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Camptothecin resistance in cancer: insights into the molecular mechanisms of a DNA-damaging drug

Current medicinal chemistry, 2013-04, Vol.20 (12), p.1541-1565

2013

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Targeting DNA topoisomerase I with non-camptothecin poisons

Current medicinal chemistry, 2012-03, Vol.19 (8), p.1238-1257

2012

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Novel insights into targeting ATP-binding cassette transporters for antitumor therapy

Current medicinal chemistry, 2011-09, Vol.18 (27), p.4237-4249

2011

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Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment

Current medicinal chemistry, 2010-05, Vol.17 (15), p.1500-1508

2010

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Namitecan: a hydrophilic camptothecin with a promising preclinical profile

Current medicinal chemistry, 2012, Vol.19 (21), p.3488-3501

2012

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Mechanisms of cellular resistance to camptothecins

Current medicinal chemistry, 2006-11, Vol.13 (27), p.3291-3305

2006

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ABC transporters as potential targets for modulation of drug resistance

Mini reviews in medicinal chemistry, 2009-08, Vol.9 (9), p.1102-1112

2009

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Global gene expression of fission yeast in response to cisplatin

Cellular and molecular life sciences : CMLS, 2004-09, Vol.61 (17), p.2253-2263

2004

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Gene expression profiles in the cellular response to a multinuclear platinum complexe

Cellular and molecular life sciences : CMLS, 2004-04, Vol.61 (7-8), p.973-981

2004

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Tethering a type IB topoisomerase to a DNA site by enzyme fusion to a heterologous site-selective DNA-binding protein domain

Cancer research (Chicago, Ill.), 1999-08, Vol.59 (15), p.3689-3697

1999

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Small molecules targeting p53 to improve antitumor therapy

Mini reviews in medicinal chemistry, 2008-08, Vol.8 (9), p.856-868

2008

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Development of Resistance to the Atypical Retinoid, ST1926, in the Lung Carcinoma Cell Line H460 Is Associated with Reduced Formation of DNA Strand Breaks and a Defective DNA Damage Response

Neoplasia (New York, N.Y.), 2005-07, Vol.7 (7), p.667-677

2005

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Gene expression profiles in the cellular response to a multinuclear platinum complex

Cellular and molecular life sciences : CMLS, 2004-04, Vol.61 (7-8), p.973

2004

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Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs

Nucleic acids research, 2010-11, Vol.38 (20), p.7089-7099

2010

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Enhanced CPT Sensitivity of Yeast Cells and Selective Relaxation of Gal4 Motif-containing DNA by Novel Gal4–Topoisomerase I Fusion Proteins

Journal of molecular biology, 2004-03, Vol.337 (2), p.295-305

2004

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Gimatecan, a novel camptothecin with a promising preclinical profile

Anti-cancer drugs, 2004-07, Vol.15 (6), p.545-552

2004

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Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards

Oncology reports, 2010-03, Vol.23 (3), p.853-860

2010

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Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells

Biochemical pharmacology, 2004-07, Vol.68 (2), p.283-291

2004

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Anthracycline Chemistry and Biology II: Mode of Action, Clinical Aspects and New Drugs

Krohn, Karsten

2008., 2008

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Interaction Model for Anthracycline Activity against DNA Topoisomerase II

Biochemistry (Easton), 2004-06, Vol.43 (23), p.7503-7513

2004

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Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells

International journal of cancer, 2003-07, Vol.105 (5), p.617-624

2003

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A new synthesis of isoaurones: Cytotoxic activity of compounds related to the alleged structure of isoaurostatin

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4313-4316

2005

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Chemical modification of lysyl residues of Rhodotorula gracilis D-amino acid oxidase

Biochemistry and molecular biology international, 1994-08, Vol.33 (5), p.947-955

1994

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Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

European journal of medicinal chemistry, 2004-06, Vol.39 (6), p.507-513

2004

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Electron Microscopy Analysis of Early Localization of Cisplatin in Ovarian Carcinoma Cells

Ultrastructural pathology, 2002-09, Vol.26 (5), p.331-334

2002

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Camptothecin resistance in cancer: insights into the molecular mechanisms of a DNA-damaging drug

Targeting DNA topoisomerase I with non-camptothecin poisons

Novel insights into targeting ATP-binding cassette transporters for antitumor therapy

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment

Namitecan: a hydrophilic camptothecin with a promising preclinical profile

Mechanisms of cellular resistance to camptothecins

ABC transporters as potential targets for modulation of drug resistance

Global gene expression of fission yeast in response to cisplatin

Gene expression profiles in the cellular response to a multinuclear platinum complexe

Tethering a type IB topoisomerase to a DNA site by enzyme fusion to a heterologous site-selective DNA-binding protein domain

Small molecules targeting p53 to improve antitumor therapy

Development of Resistance to the Atypical Retinoid, ST1926, in the Lung Carcinoma Cell Line H460 Is Associated with Reduced Formation of DNA Strand Breaks and a Defective DNA Damage Response

Gene expression profiles in the cellular response to a multinuclear platinum complex

Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs

Enhanced CPT Sensitivity of Yeast Cells and Selective Relaxation of Gal4 Motif-containing DNA by Novel Gal4–Topoisomerase I Fusion Proteins

Gimatecan, a novel camptothecin with a promising preclinical profile

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards

Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells

Anthracycline Chemistry and Biology II: Mode of Action, Clinical Aspects and New Drugs

Interaction Model for Anthracycline Activity against DNA Topoisomerase II

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells

A new synthesis of isoaurones: Cytotoxic activity of compounds related to the alleged structure of isoaurostatin

Chemical modification of lysyl residues of Rhodotorula gracilis D-amino acid oxidase

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

Electron Microscopy Analysis of Early Localization of Cisplatin in Ovarian Carcinoma Cells

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