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Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17644-17648

2011

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Structure of the Human MutSα DNA Lesion Recognition Complex

Molecular cell, 2007-05, Vol.26 (4), p.579-592

2007

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Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (23), p.6010-6015

2017

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Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Cell, 2011-04, Vol.145 (2), p.212-223

2011

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Structures of Mismatch Replication Errors Observed in a DNA Polymerase

Cell, 2004-03, Vol.116 (6), p.803-816

2004

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Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5324

2024

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Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Cell reports (Cambridge), 2017-10, Vol.21 (5), p.1375-1385

2017

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Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

Nature, 2004-09, Vol.431 (7005), p.217-221

2004

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Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

Communications chemistry, 2023-08, Vol.6 (1), p.168-12, Article 168

2023

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The Closing Mechanism of DNA Polymerase I at Atomic Resolution

Structure (London), 2015-09, Vol.23 (9), p.1609-1620

2015

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Processive DNA Synthesis Observed in a Polymerase Crystal Suggests a Mechanism for the Prevention of Frameshift Mutations

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (7), p.3895-3900

2003

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The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis

Structure (London), 2010-01, Vol.18 (1), p.83-93

2010

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Reaction path of protein farnesyltransferase at atomic resolution

Nature (London), 2002-10, Vol.419 (6907), p.645-650

2002

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Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics

Nucleic acids research, 2023-06, Vol.51 (11), p.5883-5894

2023

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Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33217-33223

2009

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Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate

The Journal of biological chemistry, 2008-11, Vol.283 (46), p.31933-31940

2008

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Accurate Identification of Periplasmic Urea-binding Proteins by Structure- and Genome Context-assisted Functional Analysis

Journal of molecular biology, 2024-09, Vol.436 (22), p.168780, Article 168780

2024

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Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution

Science (American Association for the Advancement of Science), 1997-03, Vol.275 (5307), p.1800-1804

1997

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The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

The Journal of biological chemistry, 2011-06, Vol.286 (22), p.19758-19767

2011

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Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication

Journal of molecular biology, 2005-02, Vol.280 (5), p.3764-3770

2005

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Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.13753-13770

2022

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The basis for K-Ras4B binding specificity to protein farnesyl-transferase revealed by 2 Å resolution ternary complex structures

Structure (London), 2000-02, Vol.8 (2), p.209-222

2000

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Conversion of Protein Farnesyltransferase to a Geranylgeranyltransferase

Biochemistry (Easton), 2006-08, Vol.45 (32), p.9746-9755

2006

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Observing Translesion Synthesis of an Aromatic Amine DNA Adduct by a High-fidelity DNA Polymerase

The Journal of biological chemistry, 2004-11, Vol.279 (48), p.50280-50285

2004

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Structure‐based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose‐binding protein

Protein science, 2007-10, Vol.16 (10), p.2240-2250

2007

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Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Structure of the Human MutSα DNA Lesion Recognition Complex

Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Structures of Mismatch Replication Errors Observed in a DNA Polymerase

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

The Closing Mechanism of DNA Polymerase I at Atomic Resolution

Processive DNA Synthesis Observed in a Polymerase Crystal Suggests a Mechanism for the Prevention of Frameshift Mutations

The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis

Reaction path of protein farnesyltransferase at atomic resolution

Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics

Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate

Accurate Identification of Periplasmic Urea-binding Proteins by Structure- and Genome Context-assisted Functional Analysis

Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution

The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication

Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

The basis for K-Ras4B binding specificity to protein farnesyl-transferase revealed by 2 Å resolution ternary complex structures

Conversion of Protein Farnesyltransferase to a Geranylgeranyltransferase

Observing Translesion Synthesis of an Aromatic Amine DNA Adduct by a High-fidelity DNA Polymerase

Structure‐based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose‐binding protein

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