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Animal models of sarcopenia

Aging cell, 2020-10, Vol.19 (10), p.e13223-n/a

2020

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Indoles from commensal bacteria extend healthspan

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (36), p.E7506-E7515

2017

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A family of indoles regulate virulence and Shiga toxin production in pathogenic E. coli

PloS one, 2013-01, Vol.8 (1), p.e54456-e54456

2013

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Titin and Obscurin: Giants Holding Hands and Discovery of a New Ig Domain Subset

Journal of molecular biology, 2015-02, Vol.427 (4), p.707-714

2015

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On-demand optical immobilization of Caenorhabditis elegans for high-resolution imaging and microinjection

Lab on a chip, 2014-09, Vol.14 (18), p.3498-351

2014

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The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells

Nature communications, 2020-10, Vol.11 (1), p.5010-5010, Article 5010

2020

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Muscle contraction phenotypic analysis enabled by optogenetics reveals functional relationships of sarcomere components in Caenorhabditis elegans

Scientific reports, 2016-01, Vol.6 (1), p.19900-19900, Article 19900

2016

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Conformational changes in twitchin kinase in vivo revealed by FRET imaging of freely moving C. elegans

eLife, 2021-09, Vol.10

2021

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Diapause is associated with a change in the polarity of secretion of insulin-like peptides

Nature communications, 2016-02, Vol.7 (1), p.10573-10573, Article 10573

2016

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A Molecular Mechanism for the Requirement of PAT-4 (Integrin-linked Kinase (ILK)) for the Localization of UNC-112 (Kindlin) to Integrin Adhesion Sites

The Journal of biological chemistry, 2012-08, Vol.287 (34), p.28537-28551

2012

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Investigating the correlation of muscle function tests and sarcomere organization in C. elegans

Skeletal muscle, 2021-08, Vol.11 (1), p.20-20, Article 20

2021

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Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

G3 : genes - genomes - genetics, 2022-07, Vol.12 (7)

2022

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Mechanistic and functional diversity in the mechanosensory kinases of the titin-like family

Biochemical Society transactions, 2013-08, Vol.41 (4), p.1066-1071

2013

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Large isoforms of UNC-89 (obscurin) are required for muscle cell architecture and optimal calcium release in Caenorhabditis elegans

PloS one, 2012-07, Vol.7 (7), p.e40182-e40182

2012

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The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle

Molecular biology of the cell, 2024-04, Vol.35 (4), p.ar58-ar58

2024

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Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function

Communications biology, 2024-10, Vol.7 (1), p.1342-16, Article 1342

2024

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Paralysis and killing of Caenorhabditis elegans by enteropathogenic Escherichia coli requires the bacterial tryptophanase gene

Molecular microbiology, 2005-08, Vol.57 (4), p.988-1007

2005

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Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (34), p.13608-13613

2012

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The DH-PH Region of the Giant Protein UNC-89 Activates RHO-1 GTPase in Caenorhabditis elegans Body Wall Muscle

Journal of molecular biology, 2008-11, Vol.383 (4), p.747-752

2008

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FARL-11 (STRIP1/2) is required for sarcomere and sarcoplasmic reticulum organization in C. elegans

Molecular biology of the cell, 2023-08, Vol.34 (9), p.ar86-ar86

2023

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An approach for exploring interaction between two proteins in vivo

Frontiers in physiology, 2014-04, Vol.5, p.162

2014

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The myosin chaperone UNC-45 has an important role in maintaining the structure and function of muscle sarcomeres during adult aging

Molecular biology of the cell, 2024-07, Vol.35 (7), p.mbcE23120488

2024

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Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes

Molecular biology of the cell, 2017-12, Vol.28 (25), p.3621-3633

2017

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Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group–like antigens

The Journal of biological chemistry, 2022-04, Vol.298 (4), p.101704-101704, Article 101704

2022

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Mutations in conserved residues of the myosin chaperone UNC‐45 result in both reduced stability and chaperoning activity

Protein science, 2021-11, Vol.30 (11), p.2221-2232

2021

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Animal models of sarcopenia

Indoles from commensal bacteria extend healthspan

A family of indoles regulate virulence and Shiga toxin production in pathogenic E. coli

Titin and Obscurin: Giants Holding Hands and Discovery of a New Ig Domain Subset

On-demand optical immobilization of Caenorhabditis elegans for high-resolution imaging and microinjection

The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells

Muscle contraction phenotypic analysis enabled by optogenetics reveals functional relationships of sarcomere components in Caenorhabditis elegans

Conformational changes in twitchin kinase in vivo revealed by FRET imaging of freely moving C. elegans

Diapause is associated with a change in the polarity of secretion of insulin-like peptides

A Molecular Mechanism for the Requirement of PAT-4 (Integrin-linked Kinase (ILK)) for the Localization of UNC-112 (Kindlin) to Integrin Adhesion Sites

Investigating the correlation of muscle function tests and sarcomere organization in C. elegans

Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

Mechanistic and functional diversity in the mechanosensory kinases of the titin-like family

Large isoforms of UNC-89 (obscurin) are required for muscle cell architecture and optimal calcium release in Caenorhabditis elegans

The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle

Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function

Paralysis and killing of Caenorhabditis elegans by enteropathogenic Escherichia coli requires the bacterial tryptophanase gene

Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase

The DH-PH Region of the Giant Protein UNC-89 Activates RHO-1 GTPase in Caenorhabditis elegans Body Wall Muscle

FARL-11 (STRIP1/2) is required for sarcomere and sarcoplasmic reticulum organization in C. elegans

An approach for exploring interaction between two proteins in vivo

The myosin chaperone UNC-45 has an important role in maintaining the structure and function of muscle sarcomeres during adult aging

Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes

Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group–like antigens

Mutations in conserved residues of the myosin chaperone UNC‐45 result in both reduced stability and chaperoning activity

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