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Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target

Annals of the New York Academy of Sciences, 2018-12, Vol.1434 (1), p.164-172

2018

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Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1

Journal of virology, 2014-08, Vol.88 (16), p.9429-9441

2014

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Proximity proteomic analysis of the NRF family reveals the Parkinson's disease protein ZNF746/PARIS as a co-complexed repressor of NRF2

Science signaling, 2023-12, Vol.16 (815), p.eadi9018

2023

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Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria

Cell reports (Cambridge), 2023-11, Vol.42 (11), p.113389, Article 113389

2023

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In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

PLoS biology, 2020-12, Vol.18 (12), p.e3000975-e3000975

2020

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The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Molecular biology of the cell, 2021-02, Vol.32 (4), p.314-330

2021

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PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

mBio, 2020-08, Vol.11 (4)

2020

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TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47

Cell reports (Cambridge), 2021-02, Vol.34 (6), p.108743-108743, Article 108743

2021

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Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex

Molecular biology of the cell, 2020-05, Vol.31 (10), p.992-1014

2020

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Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

Journal of cell science, 2020-07, Vol.133 (14)

2020

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Genomic heterogeneity and copy number variant burden are associated with poor recurrence‐free survival and 11q loss in human papillomavirus‐positive squamous cell carcinoma of the oropharynx

Cancer, 2021-08, Vol.127 (15), p.2788-2800

2021

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TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice

Oncogene, 2022-06, Vol.41 (25), p.3423-3432

2022

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PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor

Scientific reports, 2020-09, Vol.10 (1), p.15826-15826, Article 15826

2020

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Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia

Redox biology, 2023-11, Vol.67, p.102901-102901, Article 102901

2023

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Computer‐Aided Design and Synthesis of 1‐{4‐[(3,4‐Dihydroxybenzylidene)amino]phenyl}‐5‐oxopyrrolidine‐3‐carboxylic Acid as an Nrf2 Enhancer

ChemPlusChem (Weinheim, Germany), 2018-05, Vol.83 (5), p.320-333

2018

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Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma

Laryngoscope investigative otolaryngology, 2021-08, Vol.6 (4), p.699-707

2021

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KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle

Journal of virology, 2023-03, Vol.97 (3), p.e0176322-e0176322

2023

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Correction: TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice

Oncogene, 2022-09, Vol.41 (39), p.4485-4485

2022

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Novel inhibitors of leukocyte transendothelial migration

Bioorganic chemistry, 2019-11, Vol.92, p.103250, Article 103250

2019

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Computer‐Aided Design and Synthesis of 1‐{4‐[(3,4‐Dihydroxybenzylidene)amino]phenyl}‐5‐oxopyrrolidine‐3‐carboxylic Acid as an Nrf2 Enhancer

ChemPlusChem (Weinheim, Germany), 2018-05, Vol.83 (5), p.318-318

2018

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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

Cell reports (Cambridge), 2021-07, Vol.36 (2), p.109364-109364, Article 109364

2021

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Abstract 2939: Activation of NRF2 signaling accelerates development of small cell lung cancer in mice

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.2939-2939

2021

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Abstract 5961: NRF2-responsive kinases in esophageal squamous cell carcinoma

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5961-5961

2024

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Genomic Heterogeneity and Copy Number Variant Burden are Associated with Poor Recurrence Free Survival and 11q Loss in HPV+ Squamous Cell Carcinoma of the Oropharynx

Cancer, 2021-04, Vol.127 (15), p.2788-2800

2021

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Correction for Giffin et al., Modulation of Kaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Function by Hypoxia-Upregulated Protein 1

Journal of virology, 2014-11, Vol.88 (21), p.12932-12932

2014

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Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target

Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1

Proximity proteomic analysis of the NRF family reveals the Parkinson's disease protein ZNF746/PARIS as a co-complexed repressor of NRF2

Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex

Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

Genomic heterogeneity and copy number variant burden are associated with poor recurrence‐free survival and 11q loss in human papillomavirus‐positive squamous cell carcinoma of the oropharynx

TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice

PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor

Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia

Computer‐Aided Design and Synthesis of 1‐{4‐[(3,4‐Dihydroxybenzylidene)amino]phenyl}‐5‐oxopyrrolidine‐3‐carboxylic Acid as an Nrf2 Enhancer

Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma

KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle

Correction: TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice

Novel inhibitors of leukocyte transendothelial migration

Computer‐Aided Design and Synthesis of 1‐{4‐[(3,4‐Dihydroxybenzylidene)amino]phenyl}‐5‐oxopyrrolidine‐3‐carboxylic Acid as an Nrf2 Enhancer

Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

Abstract 2939: Activation of NRF2 signaling accelerates development of small cell lung cancer in mice

Abstract 5961: NRF2-responsive kinases in esophageal squamous cell carcinoma

Genomic Heterogeneity and Copy Number Variant Burden are Associated with Poor Recurrence Free Survival and 11q Loss in HPV+ Squamous Cell Carcinoma of the Oropharynx

Correction for Giffin et al., Modulation of Kaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Function by Hypoxia-Upregulated Protein 1

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