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Mechanical force application to the nucleus regulates nucleocytoplasmic transport

Nature cell biology, 2022-06, Vol.24 (6), p.896-905

2022

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The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

Nature communications, 2021-07, Vol.12 (1), p.4229-4229, Article 4229

2021

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In search of a softer environment

Nature materials, 2022-09, Vol.21 (9), p.995-996

2022

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Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding

Nature communications, 2016-08, Vol.7 (1), p.12490-12490, Article 12490

2016

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The laminin-keratin link shields the nucleus from mechanical deformation and signalling

Nature materials, 2023-11, Vol.22 (11), p.1409-1420

2023

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Forcing the reversibility of a mechanochemical reaction

Nature communications, 2018-08, Vol.9 (1), p.3155-9, Article 3155

2018

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Molecular Fluctuations as a Ruler of Force-Induced Protein Conformations

Nano letters, 2021-04, Vol.21 (7), p.2953-2961

2021

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The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins

Nature communications, 2015-08, Vol.6 (1), p.7894-7894, Article 7894

2015

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Tailoring protein nanomechanics with chemical reactivity

Nature communications, 2017-06, Vol.8 (1), p.15658-15658, Article 15658

2017

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Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

Cell, 2017-11, Vol.171 (6), p.1397-1410.e14

2017

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The Nanomechanics of Lipid Multibilayer Stacks Exhibits Complex Dynamics

Small (Weinheim an der Bergstrasse, Germany), 2017-06, Vol.13 (24), p.1700147-n/a

2017

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Mechanobiology—chemical origin of membrane mechanical resistance and force-dependent signaling

Current opinion in chemical biology, 2015-12, Vol.29, p.87-93

2015

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Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (24), p.4477-4480

2003

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Preventing Unplanned Perioperative Hypothermia in Children

AORN journal, 2017-02, Vol.105 (2), p.170-183

2017

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Steering chemical reactions with force

Nature reviews. Chemistry, 2017-11, Vol.1 (11), Article 0083

2017

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The role of single-protein elasticity in mechanobiology

Nature reviews. Materials, 2023-01, Vol.8 (1), p.10-24

2023

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The mechanical stability of proteins regulates their translocation rate into the cell nucleus

Nature physics, 2019-09, Vol.15 (9), p.973-981

2019

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Single-molecule Force Spectroscopy Predicts a Misfolded, Domain-swapped Conformation in human γD-Crystallin Protein

The Journal of biological chemistry, 2016-02, Vol.291 (8), p.4226-4235

2016

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Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection

Structure (London), 2017-01, Vol.25 (1), p.107-120

2017

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The reversibility of cellular mechano-activation

Current opinion in cell biology, 2023-10, Vol.84, p.102229-102229, Article 102229

2023

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Dihydropyridazinone cardiotonics. The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.1832-1840

1986

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Structure-activity relationships of arylimidazopyridine cardiotonics: discovery and inotropic activity of 2-[2-methoxy-4-(methylsulfinyl)phenyl]-1H-imidazo[4,5-c]pyridine

Journal of medicinal chemistry, 1985-06, Vol.28 (6), p.717-727

1985

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Structure-activity relationships of (arylalkyl)imidazole anticonvulsants: comparison of the (fluorenylalkyl)imidazoles with nafimidone and denzimol

Journal of medicinal chemistry, 1986-09, Vol.29 (9), p.1577-1586

1986

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Preaching Wesley's Ordo Salutis: A Study in Wesleyan Theology Today

Beedle, Edward E

2017

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Bipyridine cardiotonics: the three-dimensional structures of amrinone and milrinone

Journal of medicinal chemistry, 1986-05, Vol.29 (5), p.635-640

1986

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Mechanical force application to the nucleus regulates nucleocytoplasmic transport

The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

In search of a softer environment

Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding

The laminin-keratin link shields the nucleus from mechanical deformation and signalling

Forcing the reversibility of a mechanochemical reaction

Molecular Fluctuations as a Ruler of Force-Induced Protein Conformations

The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins

Tailoring protein nanomechanics with chemical reactivity

Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

The Nanomechanics of Lipid Multibilayer Stacks Exhibits Complex Dynamics

Mechanobiology—chemical origin of membrane mechanical resistance and force-dependent signaling

Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake

Preventing Unplanned Perioperative Hypothermia in Children

Steering chemical reactions with force

The role of single-protein elasticity in mechanobiology

The mechanical stability of proteins regulates their translocation rate into the cell nucleus

Single-molecule Force Spectroscopy Predicts a Misfolded, Domain-swapped Conformation in human γD-Crystallin Protein

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection

The reversibility of cellular mechano-activation

Dihydropyridazinone cardiotonics. The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one

Structure-activity relationships of arylimidazopyridine cardiotonics: discovery and inotropic activity of 2-[2-methoxy-4-(methylsulfinyl)phenyl]-1H-imidazo[4,5-c]pyridine

Structure-activity relationships of (arylalkyl)imidazole anticonvulsants: comparison of the (fluorenylalkyl)imidazoles with nafimidone and denzimol

Preaching Wesley's Ordo Salutis: A Study in Wesleyan Theology Today

Bipyridine cardiotonics: the three-dimensional structures of amrinone and milrinone

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