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Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients

Scientific reports, 2022-03, Vol.12 (1), p.4374-4374, Article 4374

2022

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ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

iScience, 2020-02, Vol.23 (2), p.100860-100860, Article 100860

2020

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Model-based translation of DNA damage signaling dynamics across cell types

PLoS computational biology, 2022-07, Vol.18 (7), p.e1010264-e1010264

2022

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Tumor-mediated immunosuppression and cytokine spreading affects the relation between EMT and PD-L1 status

Frontiers in immunology, 2023-08, Vol.14, p.1219669-1219669

2023

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Tissue-resident memory CD8⁺ T cells continuously patrol skin epithelia to quickly recognize local antigen

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19739-19744

2012

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DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

Nature communications, 2023-04, Vol.14 (1), p.2184-2184, Article 2184

2023

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Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data

PLoS computational biology, 2020-07, Vol.16 (7), p.e1007972

2020

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Development of a Physiologically Based Pharmacokinetic Model for Nitrofurantoin in Rabbits, Rats, and Humans

Pharmaceutics, 2023-08, Vol.15 (9), p.2199

2023

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Heritable tumor cell division rate heterogeneity induces clonal dominance

PLoS computational biology, 2018-02, Vol.14 (2), p.e1005954-e1005954

2018

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Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

Frontiers in oncology, 2017-08, Vol.7, p.162-162

2017

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Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure

Scientific reports, 2022-05, Vol.12 (1), p.7336-10, Article 7336

2022

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Mathematical Modelling Based on In Vivo Imaging Suggests CD137-Stimulated Cytotoxic T Lymphocytes Exert Superior Tumour Control Due to an Enhanced Antimitotic Effect on Tumour Cells

Cancers, 2021-05, Vol.13 (11), p.2567

2021

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Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors

Frontiers in pharmacology, 2021-08, Vol.12, p.679407-679407

2021

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Random migration and signal integration promote rapid and robust T cell recruitment

PLoS computational biology, 2014-08, Vol.10 (8), p.e1003752-e1003752

2014

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A General Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Target Cells

Biophysical journal, 2014-04, Vol.106 (8), p.1780-1791

2014

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Bidirectional crosstalk between epithelial–mesenchymal plasticity and IFN γ -induced PD-L1 expression promotes tumour progression

Royal Society open science, 2022-11, Vol.9 (11), p.220186-220186

2022

Volltextzugriff (PDF)

Mathematical modeling identifies LAG3 and HAVCR2 as biomarkers of T cell exhaustion in melanoma

iScience, 2023-05, Vol.26 (5), p.106666-106666, Article 106666

2023

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TIL therapy broadens the tumor-reactive CD8+ T cell compartment in melanoma patients

Oncoimmunology, 2012-07, Vol.1 (4), p.409-418

2012

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Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction

Frontiers in cell and developmental biology, 2022-04, Vol.10, p.854721

2022

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Unraveling cellular pathways contributing to drug-induced liver injury by dynamical modeling

Expert opinion on drug metabolism & toxicology, 2017-01, Vol.13 (1), p.5-17

2017

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Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity

The Journal of experimental medicine, 2019-05, Vol.216 (5), p.1038-1049

2019

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A committed tissue-resident memory T cell precursor within the circulating CD8+ effector T cell pool

The Journal of experimental medicine, 2020-10, Vol.217 (10)

2020

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Contact-Dependent Killing by Cytotoxic T Lymphocytes Is Insufficient for EL4 Tumor Regression In Vivo

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13), p.3406-3416

2019

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Chemotactic migration of T cells towards dendritic cells promotes the detection of rare antigens

PLoS computational biology, 2012-11, Vol.8 (11), p.e1002763-e1002763

2012

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B cells within germinal centers migrate preferentially from dark to light zone

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (21), p.8755-8760

2011

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Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients

ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

Model-based translation of DNA damage signaling dynamics across cell types

Tumor-mediated immunosuppression and cytokine spreading affects the relation between EMT and PD-L1 status

Tissue-resident memory CD8⁺ T cells continuously patrol skin epithelia to quickly recognize local antigen

DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data

Development of a Physiologically Based Pharmacokinetic Model for Nitrofurantoin in Rabbits, Rats, and Humans

Heritable tumor cell division rate heterogeneity induces clonal dominance

Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure

Mathematical Modelling Based on In Vivo Imaging Suggests CD137-Stimulated Cytotoxic T Lymphocytes Exert Superior Tumour Control Due to an Enhanced Antimitotic Effect on Tumour Cells

Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors

Random migration and signal integration promote rapid and robust T cell recruitment

A General Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Target Cells

Bidirectional crosstalk between epithelial–mesenchymal plasticity and IFN γ -induced PD-L1 expression promotes tumour progression

Mathematical modeling identifies LAG3 and HAVCR2 as biomarkers of T cell exhaustion in melanoma

TIL therapy broadens the tumor-reactive CD8+ T cell compartment in melanoma patients

Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction

Unraveling cellular pathways contributing to drug-induced liver injury by dynamical modeling

Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity

A committed tissue-resident memory T cell precursor within the circulating CD8+ effector T cell pool

Contact-Dependent Killing by Cytotoxic T Lymphocytes Is Insufficient for EL4 Tumor Regression In Vivo

Chemotactic migration of T cells towards dendritic cells promotes the detection of rare antigens

B cells within germinal centers migrate preferentially from dark to light zone

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