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Mechanism-based cancer therapy: resistance to therapy, therapy for resistance

Oncogene, 2015-07, Vol.34 (28), p.3617-3626

2015

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Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

Oncogene, 2015-04, Vol.34 (17), p.2272-2278

2015

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CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

Oncogene, 2015-10, Vol.34 (44), p.5593-5598

2015

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Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R

Oncogenesis (New York, NY), 2013-09, Vol.2 (9), p.e74-e74

2013

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Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma

The Journal of immunology (1950), 2004-11, Vol.173 (9), p.5766-5775

2004

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NF-κB2/p100 induces Bcl-2 expression

Leukemia, 2003-07, Vol.17 (7), p.1349-1356

2003

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Tyrosine phosphatase PTPα contributes to HER2-evoked breast tumor initiation and maintenance

Oncogene, 2014-01, Vol.33 (3), p.398-402

2014

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MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation

Cell death and differentiation, 2014-05, Vol.21 (5), p.811-824

2014

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Nuclear factor-κB, cancer, and apoptosis

Biochemical pharmacology, 2000-10, Vol.60 (8), p.1085-1089

2000

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24: Proffered Paper: JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: A rationale for co-targeting these pathways in metastatic breast cancer

European journal of cancer (1990), 2014-07, Vol.50, p.S7-S7

2014

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Inhibition of the NF-kappa B transcription factor increases Bax expression in cancer cell lines

Oncogene, 2001-05, Vol.20 (22), p.2805-2813

2001

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Stops along the RAS pathway in human genetic disease

Nature medicine, 2006-03, Vol.12 (3), p.283-285

2006

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Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

Cancer research (Chicago, Ill.), 2004-12, Vol.64 (24), p.8816-8820

2004

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Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis

Cancer gene therapy, 2000-01, Vol.7 (1), p.20-26

2000

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NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells

Oncogene, 2003-01, Vol.22 (1), p.90-97

2003

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A role for the scaffolding adapter GAB2 in breast cancer

Nature medicine, 2006-01, Vol.12 (1), p.114-121

2006

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536 Modeling the human breast stem cell and the breast cancer niche

European journal of cancer supplements, 2010, Vol.8 (5), p.137-137

2010

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In vitro and In vivo Activity of the Nuclear Factor-κB Inhibitor Sulfasalazine in Human Glioblastomas

Clinical cancer research, 2004-08, Vol.10 (16), p.5595-5603

2004

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Isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis, induces cell cycle arrest and apoptosis in human colon cancer cells

The Journal of pharmacology and experimental therapeutics, 2003-03, Vol.304 (3), p.1103-1110

2003

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NF-κB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment

Toxicology (Amsterdam), 2000-11, Vol.153 (1), p.27-38

2000

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Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity

Biochemical pharmacology, 2003-05, Vol.65 (10), p.1633-1642

2003

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Roles of nuclear factor-kappaB, p53, and p21/WAF1 in daunomycin-induced cell cycle arrest and apoptosis

The Journal of pharmacology and experimental therapeutics, 2000-12, Vol.295 (3), p.870

2000

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Stable inhibition of nuclear factor κB in cancer cells does not increase sensitivity to cytotoxic drugs

Cancer research (Chicago, Ill.), 1999-02, Vol.59 (4), p.811-815

1999

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Effect of nuclear factor kappaB inhibition on tumor cell sensitivity to natural killer-mediated cytolytic function

European journal of immunology, 2001-02, Vol.31 (2), p.433-439

2001

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Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression

Blood, 2002-03, Vol.99 (6), p.2107-2113

2002

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Mechanism-based cancer therapy: resistance to therapy, therapy for resistance

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R

Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma

NF-κB2/p100 induces Bcl-2 expression

Tyrosine phosphatase PTPα contributes to HER2-evoked breast tumor initiation and maintenance

MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation

Nuclear factor-κB, cancer, and apoptosis

24: Proffered Paper: JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: A rationale for co-targeting these pathways in metastatic breast cancer

Inhibition of the NF-kappa B transcription factor increases Bax expression in cancer cell lines

Stops along the RAS pathway in human genetic disease

Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis

NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells

A role for the scaffolding adapter GAB2 in breast cancer

536 Modeling the human breast stem cell and the breast cancer niche

In vitro and In vivo Activity of the Nuclear Factor-κB Inhibitor Sulfasalazine in Human Glioblastomas

Isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis, induces cell cycle arrest and apoptosis in human colon cancer cells

NF-κB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment

Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity

Roles of nuclear factor-kappaB, p53, and p21/WAF1 in daunomycin-induced cell cycle arrest and apoptosis

Stable inhibition of nuclear factor κB in cancer cells does not increase sensitivity to cytotoxic drugs

Effect of nuclear factor kappaB inhibition on tumor cell sensitivity to natural killer-mediated cytolytic function

Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression

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