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Dibenzothiophene Catabolism Proceeds via a Flavin-N5-oxide Intermediate

Journal of the American Chemical Society, 2016-05, Vol.138 (20), p.6424-6426

2016

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RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide

Biochemistry (Easton), 2017-07, Vol.56 (29), p.3708-3709

2017

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Introduction to metabolomics and its applications in ophthalmology

Eye (London), 2016-06, Vol.30 (6), p.773-783

2016

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The structural and biochemical foundations of thiamin biosynthesis

Annual review of biochemistry, 2009-01, Vol.78 (1), p.569-603

2009

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Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme

Journal of the American Chemical Society, 2013-10, Vol.135 (41), p.15318-15321

2013

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Tryptophan Lyase (NosL): A Cornucopia of 5′-Deoxyadenosyl Radical Mediated Transformations

Journal of the American Chemical Society, 2016-12, Vol.138 (50), p.16184-16187

2016

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Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme

Journal of the American Chemical Society, 2017-02, Vol.139 (5), p.1742-1745

2017

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Mechanistic Studies on Tryptophan Lyase (NosL): Identification of Cyanide as a Reaction Product

Journal of the American Chemical Society, 2018-01, Vol.140 (2), p.542-545

2018

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Anaerobic biosynthesis of the lower ligand of vitamin B12

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.10792-10797

2015

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Menaquinone Biosynthesis: New Strategies to Trap Radical Intermediates in the MqnE-Catalyzed Reaction

Biochemistry (Easton), 2021-06, Vol.60 (21), p.1642-1646

2021

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Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase

Nature (London), 2011-10, Vol.478 (7370), p.542-546

2011

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Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

Analyst (London), 2009-01, Vol.134 (7), p.1322-1332

2009

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Aminofutalosine Synthase (MqnE): A New Catalytic Motif in Radical SAM Enzymology

Methods in enzymology, 2018, Vol.606, p.179-198

2018

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Identification of the functional pathways altered by placental cell exposure to high glucose: lessons from the transcript and metabolite interactome

Scientific reports, 2018-03, Vol.8 (1), p.5270-11, Article 5270

2018

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Pyridoxal phosphate: Biosynthesis and catabolism

Biochimica et biophysica acta, 2011-11, Vol.1814 (11), p.1585-1596

2011

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Mechanistic Studies on CysS - A Vitamin B 12 -Dependent Radical SAM Methyltransferase Involved in the Biosynthesis of the tert -Butyl Group of Cystobactamid

Journal of the American Chemical Society, 2020-06, Vol.142 (22), p.9944-9954

2020

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Phosphomethylpyrimidine Synthase (ThiC): Trapping of Five Intermediates Provides Mechanistic Insights on a Complex Radical Cascade Reaction in Thiamin Biosynthesis

ACS central science, 2024-05, Vol.10 (5), p.988-1000

2024

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Alkylcysteine Sulfoxide C–S Monooxygenase Uses a Flavin-Dependent Pummerer Rearrangement

Journal of the American Chemical Society, 2023-06, Vol.145 (22), p.11933-11938

2023

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Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo• Radical in a Radical S‑Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate

ACS central science, 2019-11, Vol.5 (11), p.1777-1785

2019

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Thiamin biosynthesis: still yielding fascinating biological chemistry

Biochemical Society transactions, 2012-06, Vol.40 (3), p.555-560

2012

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High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana

Journal of structural biology, 2013-12, Vol.184 (3), p.438-444

2013

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Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily

Nature chemical biology, 2008-12, Vol.4 (12), p.758-765

2008

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The Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A Antimetabolite

The Journal of biological chemistry, 2002-12, Vol.277 (50), p.48205-48209

2002

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Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase

Nature communications, 2015-03, Vol.6 (1), p.6480-6480, Article 6480

2015

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Top Down Characterization of Larger Proteins (45 kDa) by Electron Capture Dissociation Mass Spectrometry

Journal of the American Chemical Society, 2002-01, Vol.124 (4), p.672-678

2002

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Dibenzothiophene Catabolism Proceeds via a Flavin-N5-oxide Intermediate

RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide

Introduction to metabolomics and its applications in ophthalmology

The structural and biochemical foundations of thiamin biosynthesis

Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme

Tryptophan Lyase (NosL): A Cornucopia of 5′-Deoxyadenosyl Radical Mediated Transformations

Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme

Mechanistic Studies on Tryptophan Lyase (NosL): Identification of Cyanide as a Reaction Product

Anaerobic biosynthesis of the lower ligand of vitamin B12

Menaquinone Biosynthesis: New Strategies to Trap Radical Intermediates in the MqnE-Catalyzed Reaction

Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase

Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

Aminofutalosine Synthase (MqnE): A New Catalytic Motif in Radical SAM Enzymology

Identification of the functional pathways altered by placental cell exposure to high glucose: lessons from the transcript and metabolite interactome

Pyridoxal phosphate: Biosynthesis and catabolism

Mechanistic Studies on CysS - A Vitamin B 12 -Dependent Radical SAM Methyltransferase Involved in the Biosynthesis of the tert -Butyl Group of Cystobactamid

Phosphomethylpyrimidine Synthase (ThiC): Trapping of Five Intermediates Provides Mechanistic Insights on a Complex Radical Cascade Reaction in Thiamin Biosynthesis

Alkylcysteine Sulfoxide C–S Monooxygenase Uses a Flavin-Dependent Pummerer Rearrangement

Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo• Radical in a Radical S‑Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate

Thiamin biosynthesis: still yielding fascinating biological chemistry

High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily

The Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A Antimetabolite

Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase

Top Down Characterization of Larger Proteins (45 kDa) by Electron Capture Dissociation Mass Spectrometry

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