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Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides

Nucleic acids research, 2016-01, Vol.44 (2), p.863

2016

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Progress towards in vivo use of siRNAs

Molecular therapy, 2006-04, Vol.13 (4), p.644-670

Behlke, Mark A

2006

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Identification of preexisting adaptive immunity to Cas9 proteins in humans

Nature medicine, 2019-02, Vol.25 (2), p.249-254

2019

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A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells

Nature medicine, 2018-08, Vol.24 (8), p.1216-1224

2018

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Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

Developmental cell, 2019-12, Vol.51 (5), p.645-657.e4

2019

Volltextzugriff (PDF)

Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins

Genome Biology, 2017-05, Vol.18 (1), p.92-15, Article 92

2017

Volltextzugriff (PDF)

CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy

Science advances, 2020-11, Vol.6 (47)

2020

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Progress Toward In Vivo Use of siRNAs-II

Molecular therapy, 2012-03, Vol.20 (3), p.483-512

2012

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A Direct Comparison of Anti-microRNA Oligonucleotide Potency

Pharmaceutical research, 2010-09, Vol.27 (9), p.1788-1799

2010

Volltextzugriff (PDF)

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

Cell metabolism, 2011-07, Vol.14 (1), p.33-44

2011

Volltextzugriff (PDF)

A modular platform for targeted RNAi therapeutics

Nature nanotechnology, 2018-03, Vol.13 (3), p.214-219

2018

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Engineered transfer RNAs for suppression of premature termination codons

Nature communications, 2019-02, Vol.10 (1), p.822-822, Article 822

2019

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Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection

PloS one, 2012-09, Vol.7 (9), p.e43836-e43836

2012

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Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

Nucleic acids research, 2011-07, Vol.39 (13), p.5692

2011

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Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target

Journal of controlled release, 2019-11, Vol.313, p.33-41

2019

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Predicting Stability of DNA Duplexes in Solutions Containing Magnesium and Monovalent Cations

Biochemistry (Easton), 2008-05, Vol.47 (19), p.5336-5353

2008

Volltextzugriff (PDF)

RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers

BMC biotechnology, 2011-08, Vol.11 (1), p.80-80, Article 80

2011

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

Nature biotechnology, 2005-02, Vol.23 (2), p.222-226

2005

Volltextzugriff (PDF)

Chemical Modifications in RNA Interference and CRISPR/Cas Genome Editing Reagents

Methods in molecular biology (Clifton, N.J.), 2020-01, Vol.2115, p.23

2020

Volltextzugriff (PDF)

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes

Methods (San Diego, Calif.), 2017-05, Vol.121-122, p.16-28

2017

Volltextzugriff (PDF)

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish

PloS one, 2015-10, Vol.10 (10), p.e0139504

2015

Volltextzugriff (PDF)

SNP detection in mRNA in living cells using allele specific FRET probes

PloS one, 2013-09, Vol.8 (9), p.e72389-e72389

2013

Volltextzugriff (PDF)

In vivo SELEX for Identification of Brain-penetrating Aptamers

Molecular therapy. Nucleic acids, 2013-01, Vol.2 (1), p.e67-e67, Article e67

2013

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Single-molecule detection and tracking of RNA transcripts in living cells using phosphorothioate-optimized 2′- O -methyl RNA molecular beacons

Biomaterials, 2016-09, Vol.100, p.172-183

2016

Volltextzugriff (PDF)

Rational Design of Small Molecules to Enhance Genome Editing Efficiency by Selectively Targeting Distinct Functional States of CRISPR-Cas12a

Bioconjugate chemistry, 2020-03, Vol.31 (3), p.542-546

2020

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Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides

Progress towards in vivo use of siRNAs

Identification of preexisting adaptive immunity to Cas9 proteins in humans

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells

Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins

CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy

Progress Toward In Vivo Use of siRNAs-II

A Direct Comparison of Anti-microRNA Oligonucleotide Potency

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

A modular platform for targeted RNAi therapeutics

Engineered transfer RNAs for suppression of premature termination codons

Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target

Predicting Stability of DNA Duplexes in Solutions Containing Magnesium and Monovalent Cations

RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

Chemical Modifications in RNA Interference and CRISPR/Cas Genome Editing Reagents

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish

SNP detection in mRNA in living cells using allele specific FRET probes

In vivo SELEX for Identification of Brain-penetrating Aptamers

Single-molecule detection and tracking of RNA transcripts in living cells using phosphorothioate-optimized 2′- O -methyl RNA molecular beacons

Rational Design of Small Molecules to Enhance Genome Editing Efficiency by Selectively Targeting Distinct Functional States of CRISPR-Cas12a

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