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Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors

Annals of oncology, 2019-02, Vol.30 (2), p.219-235

2019

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Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

Journal of inorganic biochemistry, 2012-01, Vol.106 (1), p.90-99

2012

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DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update

Annals of oncology, 2017-12, Vol.28 (12), p.2915-2922

2017

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A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours

British journal of cancer, 2012-05, Vol.106 (10), p.1598-1604

2012

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Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

Journal of antimicrobial chemotherapy, 2012-11, Vol.67 (11), p.2576-2597

2012

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Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option

British journal of cancer, 2014-10, Vol.111 (9), p.1726-1733

2014

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Optimizing anticancer drug treatment in pregnant cancer patients: pharmacokinetic analysis of gestation-induced changes for doxorubicin, epirubicin, docetaxel and paclitaxel

Annals of oncology, 2014-10, Vol.25 (10), p.2059-2065

2014

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Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique

Cancer treatment reviews, 2016-11, Vol.50, p.247-263

2016

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Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study

Annals of oncology, 2022-10, Vol.33 (10), p.1071-1082

2022

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Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918

Journal of clinical oncology, 2002-07, Vol.20 (13), p.2943-2950

2002

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HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53

British journal of cancer, 2015-04, Vol.112 (8), p.1358-1366

2015

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Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

Journal of pharmaceutical and biomedical analysis, 2017-02, Vol.135, p.160-166

2017

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Exposure–response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients

Cancer chemotherapy and pharmacology, 2023-06, Vol.91 (6), p.447-456

2023

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Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-07, Vol.1090, p.14-21

2018

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Pharmacokinetically guided sunitinib dosing: a feasibility study in patients with advanced solid tumours

British journal of cancer, 2014-05, Vol.110 (10), p.2441-2449

2014

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Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019-01, Vol.1104, p.234-239

2019

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Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-02, Vol.1138, p.121925-121925, Article 121925

2020

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Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (2), p.205-212

2008

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Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2020-01, Vol.177, p.112871, Article 112871

2020

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Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

British journal of pharmacology, 2010-07, Vol.160 (5), p.1224-1233

2010

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Development and validation of a liquid chromatography–tandem mass spectrometry analytical method for the therapeutic drug monitoring of eight novel anticancer drugs

Biomedical chromatography, 2018-04, Vol.32 (4), p.n/a

2018

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Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)

International journal of pharmaceutics, 2011-11, Vol.420 (2), p.244-250

2011

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Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL)

Pharmazie, 2023-08, Vol.78 (8), p.107-112

2023

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Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation

British journal of cancer, 2014-05, Vol.110 (11), p.2669-2676

2014

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The development and validation of a high performance liquid chromatography method to determine the radiochemical purity of [177Lu]Lu-HA-DOTA-TATE in pharmaceutical preparations

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-05, Vol.1171, p.122605-122605, Article 122605

2021

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Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors

Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update

A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours

Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option

Optimizing anticancer drug treatment in pregnant cancer patients: pharmacokinetic analysis of gestation-induced changes for doxorubicin, epirubicin, docetaxel and paclitaxel

Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique

Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study

Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918

HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53

Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

Exposure–response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry

Pharmacokinetically guided sunitinib dosing: a feasibility study in patients with advanced solid tumours

Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling

Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors

Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass spectrometry

Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

Development and validation of a liquid chromatography–tandem mass spectrometry analytical method for the therapeutic drug monitoring of eight novel anticancer drugs

Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)

Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL)

Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation

The development and validation of a high performance liquid chromatography method to determine the radiochemical purity of [177Lu]Lu-HA-DOTA-TATE in pharmaceutical preparations

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