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Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains

Developmental cell, 2020-11, Vol.55 (4), p.468-482.e7

2020

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The LIM domain: from the cytoskeleton to the nucleus

Nature reviews. Molecular cell biology, 2004-11, Vol.5 (11), p.920-931

2004

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LIM domains target actin regulators paxillin and zyxin to sites of stress fiber strain

PloS one, 2013-08, Vol.8 (8), p.e69378-e69378

2013

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Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

Molecular biology of the cell, 2012-05, Vol.23 (10), p.1846-1859

2012

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A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair

Developmental cell, 2010-09, Vol.19 (3), p.365-376

2010

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Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

The Journal of cell biology, 2005-10, Vol.171 (2), p.209-215

2005

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From the membrane to the nucleus and back again: bifunctional focal adhesion proteins

Current opinion in cell biology, 2006-10, Vol.18 (5), p.524-532

2006

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The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics

PloS one, 2017-03, Vol.12 (3), p.e0171728-e0171728

2017

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Lateral Communication between Stress Fiber Sarcomeres Facilitates a Local Remodeling Response

Biophysical journal, 2012-11, Vol.103 (10), p.2082-2092

2012

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mechanical-biochemical feedback loop regulates remodeling in the actin cytoskeleton

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.17528-17533

2014

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A Novel Role for Keratin 17 in Coordinating Oncogenic Transformation and Cellular Adhesion in Ewing Sarcoma

Molecular and Cellular Biology, 2013-11, Vol.33 (22), p.4448-4460

2013

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STRIATED MUSCLE CYTOARCHITECTURE: An Intricate Web of Form and Function

Annual review of cell and developmental biology, 2002-01, Vol.18 (1), p.637-706

2002

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Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling

The Journal of cell biology, 2006-02, Vol.172 (5), p.771-782

2006

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Nuclear pore complexes concentrate on Actin/LINC/Lamin nuclear lines in response to mechanical stress in a SUN1 dependent manner

Heliyon, 2022-12, Vol.8 (12), p.e12147-e12147, Article e12147

2022

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Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility

Molecular biology of the cell, 2022-09, Vol.33 (11), p.1-ar100

2022

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EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma

Genes & cancer, 2015-03, Vol.6 (3-4), p.129-143

2015

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Elevated expression of the integrin-associated protein PINCH suppresses the defects of Drosophila melanogaster muscle hypercontraction mutants

PLoS genetics, 2013-03, Vol.9 (3), p.e1003406-e1003406

2013

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Mechanical stress triggers nuclear remodeling and the formation of Transmembrane Actin Nuclear lines with associated Nuclear Pore Complexes

Molecular biology of the cell, 2020-07, Vol.31 (16), p.mbcE19010027-1787

2020

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TRIP6, a novel molecular partner of the MAGI‐1 scaffolding molecule, promotes invasiveness

The FASEB journal, 2009-03, Vol.23 (3), p.916-928

2009

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Cysteine-Rich LIM-Only Proteins CRP1 and CRP2 Are Potent Smooth Muscle Differentiation Cofactors

Developmental cell, 2003, Vol.4 (1), p.107-118

2003

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Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth

Clinical cancer research, 2014-09, Vol.20 (17), p.4584-4597

2014

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Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes

Development (Cambridge), 2003-06, Vol.130 (12), p.2611-2621

2003

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Characterization of RACK1 function in Drosophila development

Developmental dynamics, 2007-08, Vol.236 (8), p.2207-2215

2007

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Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha

Scientific reports, 2020-11, Vol.10 (1), p.19303-19303, Article 19303

2020

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Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility

Molecular systems biology, 2016-03, Vol.12 (3), p.860-n/a

2016

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Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains

The LIM domain: from the cytoskeleton to the nucleus

LIM domains target actin regulators paxillin and zyxin to sites of stress fiber strain

Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair

Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

From the membrane to the nucleus and back again: bifunctional focal adhesion proteins

The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics

Lateral Communication between Stress Fiber Sarcomeres Facilitates a Local Remodeling Response

mechanical-biochemical feedback loop regulates remodeling in the actin cytoskeleton

A Novel Role for Keratin 17 in Coordinating Oncogenic Transformation and Cellular Adhesion in Ewing Sarcoma

STRIATED MUSCLE CYTOARCHITECTURE: An Intricate Web of Form and Function

Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling

Nuclear pore complexes concentrate on Actin/LINC/Lamin nuclear lines in response to mechanical stress in a SUN1 dependent manner

Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility

EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma

Elevated expression of the integrin-associated protein PINCH suppresses the defects of Drosophila melanogaster muscle hypercontraction mutants

Mechanical stress triggers nuclear remodeling and the formation of Transmembrane Actin Nuclear lines with associated Nuclear Pore Complexes

TRIP6, a novel molecular partner of the MAGI‐1 scaffolding molecule, promotes invasiveness

Cysteine-Rich LIM-Only Proteins CRP1 and CRP2 Are Potent Smooth Muscle Differentiation Cofactors

Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth

Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes

Characterization of RACK1 function in Drosophila development

Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha

Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility

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