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Impact of Complex Apoptotic Signaling Pathways on Cancer Cell Sensitivity to Therapy

Cancers, 2024-02, Vol.16 (5), p.984

2024

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Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells

The Journal of pharmacology and experimental therapeutics, 2008-01, Vol.324 (1), p.95-102

2008

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Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20778-20783

2011

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MicroRNA-mediated Regulation of Ubc9 Expression in Cancer Cells

Clinical cancer research, 2009-03, Vol.15 (5), p.1550-1557

2009

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Preparing for the End Game

Journal of clinical oncology, 2023-01, Vol.41 (3), p.701-702

Beck, William T

2023

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Identification of a novel estrogen response element in the Breast Cancer Resistance Protein (ABCG2) gene

Cancer research (Chicago, Ill.), 2004-02, Vol.64 (4), p.1247-1251

2004

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Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells

The Journal of pharmacology and experimental therapeutics, 2009-08, Vol.330 (2), p.423-429

2009

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Alternative Splicing of the Multidrug Resistance Protein 1/ATP Binding Cassette Transporter Subfamily Gene in Ovarian Cancer Creates Functional Splice Variants and Is Associated with Increased Expression of the Splicing Factors PTB and SRp20

Clinical cancer research, 2004-07, Vol.10 (14), p.4652-4660

2004

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Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine

Biochimica et biophysica acta, 2011-07, Vol.1809 (7), p.295-305

2011

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Identification of Estrogen-responsive Genes Using a Genome-wide Analysis of Promoter Elements for Transcription Factor Binding Sites

The Journal of biological chemistry, 2005-06, Vol.280 (22), p.21491-21497

2005

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Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference

Molecular cancer therapeutics, 2004-12, Vol.3 (12), p.1577-1584

2004

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Gam1-associated alterations of drug responsiveness through activation of apoptosis

Molecular cancer therapeutics, 2007-06, Vol.6 (6), p.1823-1830

2007

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Nucleolar Delocalization of Human Topoisomerase I in Response to Topotecan Correlates with Sumoylation of the Protein

The Journal of biological chemistry, 2002-01, Vol.277 (4), p.2958-2964

2002

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Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and Its Analogues

Journal of medicinal chemistry, 2011-08, Vol.54 (16), p.5937-5948

2011

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Sumoylation of Topoisomerase I Is Involved in Its Partitioning between Nucleoli and Nucleoplasm and Its Clearing from Nucleoli in Response to Camptothecin

The Journal of biological chemistry, 2002-10, Vol.277 (42), p.40020-40026

2002

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Novel regulation of nuclear factor-YB by miR-485-3p affects the expression of DNA topoisomerase IIα and drug responsiveness

Molecular pharmacology, 2011-04, Vol.79 (4), p.735-741

2011

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A role for Ubc9 in tumorigenesis

Oncogene, 2005-04, Vol.24 (16), p.2677-2683

2005

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A high-throughput assay to identify small-molecule modulators of alternative pre-mRNA splicing

Journal of biomolecular screening, 2013-02, Vol.18 (2), p.180-190

2013

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Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines

International journal of biochemistry and molecular biology, 2016, Vol.7 (2), p.27-47

2016

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Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

BMC medical genomics, 2014-05, Vol.7 Suppl 1 (S1), p.S1-S1, Article S1

2014

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Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1

Biochimica et biophysica acta, 2013-12, Vol.1829 (12), p.1288-1299

2013

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Rapid Exchange of Mammalian Topoisomerase IIα at Kinetochores and Chromosome Arms in Mitosis

The Journal of cell biology, 2002-07, Vol.158 (1), p.23-29

2002

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Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53

Cancer research (Chicago, Ill.), 1998-12, Vol.58 (24), p.5762-5769

1998

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Tumor cell resistance to DNA topoisomerase II inhibitors: new developments

Drug resistance updates, 1999-12, Vol.2 (6), p.382-389

1999

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Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs

Cancer research (Chicago, Ill.), 2004-04, Vol.64 (8), p.2793-2798

2004

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Impact of Complex Apoptotic Signaling Pathways on Cancer Cell Sensitivity to Therapy

Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells

Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells

MicroRNA-mediated Regulation of Ubc9 Expression in Cancer Cells

Preparing for the End Game

Identification of a novel estrogen response element in the Breast Cancer Resistance Protein (ABCG2) gene

Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells

Alternative Splicing of the Multidrug Resistance Protein 1/ATP Binding Cassette Transporter Subfamily Gene in Ovarian Cancer Creates Functional Splice Variants and Is Associated with Increased Expression of the Splicing Factors PTB and SRp20

Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine

Identification of Estrogen-responsive Genes Using a Genome-wide Analysis of Promoter Elements for Transcription Factor Binding Sites

Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference

Gam1-associated alterations of drug responsiveness through activation of apoptosis

Nucleolar Delocalization of Human Topoisomerase I in Response to Topotecan Correlates with Sumoylation of the Protein

Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and Its Analogues

Sumoylation of Topoisomerase I Is Involved in Its Partitioning between Nucleoli and Nucleoplasm and Its Clearing from Nucleoli in Response to Camptothecin

Novel regulation of nuclear factor-YB by miR-485-3p affects the expression of DNA topoisomerase IIα and drug responsiveness

A role for Ubc9 in tumorigenesis

A high-throughput assay to identify small-molecule modulators of alternative pre-mRNA splicing

Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines

Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1

Rapid Exchange of Mammalian Topoisomerase IIα at Kinetochores and Chromosome Arms in Mitosis

Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53

Tumor cell resistance to DNA topoisomerase II inhibitors: new developments

Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs

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