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6-LB: GPR119 Agonist PRM A Increases Glucagon Response to Hypoglycemia in Rats

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1467-1470

2005

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Discovery of 1-[3-(4-Bromo-2-methyl-2 H -pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine 2A Inverse Agonists for the Treatment of Insomnia

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.1923-1936

2010

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Can peptides be mimicked?

Drug Discovery Today, 2000-08, Vol.5 (8), p.354-363

Beeley, Nigel R.A

2000

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Discovery of 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine2A Inverse Agonists for the Treatment of Insomnia

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.1923-1936

2010

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Improved tumor targeting with chemically cross-linked recombinant antibody fragments

Cancer research (Chicago, Ill.), 1994-12, Vol.54 (23), p.6176-6185

1994

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Discovery and SAR of new benzazepines as potent and selective 5-HT 2C receptor agonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1467-1470

2005

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An in Vivo Model for Screening Peptidomimetic Inhibitors of Gelatinase A

Journal of pharmaceutical sciences, 1995-04, Vol.84 (4), p.404-409

1995

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Section Review Oncologic, Endocrine & Metabolic: The amylin, CGRP and calcitonin family of peptides

Expert opinion on therapeutic patents, 1996-06, Vol.6 (6), p.555-567

1996

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Medicinal Chemistry – An Introduction

Drug discovery today, 2001-04, Vol.6 (7), p.346-346

Beeley, Nigel R.A

2001

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A revolution in drug discovery

BMJ. British medical journal (International ed.), 2000-09, Vol.321 (7261), p.581

International edition, 2000

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Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (10), p.2565-2569

2005

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Corrigendum

Drug discovery today, 2000-10, Vol.5 (10), p.454

Beeley, Nigel R.A.

2000

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Peptidomimetics and small-molecule drug design: Towards improved bioavailability and in vivo stability

Trends in biotechnology, 1994-06, Vol.12 (6), p.213-216

Beeley, Nigel

1994

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GPCRs: an update on structural approaches to drug discovery

Targets, 2003-02, Vol.2 (1), p.19-25

2003

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Overview: Macrocyclic Chelators as Anticancer Agents in Radioimmunotherapy

Current Opinion on Therapeutic Patents, 1992-10, Vol.2 (10), p.1539-1553

1992

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A revolution in drug discovery. Combinatorial chemistry still needs logic to drive science forward

BMJ (Online), 2000-09, Vol.321 (7261), p.581

2000

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Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1467-1470

2005

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Synthesis of a kinetically stable yttrium-90 labelled macrocycle―antibody conjugate

Journal of the Chemical Society. Chemical communications, 1989 (12), p.797-798

1989

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Cephalosporin Nitrogen Mustard Carbamate prodrugs for “ADEPT”

Tetrahedron letters, 1991-07, Vol.32 (27), p.3269-3272

1991

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Potent and selective inhibitors of gelatinase-a 1. hydroxamic acid derivatives

Bioorganic & medicinal chemistry letters, 1994, Vol.4 (23), p.2741-2746

1994

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Towards tumour imaging with indium-111 labelled macrocycle–antibody conjugates

Journal of the Chemical Society. Chemical communications, 1989 (12), p.794-796

1989

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6-LB: GPR119 Agonist PRM A Increases Glucagon Response to Hypoglycemia in Rats

Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2C Receptor Agonist for the Treatment of Obesity

Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity

Discovery of 1-[3-(4-Bromo-2-methyl-2 H -pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine 2A Inverse Agonists for the Treatment of Insomnia

Can peptides be mimicked?

Discovery of 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine2A Inverse Agonists for the Treatment of Insomnia

Improved tumor targeting with chemically cross-linked recombinant antibody fragments

Discovery and SAR of new benzazepines as potent and selective 5-HT 2C receptor agonists for the treatment of obesity

An in Vivo Model for Screening Peptidomimetic Inhibitors of Gelatinase A

Section Review Oncologic, Endocrine & Metabolic: The amylin, CGRP and calcitonin family of peptides

Medicinal Chemistry – An Introduction

A revolution in drug discovery

Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1

Corrigendum

Peptidomimetics and small-molecule drug design: Towards improved bioavailability and in vivo stability

GPCRs: an update on structural approaches to drug discovery

Overview: Macrocyclic Chelators as Anticancer Agents in Radioimmunotherapy

Discovery and Structure−Activity Relationship of (1 R )-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1 H -3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT 2C Receptor Agonist for the Treatment of Obesity

Discovery and Structure-Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-l-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2C Receptor Agonist for the Treatment of Obesity

A revolution in drug discovery. Combinatorial chemistry still needs logic to drive science forward

Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity

Synthesis of a kinetically stable yttrium-90 labelled macrocycle―antibody conjugate

Cephalosporin Nitrogen Mustard Carbamate prodrugs for “ADEPT”

Potent and selective inhibitors of gelatinase-a 1. hydroxamic acid derivatives

Towards tumour imaging with indium-111 labelled macrocycle–antibody conjugates

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