Vivo Primate Evaluation of Carbon-11-Etomidate and Carbon-11-Metomidate as Potential Tracers for PET Imaging of the Adrenal Cortex and Its Tumors

The Journal of nuclear medicine (1978), 1998-06, Vol.39 (6), p.982-989

1998

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[11C]Metomidate Positron Emission Tomography of Adrenocortical Tumors in Correlation with Histopathological Findings

The journal of clinical endocrinology and metabolism, 2006-04, Vol.91 (4), p.1410-1414

2006

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Multimodal imaging distribution assessment of a liposomal antibiotic in an infectious disease model

Journal of controlled release, 2022-12, Vol.352, p.199-210

2022

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Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome

Rheumatology (Oxford, England), 2021-05, Vol.60 (5), p.2396-2408

2021

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Symptom Provocation in Specific Phobia Affects the Substance P Neurokinin-1 Receptor System

Biological psychiatry (1969), 2007-04, Vol.61 (8), p.1002-1006

2007

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Reporting and incidence trends of hydatidiform mole in Sweden 1973-2004

Acta oncologica, 2011-04, Vol.50 (3), p.367-372

2011

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The Use of Microdosing in the Development of Small Organic and Protein Therapeutics

Two binding sites for [ H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis

Validation of an automated UPLC-MS/MS method for methylmalonic acid in serum/plasma and its application on clinical samples

Cerebral Blood Flow Changes After Treatment of Social Phobia with the Neurokinin-1 Antagonist GR205171, Citalopram, or Placebo

In vivo activity of bupropion at the human dopamine transporter as measured by positron emission tomography

Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

Detection of Drugs in Oral Fluid Samples Using a Commercially Available Collection Device: Agreement with Urine Testing and Evaluation of A and B Samples Obtained from Employees at Different Workplace Settings with Uncontrolled Sampling Procedures

Cross-species/cross-modality physiologically based pharmacokinetics for biologics: 89Zr-labelled albumin-binding domain antibody GSK3128349 in humans

The biodistribution and clearance of AlbudAb, a novel biopharmaceutical medicine platform, assessed via PET imaging in humans

Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI

A simple validated multi‐analyte method for detecting drugs in oral fluid by ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS)

Detection of anabolic androgenic steroids in serum samples

Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

In vivo binding of [68 Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours — impact of peptide mass

Tesofensine, a novel triple monoamine re-uptake inhibitor with anti-obesity effects: Dopamine transporter occupancy as measured by PET

Phase 0, Including Microdosing Approaches: Applying the Three Rs and Increasing the Efficiency of Human Drug Development

Radiopharmaceuticals for oncology drug development: a pharmaceutical industry perspective

The importance of high specific radioactivity in the performance of Ga-68-labeled peptide

In Vitro and In Vivo Primate Evaluation of Carbon-11-Etomidate and Carbon-11-Metomidate as Potential Tracers for PET Imaging of the Adrenal Cortex and Its Tumors

[11C]Metomidate Positron Emission Tomography of Adrenocortical Tumors in Correlation with Histopathological Findings

Multimodal imaging distribution assessment of a liposomal antibiotic in an infectious disease model

Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome

Symptom Provocation in Specific Phobia Affects the Substance P Neurokinin-1 Receptor System

Reporting and incidence trends of hydatidiform mole in Sweden 1973-2004

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