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Defective axonal transport: A common pathological mechanism in inherited and acquired peripheral neuropathies

Neurobiology of disease, 2017-09, Vol.105, p.300-320

2017

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HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients

Nature communications, 2017-10, Vol.8 (1), p.861-15, Article 861

2017

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HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease

Brain (London, England : 1878), 2018-03, Vol.141 (3), p.673-687

2018

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Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.4810-4840

2021

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Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome

ACS chemical neuroscience, 2019-03, Vol.10 (3), p.1679-1695

2019

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The role of histone deacetylase 6 (HDAC6) in neurodegeneration

Research and reports in biology, 2014-01, Vol.5, p.1

2014

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ATP13A2 deficiency disrupts lysosomal polyamine export

Nature (London), 2020-02, Vol.578 (7795), p.419-424

2020

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Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot–Marie–Tooth Disease

Neurotherapeutics, 2017-04, Vol.14 (2), p.417-428

2017

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Primary Active Ca2+ Transport Systems in Health and Disease

Cold Spring Harbor perspectives in biology, 2020-02, Vol.12 (2)

2020

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Charcot-Marie-Tooth disease: Emerging mechanisms and therapies

The international journal of biochemistry & cell biology, 2012-08, Vol.44 (8), p.1299-1304

2012

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Primary Active Ca 2+ Transport Systems in Health and Disease

Cold Spring Harbor perspectives in biology, 2020-02, Vol.12 (2), p.a035113

2020

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Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

Chemical communications (Cambridge, England), 2015-06, Vol.51 (48), p.9868-9871

2015

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Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane‐ or Cycloheptane‐Annulated 1,5‐Benzothiazepine Scaffold

Chemistry : a European journal, 2017-01, Vol.23 (1), p.128-136

2017

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Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors

Organic & biomolecular chemistry, 2016-01, Vol.14 (8), p.2537-2549

2016

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Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot–Marie–Tooth Disease

ACS chemical neuroscience, 2016-02, Vol.7 (2), p.240-258

2016

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The Trpa1 Agonist Cinnamaldehyde Acts as a Local Anesthetic Inhibiting Voltage-Gated Sodium Channels in Sensory Neurons

Biophysical journal, 2014-01, Vol.106 (2), p.326a-327a

2014

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Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitorsElectronic supplementary information (ESI) available: Synthetic procedures, spectral data, bioassay results, ligand docking data. See DOI: 10.1039/c5cc03295d

2015-06

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Defective axonal transport: A common pathological mechanism in inherited and acquired peripheral neuropathies

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients

HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease

Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model

Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome

The role of histone deacetylase 6 (HDAC6) in neurodegeneration

ATP13A2 deficiency disrupts lysosomal polyamine export

Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot–Marie–Tooth Disease

Primary Active Ca2+ Transport Systems in Health and Disease

Charcot-Marie-Tooth disease: Emerging mechanisms and therapies

Primary Active Ca 2+ Transport Systems in Health and Disease

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane‐ or Cycloheptane‐Annulated 1,5‐Benzothiazepine Scaffold

Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors

Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot–Marie–Tooth Disease

The Trpa1 Agonist Cinnamaldehyde Acts as a Local Anesthetic Inhibiting Voltage-Gated Sodium Channels in Sensory Neurons

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitorsElectronic supplementary information (ESI) available: Synthetic procedures, spectral data, bioassay results, ligand docking data. See DOI: 10.1039/c5cc03295d

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