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The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

Pharmacology, biochemistry and behavior, 2006-06, Vol.84 (2), p.353-359

2006

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Discovery and optimization of potent and selective functional antagonists of the human adenosine A2B receptor

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5945-5949

2009

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Targeting DYRK1A/B kinases to modulate p21‐cyclin D1‐p27 signalling and induce anti‐tumour activity in a model of human glioblastoma

Journal of cellular and molecular medicine, 2021-11, Vol.25 (22), p.10650-10662

2021

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Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B

Journal of medicinal chemistry, 2021-07, Vol.64 (13), p.8971-8991

2021

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Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors

Journal of medicinal chemistry, 2021-05, Vol.64 (10), p.6745-6764

2021

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Pyrrolo(iso)quinoline derivatives as 5-HT2C receptor agonists

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (3), p.677-680

2006

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Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors

Naunyn-Schmiedeberg's archives of pharmacology, 2004-08, Vol.370 (2)

2004

Volltextzugriff (PDF)

Abstract B163: Identification and preclinical characterisation of VER-250840, a potent, selective Chk1 inhibitor with in vivo oral single-agent antitumor activity

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B163-B163

2018

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Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells

Free radical biology & medicine, 2000-01, Vol.28 (1), p.102-107

2000

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Discovery and functional evaluation of diverse novel human CB1 receptor ligands

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4183-4190

2009

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Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4241-4244

2009

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Fatty acid amide hydrolase inhibitors. 3: Tetra-substituted azetidine ureas with in vivo activity

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.901-906

2012

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Antagonists of the human adenosine A2A receptor. Part 1 Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives

Bioorganic & medicinal chemistry letters, 2008-05, Vol.18 (9), p.2916-2919

2008

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Discovery and functional evaluation of diverse novel human CB sub(1) receptor ligands

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4183-4190

2009

Volltextzugriff (PDF)

Discovery and optimization of potent and selective functional antagonists of the human adenosine A sub(2B) receptor

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5945-5949

2009

Volltextzugriff (PDF)

Discovery and optimization of potent and selective functional antagonists of the human adenosine A 2B receptor

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (20), p.5945-5949

2009

Volltextzugriff (PDF)

Antagonists of the human adenosine A sub(2A) receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives

Bioorganic & medicinal chemistry, 2008-05, Vol.18 (9), p.2916-2919

2008

Volltextzugriff (PDF)

The cannabinoid CB sub(1) receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

Pharmacology, biochemistry and behavior, 2006-06, Vol.84 (2), p.353-359

2006

Volltextzugriff (PDF)

Antagonists of the human adenosine A 2A receptor. Part 1: Discovery and synthesis of thieno[3,2- d]pyrimidine-4-methanone derivatives

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (9), p.2916-2919

2008

Volltextzugriff (PDF)

The cannabinoid CB 1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

Pharmacology, biochemistry and behavior, 2006, Vol.84 (2), p.353-359

2006

Volltextzugriff (PDF)

3,5-Disubstituted-4-hydroxyphenyls Linked to 3-Hydroxy-2-methyl- 4(1H)-pyridinone: Potent Inhibitors of Lipid Peroxidation and Cell Toxicity

Journal of medicinal chemistry, 2000-07, Vol.43 (15), p.2779-2782

2000

Volltextzugriff (PDF)

Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

Naunyn-Schmiedeberg's archives of pharmacology, 2004-08, Vol.370 (2), p.114-123

2004

Volltextzugriff (PDF)

Discovery and functional evaluation of diverse novel human CB(1) receptor ligands

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4183-4190

2009

Volltextzugriff (PDF)

Pyrrolo(iso)quinoline derivatives as 5-HT(2C) receptor agonists

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (3), p.677-680

2006

Volltextzugriff (PDF)

Pyrrolo(iso)quinoline derivatives as 5-HT 2C receptor agonists

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (3), p.677-680

2006

Volltextzugriff (PDF)

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The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

Discovery and optimization of potent and selective functional antagonists of the human adenosine A2B receptor

Targeting DYRK1A/B kinases to modulate p21‐cyclin D1‐p27 signalling and induce anti‐tumour activity in a model of human glioblastoma

Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B

Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors

Pyrrolo(iso)quinoline derivatives as 5-HT2C receptor agonists

Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors

Abstract B163: Identification and preclinical characterisation of VER-250840, a potent, selective Chk1 inhibitor with in vivo oral single-agent antitumor activity

Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells

Discovery and functional evaluation of diverse novel human CB1 receptor ligands

Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas

Fatty acid amide hydrolase inhibitors. 3: Tetra-substituted azetidine ureas with in vivo activity

Antagonists of the human adenosine A2A receptor. Part 1 Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives

Discovery and functional evaluation of diverse novel human CB sub(1) receptor ligands

Discovery and optimization of potent and selective functional antagonists of the human adenosine A sub(2B) receptor

Discovery and optimization of potent and selective functional antagonists of the human adenosine A 2B receptor

Antagonists of the human adenosine A sub(2A) receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives

The cannabinoid CB sub(1) receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

Antagonists of the human adenosine A 2A receptor. Part 1: Discovery and synthesis of thieno[3,2- d]pyrimidine-4-methanone derivatives

The cannabinoid CB 1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

3,5-Disubstituted-4-hydroxyphenyls Linked to 3-Hydroxy-2-methyl- 4(1H)-pyridinone: Potent Inhibitors of Lipid Peroxidation and Cell Toxicity

Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

Discovery and functional evaluation of diverse novel human CB(1) receptor ligands

Pyrrolo(iso)quinoline derivatives as 5-HT(2C) receptor agonists

Pyrrolo(iso)quinoline derivatives as 5-HT 2C receptor agonists

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