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Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization

Nature communications, 2015-01, Vol.6 (1), Article 6163

2015

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Historical Perspective of the G Protein-Coupled Receptor Kinase Family

Cells (Basel, Switzerland), 2021-03, Vol.10 (3), p.555

Benovic, Jeffrey L

2021

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From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins

Biochemical Society transactions, 2016-04, Vol.44 (2), p.555-561

2016

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Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling

The Journal of biological chemistry, 2010-03, Vol.285 (10), p.7805-7817

2010

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Regulation of receptor trafficking by GRKs and arrestins

Annual review of physiology, 2007-01, Vol.69 (1), p.451-482

2007

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Targeting Oncogenic Gα q/11 in Uveal Melanoma

Cancers, 2021-12, Vol.13 (24), p.6195

2021

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Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.E5088-E5097

2013

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G-Protein-Coupled Receptors Signal Victory

Cell, 2012-12, Vol.151 (6), p.1148-1150

Benovic, Jeffrey L.

2012

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Arrestin-2 Interacts with the Ubiquitin-Protein Isopeptide Ligase Atrophin-interacting Protein 4 and Mediates Endosomal Sorting of the Chemokine Receptor CXCR4

The Journal of biological chemistry, 2007-12, Vol.282 (51), p.36971-36979

2007

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How carvedilol does not activate β2-adrenoceptors

Nature communications, 2023-11, Vol.14 (1), p.7866-7866, Article 7866

2023

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Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting

Molecular cell, 2021-01, Vol.81 (2), p.323-339.e11

2021

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G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα

Biochemical journal, 2010-01, Vol.425 (1), p.169-180

2010

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M3 Muscarinic Acetylcholine Receptor-Mediated Signaling Is Regulated by Distinct Mechanisms

Molecular pharmacology, 2008-08, Vol.74 (2), p.338-347

2008

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Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

Molecular cell, 2010-12, Vol.40 (6), p.877-892

2010

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Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines

The FASEB journal, 2018-02, Vol.32 (2), p.862-874

2018

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Biased agonism at β-adrenergic receptors

Cellular signalling, 2021-04, Vol.80, p.109905-109905, Article 109905

2021

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Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking

The Journal of biological chemistry, 2009-10, Vol.284 (43), p.29860-29872

2009

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G protein-coupled receptor kinases: Past, present and future

Cellular signalling, 2018-01, Vol.41, p.17-24

2018

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The E3 Ubiquitin Ligase AIP4 Mediates Ubiquitination and Sorting of the G Protein-Coupled Receptor CXCR4

Developmental cell, 2003-11, Vol.5 (5), p.709-722

2003

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G Protein-Coupled Receptor Kinase 5 Phosphorylation of Hip Regulates Internalization of the Chemokine Receptor CXCR4

Biochemistry (Easton), 2011-08, Vol.50 (32), p.6933-6941

2011

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Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking

Current opinion in cell biology, 2014-04, Vol.27, p.63-71

2014

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Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma

Cancers, 2021-11, Vol.13 (22), p.5749

2021

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The role of receptor kinases and arrestins in G protein-coupled receptor regulation

Annual review of pharmacology and toxicology, 1998-01, Vol.38 (1), p.289-319

1998

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Nonvisual Arrestin Oligomerization and Cellular Localization Are Regulated by Inositol Hexakisphosphate Binding

The Journal of biological chemistry, 2006-04, Vol.281 (14), p.9812-9823

2006

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The ins and outs of G protein-coupled receptor trafficking

Trends in biochemical sciences (Amsterdam. Regular ed.), 2003-07, Vol.28 (7), p.369-376

2003

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Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization

Historical Perspective of the G Protein-Coupled Receptor Kinase Family

From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins

Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling

Regulation of receptor trafficking by GRKs and arrestins

Targeting Oncogenic Gα q/11 in Uveal Melanoma

Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein

G-Protein-Coupled Receptors Signal Victory

Arrestin-2 Interacts with the Ubiquitin-Protein Isopeptide Ligase Atrophin-interacting Protein 4 and Mediates Endosomal Sorting of the Chemokine Receptor CXCR4

How carvedilol does not activate β2-adrenoceptors

Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting

G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα

M3 Muscarinic Acetylcholine Receptor-Mediated Signaling Is Regulated by Distinct Mechanisms

Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines

Biased agonism at β-adrenergic receptors

Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking

G protein-coupled receptor kinases: Past, present and future

The E3 Ubiquitin Ligase AIP4 Mediates Ubiquitination and Sorting of the G Protein-Coupled Receptor CXCR4

G Protein-Coupled Receptor Kinase 5 Phosphorylation of Hip Regulates Internalization of the Chemokine Receptor CXCR4

Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking

Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

Nonvisual Arrestin Oligomerization and Cellular Localization Are Regulated by Inositol Hexakisphosphate Binding

The ins and outs of G protein-coupled receptor trafficking

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