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The emerging importance of predictive ADME simulation in drug discovery

Drug Discovery Today, 2002-01, Vol.7 (2), p.109-116

2002

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ADME/PK as part of a rational approach to drug discovery

Drug Discovery Today, 2000-09, Vol.5 (9), p.409-414

2000

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Focus on success: using a probabilistic approach to achieve an optimal balance of compound properties in drug discovery

Expert opinion on drug metabolism & toxicology, 2006-04, Vol.2 (2), p.325-337

2006

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In silico prediction of ADME properties: are we making progress?

Current opinion in drug discovery & development, 2004-01, Vol.7 (1), p.36

2004

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Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102

Toxicology (Amsterdam), 1999-11, Vol.139 (1), p.53-79

1999

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CYP1A1: Friend or Foe?

Drug metabolism reviews, 1993, Vol.25 (4), p.503-517

Beresford, Alan P.

1993

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GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.1032

2007

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Biodiversity of the Bacterial Flora on the Surface of a Smear Cheese

Applied and Environmental Microbiology, 2002-02, Vol.68 (2), p.820-830

2002

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Use of Hydrostatic Pressure for Inactivation of Microbial Contaminants in Cheese

Applied and Environmental Microbiology, 2000-11, Vol.66 (11), p.4890-4896

2000

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Effect of milk pasteurization temperature and in situ whey protein denaturation on the composition, texture and heat-induced functionality of half-fat Cheddar cheese

International dairy journal, 2004-11, Vol.14 (11), p.989-1001

2004

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Archaeogenomic evidence of punctuated genome evolution in Gossypium

Molecular biology and evolution, 2012-08, Vol.29 (8), p.2031-2038

2012

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Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

Journal of medicinal chemistry, 1998-03, Vol.41 (6), p.787-797

1998

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GSK189254, a Novel H 3 Receptor Antagonist That Binds to Histamine H 3 Receptors in Alzheimer's Disease Brain and Improves Cognitive Performance in Preclinical Models

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.1032-1045

2007

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High pressure treatment: applications in cheese manufacture and ripening

Trends in Food Science & Technology, 2001-02, Vol.12 (2), p.51-59

2001

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Effect of milk pasteurisation temperature on age-related changes in lactose metabolism, pH and the growth of non-starter lactic acid bacteria in half-fat Cheddar cheese

Food chemistry, 2007, Vol.100 (1), p.375-382

2007

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Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals

Human molecular genetics, 2013-01, Vol.22 (1), p.184-201

2013

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Effect of high-pressure treatment of 1 day-old full-fat Cheddar cheese on subsequent quality and ripening

Innovative food science & emerging technologies, 2008-10, Vol.9 (4), p.429-440

2008

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Corynebacterium mooreparkense sp. nov. and Corynebacterium casei sp. nov., isolated from the surface of a smear-ripened cheese

International journal of systematic and evolutionary microbiology, 2001-05, Vol.51 (3), p.843-852

2001

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Effects of high-pressure treatment on viability and autolysis of starter bacteria and proteolysis in Cheddar cheese

International dairy journal, 2002, Vol.12 (11), p.915-922

2002

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Microbacterium gubbeenense sp. nov., from the surface of a smear-ripened cheese

International journal of systematic and evolutionary microbiology, 2001-11, Vol.51 (6), p.1969-1976

2001

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High pressure treatment of reduced-fat Mozzarella cheese: Effects on functional and rheological properties

Innovative food science & emerging technologies, 2005-03, Vol.6 (1), p.73-81

2005

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Plasmin activity, β-lactoglobulin denaturation and proteolysis in high pressure treated milk

International dairy journal, 2000, Vol.10 (12), p.835-841

2000

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The emerging importance of predictive ADME simulation in drug discovery

ADME/PK as part of a rational approach to drug discovery

Focus on success: using a probabilistic approach to achieve an optimal balance of compound properties in drug discovery

In silico prediction of ADME properties: are we making progress?

Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102

CYP1A1: Friend or Foe?

GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models

Biodiversity of the Bacterial Flora on the Surface of a Smear Cheese

Use of Hydrostatic Pressure for Inactivation of Microbial Contaminants in Cheese

Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors

TIDEL-II: first-line use of imatinib in CML with early switch to nilotinib for failure to achieve time-dependent molecular targets

Effect of milk pasteurization temperature and in situ whey protein denaturation on the composition, texture and heat-induced functionality of half-fat Cheddar cheese

Archaeogenomic evidence of punctuated genome evolution in Gossypium

Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors

GSK189254, a Novel H 3 Receptor Antagonist That Binds to Histamine H 3 Receptors in Alzheimer's Disease Brain and Improves Cognitive Performance in Preclinical Models

High pressure treatment: applications in cheese manufacture and ripening

Effect of milk pasteurisation temperature on age-related changes in lactose metabolism, pH and the growth of non-starter lactic acid bacteria in half-fat Cheddar cheese

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals

Effect of high-pressure treatment of 1 day-old full-fat Cheddar cheese on subsequent quality and ripening

Corynebacterium mooreparkense sp. nov. and Corynebacterium casei sp. nov., isolated from the surface of a smear-ripened cheese

Effects of high-pressure treatment on viability and autolysis of starter bacteria and proteolysis in Cheddar cheese

Microbacterium gubbeenense sp. nov., from the surface of a smear-ripened cheese

High pressure treatment of reduced-fat Mozzarella cheese: Effects on functional and rheological properties

Plasmin activity, β-lactoglobulin denaturation and proteolysis in high pressure treated milk

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