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Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects

British journal of clinical pharmacology, 2016-07, Vol.82 (1), p.139-148

2016

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Phase 1 and 2 Randomized Clinical Studies Determine Lack of Efficacy for Anti-IL-17C Antibody MOR106 in Moderate-Severe Atopic Dermatitis

Journal of clinical medicine, 2022-12, Vol.11 (23), p.7244

2022

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GLPG1205, a GPR84 Modulator: Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Subjects

Clinical pharmacology in drug development, 2021-09, Vol.10 (9), p.994-1006

2021

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Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial

Annals of the rheumatic diseases, 2013-05, Vol.72 (5), p.741-744

2013

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Mo1234 The FFA2 Antagonist GLPG0974: A Promising Approach to Treat Neutrophil-Driven Inflammation

Gastroenterology (New York, N.Y. 1943), 2014-05, Vol.146 (5), p.S-593-S-593

2014

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Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds

Bioorganic & medicinal chemistry, 2007-11, Vol.15 (22), p.6943-6955

2007

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Pharmacokinetics, Safety, and Tolerability of GLPG0259, a Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Inhibitor, Given as Single and Multiple Doses to Healthy Male Subjects

Drugs in R&D, 2012-09, Vol.12 (3), p.141-163

2012

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Norpiperidine Imidazoazepines as a New Class of Potent, Selective, and Nonsedative H 1 Antihistamines

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.2154-2166

2005

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Norpiperidine Imidazoazepines as a New Class of Potent, Selective, and Nonsedative H1 Antihistamines

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.2154-2166

2005

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Acetylcholine stimulates the release of prostacyclin by rabbit aorta endothelium

Journal of pharmacy and pharmacology, 1983-04, Vol.35 (4), p.251-252

1983

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Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid

Biochemical pharmacology, 1986-04, Vol.35 (8), p.1397-1400

1986

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Blood levels of 6-oxo-prostaglandin F1α during endotoxin-induced hypotension in rabbits

European journal of pharmacology, 1980-04, Vol.63 (1), p.47-56

1980

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Vitamin C increases the formation of prostacyclin by aortic rings from various species and neutralizes the inhibitory effect of 15‐hydroperoxy‐arachidonic acid

British journal of pharmacology, 1983-10, Vol.80 (2), p.249-254

1983

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Antioxidants increase the formation of 6-oxo- PGF 1α by ram seminal vesicle microsomes

Biochemical pharmacology, 1981, Vol.30 (20), p.2811-2815

1981

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INFLUENCE OF VITAMIN C ON THE PROSTACYCLIN BIOSYNTHESIS. (DUTCH TEXT) (ARACHIDOUIC ACID, ATHEROSCLEROSIS)

BEETENS, JOHAN R

1983

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Antioxidants increase the formation of 6-oxo-PGF1 alpha by ram seminal vesicle microsomes

Biochemical pharmacology, 1981-10, Vol.30 (20), p.2811-2815

1981

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Blood levels of 6-oxo-prostaglandin F 1α during endotoxin-induced hypotension in rabbits

European journal of pharmacology, 1980-04, Vol.63 (1), p.47-56

1980

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Gas chromatographic—mass spectrometric determination of 11-dehydrothromboxane B 2 in human urine

Journal of chromatography. Biomedical applications, 1992, Vol.577 (1), p.1-7

1992

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Gas chromatographic-mass spectrometric determination of 11-dehydrothromboxane B2 in human urine

Journal of chromatography, 1992-05, Vol.577 (1), p.1-7

1992

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Determination of 6-keto-PGF 1α, 2,3-dinor-6-keto-PGF 1α, thromboxane B 2, 2,3-dinor-thromboxane B 2, PGE 2, PGD 2 and PGF 2α in human urine by gas chromatography—negative ion chemical ionization mass spectrometry

Journal of chromatography. Biomedical applications, 1991, Vol.562 (1), p.599-611

1991

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Determination of 6-keto-PGF1α, 2-3-dinor-6-keto-PGF1α, thromboxane B2, 2,3-dinor-thromboxane B2, PGE2, PGD2 and PGF2α in human urine by gas chromatography-negative ion chemical ionization mass spectrometry

Journal of chromatography, 1991-01, Vol.562 (1-2), p.599-611

1991

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Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects

Phase 1 and 2 Randomized Clinical Studies Determine Lack of Efficacy for Anti-IL-17C Antibody MOR106 in Moderate-Severe Atopic Dermatitis

GLPG1205, a GPR84 Modulator: Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Subjects

Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial

Mo1234 The FFA2 Antagonist GLPG0974: A Promising Approach to Treat Neutrophil-Driven Inflammation

Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds

Pharmacokinetics, Safety, and Tolerability of GLPG0259, a Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Inhibitor, Given as Single and Multiple Doses to Healthy Male Subjects

Norpiperidine Imidazoazepines as a New Class of Potent, Selective, and Nonsedative H 1 Antihistamines

Norpiperidine Imidazoazepines as a New Class of Potent, Selective, and Nonsedative H1 Antihistamines

Acetylcholine stimulates the release of prostacyclin by rabbit aorta endothelium

Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid

Blood levels of 6-oxo-prostaglandin F1α during endotoxin-induced hypotension in rabbits

Vitamin C increases the formation of prostacyclin by aortic rings from various species and neutralizes the inhibitory effect of 15‐hydroperoxy‐arachidonic acid

Antioxidants increase the formation of 6-oxo- PGF 1α by ram seminal vesicle microsomes

INFLUENCE OF VITAMIN C ON THE PROSTACYCLIN BIOSYNTHESIS. (DUTCH TEXT) (ARACHIDOUIC ACID, ATHEROSCLEROSIS)

Antioxidants increase the formation of 6-oxo-PGF1 alpha by ram seminal vesicle microsomes

Blood levels of 6-oxo-prostaglandin F 1α during endotoxin-induced hypotension in rabbits

Gas chromatographic—mass spectrometric determination of 11-dehydrothromboxane B 2 in human urine

Gas chromatographic-mass spectrometric determination of 11-dehydrothromboxane B2 in human urine

Determination of 6-keto-PGF 1α, 2,3-dinor-6-keto-PGF 1α, thromboxane B 2, 2,3-dinor-thromboxane B 2, PGE 2, PGD 2 and PGF 2α in human urine by gas chromatography—negative ion chemical ionization mass spectrometry

Determination of 6-keto-PGF1α, 2-3-dinor-6-keto-PGF1α, thromboxane B2, 2,3-dinor-thromboxane B2, PGE2, PGD2 and PGF2α in human urine by gas chromatography-negative ion chemical ionization mass spectrometry

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