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Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor

Journal of internal medicine, 2020-08, Vol.288 (2), p.183-191

2020

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Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF

Oncogene, 2016-03, Vol.35 (10), p.1328-1333

2016

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Podocyte Geranylgeranyl Transferase Type-I Is Essential for Maintenance of the Glomerular Filtration Barrier

Journal of the American Society of Nephrology, 2023-04, Vol.34 (4), p.641-655

2023

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Wild-type KRAS inhibits oncogenic KRAS-induced T-ALL in mice

Leukemia, 2015-05, Vol.29 (5), p.1032-1040

2015

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Targeting Kras g12c -mutant cancer with a mutation-specific inhibitor

Journal of internal medicine, 2020-08, Vol.288 (2), p.183-191

2020

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P1307: TESTING THE IMPORTANCE OF ANTIOXIDANTS ON THE PATHOGENESIS OF B CELL LYMPHOMA

HemaSphere, 2022-06, Vol.6 (Suppl), p.1192-1193

2022

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The long noncoding RNA ADIPINT regulates human adipocyte metabolism via pyruvate carboxylase

Nature communications, 2022-05, Vol.13 (1), p.2958-2958, Article 2958

2022

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A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis

Cell reports (Cambridge), 2023-08, Vol.42 (8), p.112961-112961, Article 112961

2023

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The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway

Scientific reports, 2019-10, Vol.9 (1), p.14667, Article 14667

2019

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Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Aging cell, 2018-12, Vol.17 (6), p.e12835-n/a

2018

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Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A

Oncogenesis (New York, NY), 2014, Vol.3 (9), p.e119-e119

2014

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The Partitioning of Carbon Biomass among the Pico- and Nano-plankton Community in the South Brazilian Bight during a Strong Summer Intrusion of South Atlantic Central Water

Frontiers in Marine Science, 2017-07, Vol.4

2017

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Inactivating GGTase-I reduces disease phenotypes in a mouse model of K-RAS-induced myeloproliferative disease

Leukemia, 2011-01, Vol.25 (1), p.186-189

2011

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Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice

Antioxidants, 2021, Vol.10 (2), p.163

2021

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p37[delta] is a new isoform of PI3K p110[delta] that increases cell proliferation and is overexpressed in tumors

Oncogene, 2012-07, Vol.31 (27), p.3277

2012

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Blocking Protein Farnesyltransferase Improves Nuclear Blebbing in Mouse Fibroblasts with a Targeted Hutchinson-Gilford Progeria Syndrome Mutation

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (29), p.10291-10296

2005

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p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors

Oncogene, 2012-07, Vol.31 (27), p.3277-3286

2012

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On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy

The Journal of biological chemistry, 2004-02, Vol.279 (6), p.4729-4736

2004

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BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

Cell, 2019-07, Vol.178 (2), p.330-345.e22

2019

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Antioxidants can increase melanoma metastasis in mice

Science translational medicine, 2015-10, Vol.7 (308), p.308re8

2015

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Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation

Molecular and Cellular Biology, 2002-01, Vol.22 (1), p.171-181

2002

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The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes

Aging cell, 2020-04, Vol.19 (4), p.e13122-n/a

2020

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Isoprenylcysteine Carboxyl Methyltransferase Deficiency in Mice

The Journal of biological chemistry, 2001-02, Vol.276 (8), p.5841-5845

2001

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Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor

Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF

Podocyte Geranylgeranyl Transferase Type-I Is Essential for Maintenance of the Glomerular Filtration Barrier

Wild-type KRAS inhibits oncogenic KRAS-induced T-ALL in mice

Targeting Kras g12c -mutant cancer with a mutation-specific inhibitor

P1307: TESTING THE IMPORTANCE OF ANTIOXIDANTS ON THE PATHOGENESIS OF B CELL LYMPHOMA

The long noncoding RNA ADIPINT regulates human adipocyte metabolism via pyruvate carboxylase

A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis

The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway

Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A

The Partitioning of Carbon Biomass among the Pico- and Nano-plankton Community in the South Brazilian Bight during a Strong Summer Intrusion of South Atlantic Central Water

Inactivating GGTase-I reduces disease phenotypes in a mouse model of K-RAS-induced myeloproliferative disease

Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice

p37[delta] is a new isoform of PI3K p110[delta] that increases cell proliferation and is overexpressed in tumors

Blocking Protein Farnesyltransferase Improves Nuclear Blebbing in Mouse Fibroblasts with a Targeted Hutchinson-Gilford Progeria Syndrome Mutation

p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors

On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy

BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

Antioxidants can increase melanoma metastasis in mice

Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation

Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes

Isoprenylcysteine Carboxyl Methyltransferase Deficiency in Mice

Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation

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