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Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB2 Receptor

Chembiochem : a European journal of chemical biology, 2024-04, Vol.25 (7), p.e202300785-n/a

2024

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Structural basis of selective cannabinoid CB2 receptor activation

Nature communications, 2023-03, Vol.14 (1), p.1447-1447, Article 1447

2023

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Disruptive selection as a driver of evolutionary branching and caste evolution in social insects

Journal of evolutionary biology, 2016-11, Vol.29 (11), p.2111-2128

2016

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Glycosphingolipids-Nature, Function, and Pharmacological Modulation

Angewandte Chemie (International ed.), 2009-11, Vol.48 (47), p.8848-8869

2009

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Design and Synthesis of Quenched Activity‐based Probes for Diacylglycerol Lipase and α,β‐Hydrolase Domain Containing Protein 6

Chemistry, an Asian journal, 2018-11, Vol.13 (22), p.3491-3500

2018

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Development of Adamantan-1-yl-methoxy-Functionalized 1-Deoxynojirimycin Derivatives as Selective Inhibitors of Glucosylceramide Metabolism in Man

Journal of organic chemistry, 2007-02, Vol.72 (4), p.1088-1097

2007

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Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding

Journal of medicinal chemistry, 2017-01, Vol.60 (1), p.428-440

2017

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The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction

European journal of organic chemistry, 2012-11, Vol.2012 (32), p.6420-6454

2012

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Synthesis of l-altro-1-Deoxynojirimycin, d-allo-1-Deoxynojirimycin, and d-galacto-1-Deoxynojirimycin from a Single Chiral Cyanohydrin

Organic letters, 2010-09, Vol.12 (17), p.3957-3959

2010

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An Efficient Synthesis of the Natural Tetrahydrofuran Pachastrissamine Starting from d-ribo-Phytosphingosine

Journal of organic chemistry, 2006-01, Vol.71 (2), p.836-839

2006

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Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors

Journal of medicinal chemistry, 2014-11, Vol.57 (21), p.9096-9104

2014

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Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors

ChemMedChem, 2015-12, Vol.10 (12), p.2042-2062

2015

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Synthesis of 6‑Hydroxysphingosine and α‑Hydroxy Ceramide Using a Cross-Metathesis Strategy

Journal of organic chemistry, 2015-07, Vol.80 (14), p.7258-7265

2015

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A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals

Scientific reports, 2018-11, Vol.8 (1), p.16421-12, Article 16421

2018

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Placental Characteristics and Reduced Risk of Maternal Breast Cancer

JNCI : Journal of the National Cancer Institute, 2001-08, Vol.93 (15), p.1133-1140

2001

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Two-step activity-based protein profiling of diacylglycerol lipase

Organic & biomolecular chemistry, 2018, Vol.16 (29), p.5250-5253

2018

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The effect of the acute phase of infection on absorption of and exposure to orally administered antibiotics in non-critically ill, hospitalized patients

Journal of antimicrobial chemotherapy, 2023-02, Vol.78 (2), p.389-396

2023

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A randomised controlled trial of aerobic exercise after transient ischaemic attack or minor stroke to prevent cognitive decline: the MoveIT study protocol

BMJ open, 2014-12, Vol.4 (12), p.e007065-e007065

2014

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A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

Journal of the American Chemical Society, 2017-10, Vol.139 (40), p.14192-14197

2017

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Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase

Bioorganic & medicinal chemistry, 2010, Vol.18 (1), p.267-273

2010

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Synthesis and evaluation of homo-bivalent GnRHR ligands

Bioorganic & medicinal chemistry, 2007-07, Vol.15 (14), p.4841-4856

2007

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Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors

Journal of medicinal chemistry, 2024-07

2024

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Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA

Journal of the American Chemical Society, 2023-01, Vol.145 (2), p.1136-1143

2023

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Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish

Journal of lipid research, 2019-11, Vol.60 (11), p.1851-1867

2019

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Preparation of 1-Thio Uronic Acid Lactones and Their Use in Oligosaccharide Synthesis

Organic letters, 2005-05, Vol.7 (10), p.2007-2010

2005

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Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB2 Receptor

Structural basis of selective cannabinoid CB2 receptor activation

Disruptive selection as a driver of evolutionary branching and caste evolution in social insects

Glycosphingolipids-Nature, Function, and Pharmacological Modulation

Design and Synthesis of Quenched Activity‐based Probes for Diacylglycerol Lipase and α,β‐Hydrolase Domain Containing Protein 6

Development of Adamantan-1-yl-methoxy-Functionalized 1-Deoxynojirimycin Derivatives as Selective Inhibitors of Glucosylceramide Metabolism in Man

Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding

The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction

Synthesis of l-altro-1-Deoxynojirimycin, d-allo-1-Deoxynojirimycin, and d-galacto-1-Deoxynojirimycin from a Single Chiral Cyanohydrin

An Efficient Synthesis of the Natural Tetrahydrofuran Pachastrissamine Starting from d-ribo-Phytosphingosine

Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors

Synthesis of 6‑Hydroxysphingosine and α‑Hydroxy Ceramide Using a Cross-Metathesis Strategy

A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals

Placental Characteristics and Reduced Risk of Maternal Breast Cancer

Two-step activity-based protein profiling of diacylglycerol lipase

The effect of the acute phase of infection on absorption of and exposure to orally administered antibiotics in non-critically ill, hospitalized patients

A randomised controlled trial of aerobic exercise after transient ischaemic attack or minor stroke to prevent cognitive decline: the MoveIT study protocol

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase

Synthesis and evaluation of homo-bivalent GnRHR ligands

Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors

Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA

Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish

Preparation of 1-Thio Uronic Acid Lactones and Their Use in Oligosaccharide Synthesis

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