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The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

Cell host & microbe, 2015-06, Vol.17 (6), p.811-819

2015

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A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

Nature (London), 2019-05, Vol.569 (7758), p.718-722

2019

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LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis

eLife, 2020-02, Vol.9

2020

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Exploring the "Multiple-Hit Hypothesis" of Neurodegenerative Disease: Bacterial Infection Comes Up to Bat

Frontiers in cellular and infection microbiology, 2019-05, Vol.9, p.138-138

2019

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An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses

Molecular cell, 2018-08, Vol.71 (4), p.637-648.e5

2018

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The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009888-e1009888

2021

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Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

PLoS pathogens, 2023-06, Vol.19 (6), p.e1011088-e1011088

2023

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Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum

Bioorganic & medicinal chemistry, 2009-02, Vol.17 (4), p.1527-1533

2009

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Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

Cell, 2022-08, Vol.185 (17), p.3214-3231.e23

2022

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Expression of a malarial Hsp70 improves defects in chaperone-dependent activities in ssa1 mutant yeast

PloS one, 2011-05, Vol.6 (5), p.e20047

2011

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Bug in the code: TB blocks DNA repair

Cell host & microbe, 2023-11, Vol.31 (11), p.1769-1771

2023

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Interactions between fungal hyaluronic acid and host CD44 promote internalization by recruiting host autophagy proteins to forming phagosomes

iScience, 2021-03, Vol.24 (3), p.102192-102192, Article 102192

2021

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TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection

The Journal of immunology (1950), 2020-07, Vol.205 (1), p.153-167

2020

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For Better or Worse: Cytosolic DNA Sensing during Intracellular Bacterial Infection Induces Potent Innate Immune Responses

Journal of molecular biology, 2016-08, Vol.428 (17), p.3372-3386

2016

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Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice

Science advances, 2021-05, Vol.7 (22)

2021

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The BiP Molecular Chaperone Plays Multiple Roles during the Biogenesis of TorsinA, an AAA+ ATPase Associated with the Neurological Disease Early-onset Torsion Dystonia

The Journal of biological chemistry, 2014-05, Vol.289 (18), p.12727-12747

2014

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Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection

Cell systems, 2018-09, Vol.7 (3), p.323-338.e6

2018

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Gasdermin D promotes hyperinflammation by triggering necroptosis in the presence of mitochondrial stress

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.52-52.06

2022

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LRRK2 is required for macrophage homeostasis and the control of type I IFN

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.169-169.16

2018

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Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control italic toggle="yes">Mycobacterium tuberculosis /italic> Infection in Macrophages

mBio, 2021-08, Vol.12 (4)

2021

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An Mtb-Human Protein-Protein Interaction Map Identifies a Switch Between Host Anti-Viral and Anti-Bacterial Responses

Molecular cell, 2018-08, Vol.71 (4), p.637-648.e5

2018

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Mycobacterial PE/PPE proteins function as “personal protective equipment” against host defenses

Frontiers in Tuberculosis, 2024-09, Vol.2

2024

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Cytosolic detection of the vacuolar pathogen, Mycobacterium tuberculosis

Bell, Samantha L

2015

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Pathways linking biodiversity to human health: A conceptual framework

Environment international, 2021-05, Vol.150, p.106420, Article 106420

2021

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Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2020-02, Vol.323 (5), p.423

2020

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The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis

Exploring the "Multiple-Hit Hypothesis" of Neurodegenerative Disease: Bacterial Infection Comes Up to Bat

An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses

The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

Expression of a malarial Hsp70 improves defects in chaperone-dependent activities in ssa1 mutant yeast

Bug in the code: TB blocks DNA repair

Interactions between fungal hyaluronic acid and host CD44 promote internalization by recruiting host autophagy proteins to forming phagosomes

TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection

For Better or Worse: Cytosolic DNA Sensing during Intracellular Bacterial Infection Induces Potent Innate Immune Responses

Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice

The BiP Molecular Chaperone Plays Multiple Roles during the Biogenesis of TorsinA, an AAA+ ATPase Associated with the Neurological Disease Early-onset Torsion Dystonia

Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection

Gasdermin D promotes hyperinflammation by triggering necroptosis in the presence of mitochondrial stress

LRRK2 is required for macrophage homeostasis and the control of type I IFN

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control italic toggle="yes">Mycobacterium tuberculosis /italic> Infection in Macrophages

An Mtb-Human Protein-Protein Interaction Map Identifies a Switch Between Host Anti-Viral and Anti-Bacterial Responses

Mycobacterial PE/PPE proteins function as “personal protective equipment” against host defenses

Cytosolic detection of the vacuolar pathogen, Mycobacterium tuberculosis

Pathways linking biodiversity to human health: A conceptual framework

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial

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