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Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy

Autophagy, 2016-12, Vol.12 (12), p.2467-2483

2016

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Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease

Cell reports (Cambridge), 2020-11, Vol.33 (8), p.108420-108420, Article 108420

2020

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Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

Nature neuroscience, 2022-06, Vol.25 (6), p.688

2022

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mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy

Cell death & disease, 2019-07, Vol.10 (8), p.563-17, Article 563

2019

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BACE and γ-Secretase Characterization and Their Sorting as Therapeutic Targets to Reduce Amyloidogenesis

Neurochemical research, 2010-02, Vol.35 (2), p.181-210

2010

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Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca2+ efflux and disrupted by PSEN1 loss of function

Science advances, 2022-04, Vol.8 (17), p.eabj5716-eabj5716

2022

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Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders

Neurochemistry international, 2008-01, Vol.52 (1-2), p.184-215

2008

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Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca 2+ efflux and disrupted by PSEN1 loss of function

Science advances, 2022-04, Vol.8 (17), p.eabj5716

2022

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Glucosylceramide synthase decrease in frontal cortex of Alzheimer brain correlates with abnormal increase in endogenous ceramides: Consequences to morphology and viability on enzyme suppression in cultured primary neurons

Brain research, 2008-01, Vol.1191, p.136-147

2008

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Activation of caspase-3 and apoptosis in cerebellar granule cells

Journal of neuroscience research, 1998-05, Vol.52 (3), p.334-341

1998

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Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells

Journal of molecular neuroscience, 2001-12, Vol.17 (3), p.351-360

2001

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APP processing enzymes (secretases) as therapeutic targets: insights from the use of transgenics (Tgs) and transfected cells

Neurochemical research, 2003-07, Vol.28 (7), p.1049-1062

2003

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Gangliosides attenuate ethanol-induced apoptosis in rat cerebellar granule neurons

Neurochemical research, 1999-09, Vol.24 (9), p.1107-1115

1999

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Brain damage results in down-regulation of N-acetylaspartate as a neuronal osmolyte

Neuromolecular medicine, 2003-01, Vol.3 (2), p.95-104

2003

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BACE and [gamma]-Secretase Characterization and Their Sorting as Therapeutic Targets to Reduce Amyloidogenesis

Neurochemical research, 2010-02, Vol.35 (2), p.181

2010

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BACE and g-Secretase Characterization and Their Sorting as Therapeutic Targets to Reduce Amyloidogenesis

Neurochemical research, 2010-02, Vol.35 (2), p.181-210

2010

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Opposite effects of lithium on proximal and distal caspases of immature and mature primary neurons correlate with earlier paradoxical actions on viability

Neurochemical research, 2001-12, Vol.26 (12), p.1311-1320

2001

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Recent advances on neuronal caspases in development and neurodegeneration

Neurochemistry International, 1999-09, Vol.35 (3), p.195-220

1999

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APP processing enzymes (secretases) as therapeutic targets: Insights from the use of transgenics (Tgs) and transfected cells : Application of genetically altered mice models and their significance in neurodegenerative disease

Neurochemical research, 2003, Vol.28 (7), p.1049-1062

2003

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The Semisynthetic Glycosphingolipid LIGA20 Potently Protects Neurons Against Apoptosis

Annals of the New York Academy of Sciences, 1998-06, Vol.845 (1), p.253-262

1998

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The Semisynthetic Glycosphingolipid LIGA 20 Potently Protects Neurons Against Apoptosis

Annals of the New York Academy of Sciences, 1998-06, Vol.845 (1), p.253-262

1998

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Composition of white matter bovine brain coated vesicles: evidence that several components influence β-amyloid peptide to form oligomers and aggregates in vitro

Brain research, 1997-03, Vol.752 (1), p.72-80

1997

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Amyloid (Tace, Bace) and Presenilin Proteases Associated with Alzheimer’s Disease

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases, p.155-178

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Synthetic domains of cystatins linked to enkephalins are novel inhibitors of brain cathepsins L/B

Peptides (New York, N.Y. : 1980), 1990-07, Vol.11 (4), p.679-682

1990

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Met-enkephalin-Arg6-Phe7 metabolism: conversion to Met-enkephalin by brain and kidney dipeptidyl carboxypeptidases

Biochemical and biophysical research communications, 1981-03, Vol.99 (2), p.630-636

1981

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