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Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation

PLoS biology, 2014-12, Vol.12 (12), p.e1002011

2014

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Synthesis and Photoisomerization of Substituted Dibenzofulvene Molecular Rotors

Chemistry : a European journal, 2016-08, Vol.22 (32), p.11291-11302

2016

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The signal peptide as a new target for drug design

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (10), p.127115-127115, Article 127115

2020

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Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions

The Science of the total environment, 2024-07, Vol.933, p.173244-173244, Article 173244

2024

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Role of Sec61α2 translocon in insulin biosynthesis

Diabetes (New York, N.Y.), 2024-09

2024

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Synthesis and Evaluation of 4‑Hydroxycoumarin Imines as Inhibitors of Class II Myosins

Journal of medicinal chemistry, 2020-10, Vol.63 (19), p.11131-11148

2020

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Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds

Bioorganic & medicinal chemistry, 2020-12, Vol.28 (24), p.115816-115816, Article 115816

2020

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Supramolecular optical chemosensors for organic analytes

Chemical Society reviews, 2004-11, Vol.33 (9), p.589-598

2004

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Full Visible Spectrum and White Light Emission with a Single, Input-Tunable Organic Fluorophore

Journal of the American Chemical Society, 2020-12, Vol.142 (48), p.20306-20312

2020

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Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II

European journal of medicinal chemistry, 2023-02, Vol.247, p.115008-115008, Article 115008

2023

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A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)

Molecular & cellular proteomics, 2017-02, Vol.16 (2), p.157-167

2017

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Tsuji–Trost Cyclization of Disulfonamides: Synthesis of 12-Membered, 11-Membered, and Pyridine-Fused Macrocyclic Triamines

ACS omega, 2019-01, Vol.4 (1), p.1254-1264

2019

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Controlling the Spatial Orientation of Molecular Actuators: Polarized Photoisomerization of 2-Nitro-9-(2,2,2-triphenylethylidene)fluorene in a Thin Polymer Matrix

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2011-02, Vol.115 (4), p.419-427

2011

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Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds

Journal of medicinal chemistry, 2021-09, Vol.64 (17), p.12865-12876

2021

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Preprotein signature for full susceptibility to the co‐translational translocation inhibitor cyclotriazadisulfonamide

Traffic (Copenhagen, Denmark), 2020-02, Vol.21 (2), p.250-264

2020

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Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility

Journal of Virology, 2009-09, Vol.83 (18), p.9577-9583

2009

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Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2633-2647

2016

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Drugs for Hepatitis C: Unlocking a New Mechanism of Action

ChemMedChem, 2010-10, Vol.5 (10), p.1663-1665

Bell, Thomas W.

2010

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Proton‐Gated Photoisomerization of Amino‐Substituted Dibenzofulvene Rotors

Chemphyschem, 2017-01, Vol.18 (1), p.59-63

2017

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The Anti-HIV Potency of Cyclotriazadisulfonamide Analogs Is Directly Correlated with Their Ability to Down-Modulate the CD4 Receptor

Molecular pharmacology, 2003-01, Vol.63 (1), p.203-210

2003

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Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4

Organic & biomolecular chemistry, 2015-01, Vol.13 (42), p.10517-10526

2015

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Circular Dichroism Readout of Sugar Recognition in the Cleft of a Fused-Pyridine Receptor

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (8), p.4972-4976

2002

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Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonization

AIDS research and therapy, 2010-06, Vol.7 (1), p.16-16, Article 16

2010

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Cadmium- and zinc-alloyed Cu–In–S nanocrystals and their optical properties

Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2013-11, Vol.15 (11), p.1-10, Article 2056

2013

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Unsymmetrical Cyclotriazadisulfonamide (CADA) Compounds as Human CD4 Receptor Down-Modulating Agents

Journal of medicinal chemistry, 2011-08, Vol.54 (16), p.5712-5721

2011

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Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation

Synthesis and Photoisomerization of Substituted Dibenzofulvene Molecular Rotors

The signal peptide as a new target for drug design

Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions

Role of Sec61α2 translocon in insulin biosynthesis

Synthesis and Evaluation of 4‑Hydroxycoumarin Imines as Inhibitors of Class II Myosins

Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds

Supramolecular optical chemosensors for organic analytes

Full Visible Spectrum and White Light Emission with a Single, Input-Tunable Organic Fluorophore

Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II

A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)

Tsuji–Trost Cyclization of Disulfonamides: Synthesis of 12-Membered, 11-Membered, and Pyridine-Fused Macrocyclic Triamines

Controlling the Spatial Orientation of Molecular Actuators: Polarized Photoisomerization of 2-Nitro-9-(2,2,2-triphenylethylidene)fluorene in a Thin Polymer Matrix

Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds

Preprotein signature for full susceptibility to the co‐translational translocation inhibitor cyclotriazadisulfonamide

Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility

Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies

Drugs for Hepatitis C: Unlocking a New Mechanism of Action

Proton‐Gated Photoisomerization of Amino‐Substituted Dibenzofulvene Rotors

The Anti-HIV Potency of Cyclotriazadisulfonamide Analogs Is Directly Correlated with Their Ability to Down-Modulate the CD4 Receptor

Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4

Circular Dichroism Readout of Sugar Recognition in the Cleft of a Fused-Pyridine Receptor

Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonization

Cadmium- and zinc-alloyed Cu–In–S nanocrystals and their optical properties

Unsymmetrical Cyclotriazadisulfonamide (CADA) Compounds as Human CD4 Receptor Down-Modulating Agents

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