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Anti-BCMA Immunotoxins: Design, Production, and Preclinical Evaluation

Biomolecules (Basel, Switzerland), 2020-09, Vol.10 (10), p.1387

Bera, Tapan K

2020

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Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4592-4598

2019

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Immunotherapy-based targeting of MSLN⁺ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1-12

2021

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Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

Molecular cancer, 2006-10, Vol.5 (1), p.50-50, Article 50

2006

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Megakaryocytic potentiating factor and mature mesothelin stimulate the growth of a lung cancer cell line in the peritoneal cavity of mice

PloS one, 2014-08, Vol.9 (8), p.e104388

2014

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ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells

PloS one, 2012-05, Vol.7 (5), p.e38130-e38130

2012

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Mesothelin Expression in Human Lung Cancer

Clinical cancer research, 2007-03, Vol.13 (5), p.1571-1575

2007

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Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (18), p.6898-6903

2012

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Domain II of Pseudomonas Exotoxin Is Critical for Efficacy of Bolus Doses in a Xenograft Model of Acute Lymphoblastic Leukemia

Toxins, 2018-05, Vol.10 (5), p.210

2018

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Megakaryocyte Potentiation Factor Cleaved from Mesothelin Precursor Is a Useful Tumor Marker in the Serum of Patients with Mesothelioma

Clinical cancer research, 2006-07, Vol.12 (14), p.4225-4231

2006

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Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE

PloS one, 2013-06, Vol.8 (6), p.e64365-e64365

2013

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A Bispecific Antibody That Targets the Membrane-Proximal Region of Mesothelin and Retains High Anticancer Activity in the Presence of Shed Mesothelin

Molecular cancer therapeutics, 2024-07, Vol.23 (7), p.1021-1030

2024

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Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (15), p.E3501-E3508

2018

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Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin

Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (19), p.e2202439119

2022

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model for obesity and gigantism due to disruption of the Ankrd26 gene

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (1), p.270-275

2008

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Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma

Antibody therapeutics, 2018-06, Vol.1 (1), p.19-25

2018

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Reduced Shedding of Surface Mesothelin Improves Efficacy of Mesothelin-Targeting Recombinant Immunotoxins

Molecular cancer therapeutics, 2016-07, Vol.15 (7), p.1648-1655

2016

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New Monoclonal Antibodies to Mesothelin Useful for Immunohistochemistry, Fluorescence-Activated Cell Sorting, Western Blotting, and ELISA

Clinical cancer research, 2005-08, Vol.11 (16), p.5840-5846

2005

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MRP9, An Unusual Truncated Member of the ABC Transporter Superfamily, is Highly Expressed in Breast Cancer

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (10), p.6997-7002

2002

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POTE paralogs are induced and differentially expressed in many cancers

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.52-56

2006

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Anti-Mesothelin Recombinant Immunotoxin Therapy for Colorectal Cancer

Clinical colorectal cancer, 2019-09, Vol.18 (3), p.192-199.e1

2019

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Site-Specific PEGylation of Anti-Mesothelin Recombinant Immunotoxins Increases Half-life and Antitumor Activity

Molecular cancer therapeutics, 2020-03, Vol.19 (3), p.812-821

2020

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An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies

Leukemia research, 2014-10, Vol.38 (10), p.1224-1229

2014

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NGEP, a Gene Encoding a Membrane Protein Detected Only in Prostate Cancer and Normal Prostate

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.3059-3064

2004

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Evolution and Expression of Chimeric POTE-Actin Genes in the Human Genome

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (47), p.17885-17890

2006

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Anti-BCMA Immunotoxins: Design, Production, and Preclinical Evaluation

Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models

Immunotherapy-based targeting of MSLN⁺ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

Megakaryocytic potentiating factor and mature mesothelin stimulate the growth of a lung cancer cell line in the peritoneal cavity of mice

ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells

Mesothelin Expression in Human Lung Cancer

Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy

Domain II of Pseudomonas Exotoxin Is Critical for Efficacy of Bolus Doses in a Xenograft Model of Acute Lymphoblastic Leukemia

Megakaryocyte Potentiation Factor Cleaved from Mesothelin Precursor Is a Useful Tumor Marker in the Serum of Patients with Mesothelioma

Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE

A Bispecific Antibody That Targets the Membrane-Proximal Region of Mesothelin and Retains High Anticancer Activity in the Presence of Shed Mesothelin

Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity

Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin

model for obesity and gigantism due to disruption of the Ankrd26 gene

Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma

Reduced Shedding of Surface Mesothelin Improves Efficacy of Mesothelin-Targeting Recombinant Immunotoxins

New Monoclonal Antibodies to Mesothelin Useful for Immunohistochemistry, Fluorescence-Activated Cell Sorting, Western Blotting, and ELISA

MRP9, An Unusual Truncated Member of the ABC Transporter Superfamily, is Highly Expressed in Breast Cancer

POTE paralogs are induced and differentially expressed in many cancers

Anti-Mesothelin Recombinant Immunotoxin Therapy for Colorectal Cancer

Site-Specific PEGylation of Anti-Mesothelin Recombinant Immunotoxins Increases Half-life and Antitumor Activity

An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies

NGEP, a Gene Encoding a Membrane Protein Detected Only in Prostate Cancer and Normal Prostate

Evolution and Expression of Chimeric POTE-Actin Genes in the Human Genome

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