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ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Nature (London), 2022-06, Vol.606 (7914), p.594-602

2022

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Phase I/Ib Study of Pembrolizumab Plus Vorinostat in Advanced/Metastatic Non-Small Cell Lung Cancer

Clinical cancer research, 2019-11, Vol.25 (22), p.6623-6632

2019

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Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm

PLoS pathogens, 2011-10, Vol.7 (10), p.e1002165-e1002165

2011

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Proteogenomic landscape of squamous cell lung cancer

Nature communications, 2019-08, Vol.10 (1), p.3578-17, Article 3578

2019

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Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

Nature communications, 2019-08, Vol.10 (1), p.3716-15, Article 3716

2019

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Utilization of target lesion heterogeneity for treatment efficacy assessment in late stage lung cancer

PloS one, 2021-07, Vol.16 (7), p.e0252041-e0252041

2021

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Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (30), p.12414-12419

2013

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Distinct Roles for the NF-κB RelA Subunit during Antiviral Innate Immune Responses

Journal of Virology, 2011-03, Vol.85 (6), p.2599-2610

2011

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Interferons Direct an Effective Innate Response to Legionella pneumophila Infection

The Journal of biological chemistry, 2009-10, Vol.284 (44), p.30058-30066

2009

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Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma

Cancer research (Chicago, Ill.), 2009-12, Vol.69 (24), p.9367-9375

2009

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Activation of Dendritic Cells via Inhibition of Jak2/STAT3 Signaling

Journal of Immunology, 2005-10, Vol.175 (7), p.4338-4346

2005

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HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma

Clinical cancer research, 2016-08, Vol.22 (16), p.4119-4132

2016

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NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

Nature cell biology, 2011-10, Vol.13 (10), p.1272-1279

2011

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Histone Deacetylase Inhibitors Directly Modulate T Cell Gene Expression and Signaling and Promote Development of Effector-Exhausted T Cells in Murine Tumors

The Journal of immunology (1950), 2024-02, Vol.212 (4), p.737-747

2024

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TIMEx: tumor-immune microenvironment deconvolution web-portal for bulk transcriptomics using pan-cancer scRNA-seq signatures

Bioinformatics (Oxford, England), 2021-10, Vol.37 (20), p.3681-3683

2021

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The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis

The Journal of experimental medicine, 2011-10, Vol.208 (11), p.2321-2333

2011

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PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

Molecular and Cellular Biology, 2003-10, Vol.23 (20), p.7122-7133

2003

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Mechanism of All-Trans Retinoic Acid Effect on Tumor-Associated Myeloid-Derived Suppressor Cells

Cancer research (Chicago, Ill.), 2007-11, Vol.67 (22), p.11021-11028

2007

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Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

Trends in immunology, 2002-11, Vol.23 (11), p.509-512

Beg, Amer A

2002

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Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non-Small Cell Lung Cancer

Clinical cancer research, 2022-06, Vol.28 (11), p.2313-2320

2022

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An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2

Biochemical and biophysical research communications, 2002-11, Vol.299 (2), p.216-221

2002

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NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication

The Journal of immunology (1950), 2010-08, Vol.185 (3), p.1720-1729

2010

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Bid-Independent Mitochondrial Activation in Tumor Necrosis Factor Alpha-Induced Apoptosis and Liver Injury

Molecular and Cellular Biology, 2007-01, Vol.27 (2), p.541-553

2007

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Rapid Autopsy to Define Dendritic Cell Spatial Distribution and T Cell Association in Lung Adenocarcinoma

The Journal of immunology (1950), 2024-10, Vol.213 (7), p.1033

2024

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Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance

The Journal of clinical investigation, 2013-06, Vol.123 (6), p.2509-2522

2013

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ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Phase I/Ib Study of Pembrolizumab Plus Vorinostat in Advanced/Metastatic Non-Small Cell Lung Cancer

Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm

Proteogenomic landscape of squamous cell lung cancer

Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

Utilization of target lesion heterogeneity for treatment efficacy assessment in late stage lung cancer

Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells

Distinct Roles for the NF-κB RelA Subunit during Antiviral Innate Immune Responses

Interferons Direct an Effective Innate Response to Legionella pneumophila Infection

Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma

Activation of Dendritic Cells via Inhibition of Jak2/STAT3 Signaling

HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma

NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

Histone Deacetylase Inhibitors Directly Modulate T Cell Gene Expression and Signaling and Promote Development of Effector-Exhausted T Cells in Murine Tumors

TIMEx: tumor-immune microenvironment deconvolution web-portal for bulk transcriptomics using pan-cancer scRNA-seq signatures

The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis

PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

Mechanism of All-Trans Retinoic Acid Effect on Tumor-Associated Myeloid-Derived Suppressor Cells

Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non-Small Cell Lung Cancer

An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2

NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication

Bid-Independent Mitochondrial Activation in Tumor Necrosis Factor Alpha-Induced Apoptosis and Liver Injury

Rapid Autopsy to Define Dendritic Cell Spatial Distribution and T Cell Association in Lung Adenocarcinoma

Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance

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