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Deconstruction of a Nutlin: Dissecting the Binding Determinants of a Potent Protein–Protein Interaction Inhibitor

ACS medicinal chemistry letters, 2013-07, Vol.4 (7), p.660-665

2013

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Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site

Journal of molecular biology, 2002-02, Vol.316 (2), p.257-264

2002

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Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by HLA-DR Class II MHC Molecules. Design, Structure−Activity Relationships, and X-ray Crystal Structures

Journal of medicinal chemistry, 2000-06, Vol.43 (11), p.2135-2148

2000

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Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1795-1801

2011

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The structure of XIAP BIR2: understanding the selectivity of the BIR domains

Acta crystallographica. Section D, Biological crystallography., 2013-09, Vol.69 (9), p.1717-1725

2013

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Inhibition of Lipopolysaccharide Biosynthesis and Cell Growth following Inactivation of the kdtA Gene in Escherichia coli

The Journal of biological chemistry, 1995-11, Vol.270 (46), p.27646-27652

1995

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Crystal Structures of IL-2-inducible T cell Kinase Complexed with Inhibitors: Insights into Rational Drug Design and Activity Regulation

Chemical biology & drug design, 2010-08, Vol.76 (2), p.154-163

2010

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Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning

The Journal of experimental medicine, 1994-12, Vol.180 (6), p.2353-2358

1994

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HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis

The Journal of experimental medicine, 1996-06, Vol.183 (6), p.2635-2644

1996

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Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase

Biochemical journal, 2003-05, Vol.371 (Pt 3), p.957-964

2003

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Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-manno-octulosonic acid transferase from Escherichia coli

The Journal of biological chemistry, 1992-05, Vol.267 (14), p.9988-9997

1992

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High-Affinity Binding of Short Peptides to Major Histocompatibility Complex Class II Molecules by Anchor Combinations

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (10), p.4456-4460

1994

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Phosphatidylglycerophosphate synthase activity in Saccharomyces cerevisiae

Canadian journal of microbiology, 1983-10, Vol.29 (10), p.1452-1457

1983

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Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules

Nature biotechnology, 1999-06, Vol.17 (6), p.562-567

1999

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A novel 3-deoxy-D-manno-octulosonic acid transferase from Chlamydia trachomatis required for expression of the genus-specific epitope

The Journal of biological chemistry, 1992-09, Vol.267 (26), p.18702-18707

1992

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Fatty acid modulators for the treatment of diabesity

Drug discovery today. Therapeutic strategies, 2007-06, Vol.4 (2), p.129-135

2007

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Phosphatidylinositol 4-kinase from Saccharomyces cerevisiae: Kinetic analysis using Triton X-100/phosphatidylinositol-mixed micelles

The Journal of biological chemistry, 1991-07, Vol.266 (21), p.13859-13865

1991

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Influence of CD26 and integrins on the antigen sensitivity of human memory T cells

Human immunology, 1996-10, Vol.50 (2), p.79-90

1996

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Down‐regulation of class II major histocompatibility complex molecules on antigen‐presenting cells by antibody fragments

European journal of immunology, 1995-12, Vol.25 (12), p.3349-3355

1995

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Phenylalanine ammonia-lyase from illuminated buckwheat hypocotyls and production of monoclonal antibodies

Phytochemistry (Oxford), 1988, Vol.27 (8), p.2485-2489

1988

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[20] Phosphatidylinositol 4-kinase from yeast

Methods in Enzymology, 1992, Vol.209, p.183-189

1992

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Purification and characterization of phosphatidylinositol kinase from Saccharomyces cerevisiae

Belunis, Charles John

1989

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Deconstruction of a Nutlin: Dissecting the Binding Determinants of a Potent Protein–Protein Interaction Inhibitor

Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site

Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by HLA-DR Class II MHC Molecules. Design, Structure−Activity Relationships, and X-ray Crystal Structures

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

The structure of XIAP BIR2: understanding the selectivity of the BIR domains

Inhibition of Lipopolysaccharide Biosynthesis and Cell Growth following Inactivation of the kdtA Gene in Escherichia coli

Crystal Structures of IL-2-inducible T cell Kinase Complexed with Inhibitors: Insights into Rational Drug Design and Activity Regulation

Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning

HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis

Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase

Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-manno-octulosonic acid transferase from Escherichia coli

High-Affinity Binding of Short Peptides to Major Histocompatibility Complex Class II Molecules by Anchor Combinations

Phosphatidylglycerophosphate synthase activity in Saccharomyces cerevisiae

Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules

A novel 3-deoxy-D-manno-octulosonic acid transferase from Chlamydia trachomatis required for expression of the genus-specific epitope

Fatty acid modulators for the treatment of diabesity

Phosphatidylinositol 4-kinase from Saccharomyces cerevisiae: Kinetic analysis using Triton X-100/phosphatidylinositol-mixed micelles

Influence of CD26 and integrins on the antigen sensitivity of human memory T cells

Down‐regulation of class II major histocompatibility complex molecules on antigen‐presenting cells by antibody fragments

Phenylalanine ammonia-lyase from illuminated buckwheat hypocotyls and production of monoclonal antibodies

[20] Phosphatidylinositol 4-kinase from yeast

Purification and characterization of phosphatidylinositol kinase from Saccharomyces cerevisiae

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